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Nipocalimab, an anti-FcRn monoclonal antibody, in participants with moderate to severe active rheumatoid arthritis and inadequate response or intolerance to anti-TNF therapy: results from the phase 2a IRIS-RA study

Autor: Kaiyin Fei, Peter C Taylor, Tom WJ Huizinga, Georg Schett, Matthew J Loza, Chetan S Karyekar, Bei Zhou, Jocelyn H Leu, Qingmin Wang, Keying Ma, Fowzia Ibrahim, Yuan Xiong, Sheng Gao, Sophia G Liva, Jafar Sadik B Shaik, Rohit A Panchakshari, Harman Dhatt, Ricardo Rojo Cella, Carolyn A Cuff

Publikováno v: RMD Open, Vol 10, Iss 2 (2024)

Objectives To investigate the efficacy, safety, pharmacokinetics and pharmacodynamics of nipocalimab in participants with moderate to severe active rheumatoid arthritis (RA) and inadequate response or intolerance to ≥1 antitumour necrosis factor ag

Externí odkaz: https://doaj.org/article/e8783e06cebd4815857f9ccfd2c182ba

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Akademický článek

Alienation in Contemporary Sculpture between the Works of Anthony Caro and Tony Cragg (A Comparative Study)

Autor: Jafar Sadik Ayyed Ali

Publikováno v: الاكاديمي, Iss 90 (2018)

The subject of this research is the study of the formal alienation of contemporary English sculpture, by comparing the most important sculptors of the new contemporary generation. This research problem is to look for the important factors in the form

Externí odkaz: https://doaj.org/article/e7984320bd214bada691e6fdcb028b8f

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Akademický článek

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Akademický článek

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Akademický článek

Rapid and simultaneous quantitation of prostanoids by UPLC–MS/MS in rat brain

Autor: Shaik, Jafar Sadik B., Miller, Tricia M., Graham, Steven H., Manole, Mioara D., Poloyac, Samuel M.

Publikováno v: In Journal of Chromatography B 15 January 2014 945-946:207-216

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Comparison between physiologically based pharmacokinetic and population pharmacokinetic modelling to select paediatric doses of gepotidacin in plague

Autor: Caroline R Perry, Dung Nguyen, Jafar Sadik Shaik, David Gardiner, Etienne Dumont, Courtney Tiffany, Rajendra P. Singh, Mohammad Hossain, Aline Barth, Guoying Tai

Publikováno v: British Journal of Clinical Pharmacology. 88:416-428

AIMS To develop physiologically based pharmacokinetic (PBPK) and population pharmacokinetic (PopPK) models to predict effective doses of gepotidacin in paediatrics for the treatment of pneumonic plague (Yersinia pestis). METHODS A gepotidacin PBPK mo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eccd104e7e14ea0c2a0863cd9748aa10
https://doi.org/10.1111/bcp.14996

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The effect of paper-based manual and stereoscopic-based mobile augmented reality systems on knowledge retention

Autor: Mohamed Jafar Sadik, Meng Chun Lam, Nur Fazidah Elias

Publikováno v: Virtual Reality. 25:217-232

Augmented reality technology is attracting increased attention, given the popularity of the smartphone. The utilisation of the smartphone with AR technology is also enabling mobile augmented reality (MAR) to become accessible. Stereoscopic vision off

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fb39204a688bc637ec695920aa475a2c
https://doi.org/10.1007/s10055-020-00451-9

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Akademický článek

A Phase 1 Study to Evaluate the Pharmacokinetics and Safety of Cabotegravir in Patients With Hepatic Impairment and Healthy Matched Controls.

Autor: Shaik, Jafar Sadik B.¹ (AUTHOR) jafar-sadik.b.shaik@gsk.com, Ford, Susan L.² (AUTHOR), Lou, Yu³ (AUTHOR), Zhang, Zhiping³ (AUTHOR), Bakshi, Kalpana K.¹ (AUTHOR), Tenorio, Allan R.⁴ (AUTHOR), Trezza, Christine⁴ (AUTHOR), Spreen, William R.⁴ (AUTHOR), Patel, Parul⁴ (AUTHOR)

Publikováno v: Clinical Pharmacology in Drug Development. Jul2019, Vol. 8 Issue 5, p664-673. 10p.

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Pharmacokinetics and antiviral activity of cabotegravir and rilpivirine in cerebrospinal fluid following long-acting injectable administration in HIV-infected adults

Autor: Susan Swindells, Jafar Sadik Shaik, Scott Letendre, Herta Crauwels, Kenneth Sutton, Christopher J Bettacchi, Jerome deVente, Debbie Hagins, Ronald D'Amico, Parul Patel, Anthony Mills, Franco Felizarta, Susan L. Ford, Yu Lou

Publikováno v: The Journal of antimicrobial chemotherapy, vol 75, iss 3
Journal of Antimicrobial Chemotherapy

Background Long-acting (LA) formulations of cabotegravir, an HIV integrase inhibitor, and rilpivirine, an NNRTI, are in development as monthly or 2 monthly intramuscular (IM) injections for maintenance of virological suppression. Objectives To evalua

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::607640a08c19a6855de50558c93adb7e
https://doi.org/10.1093/jac/dkz504

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