Zobrazeno 1 - 10
of 155
pro vyhledávání: '"Jaeseong, Oh"'
Autor:
Yoonjin Kim, Sungyeun Bae, Kyung-Sang Yu, SeungHwan Lee, Chankyu Lee, Jinil Kim, Howard Her, Jaeseong Oh
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-7 (2024)
Abstract A randomized, active-controlled, double-blind, first-in-human, phase 1 study was conducted in healthy Korean adults to evaluate the safety, tolerability, and immunogenicity of EuNmCV-5, a new pentavalent meningococcal vaccine targeting serog
Externí odkaz:
https://doaj.org/article/14240b9592c14bf8bf9a044a5edf77fa
Autor:
Jihoon G. Yoon, Dong Geon Jang, Sung-Gyu Cho, Chaeyoung Lee, Shin Hye Noh, Soo Kyung Seo, Jung Woo Yu, Hyeon Woo Chung, KyeoRe Han, Soon Sung Kwon, Dai Hoon Han, Jaeseong Oh, In-Jin Jang, Sang-Hoon Kim, Young-Koo Jee, Hyun Lee, Dong Won Park, Jang Won Sohn, Ho Joo Yoon, Chul Hoon Kim, Jae Myun Lee, Sang-Heon Kim, Min Goo Lee
Publikováno v:
Experimental and Molecular Medicine, Vol 56, Iss 3, Pp 570-582 (2024)
Abstract Anti-tuberculosis (AT) medications, including isoniazid (INH), can cause drug-induced liver injury (DILI), but the underlying mechanism remains unclear. In this study, we aimed to identify genetic factors that may increase the susceptibility
Externí odkaz:
https://doaj.org/article/119002dbb031472bbb9999dad2b2d002
Autor:
Seolah Lee, Hyun Chul Kim, Yoonhyuk Jang, Han Sang Lee, Seon‐Jae Ahn, Soon‐Tae Lee, Keun‐Hwa Jung, Kyung‐Il Park, Ki‐Young Jung, Jaeseong Oh, SeungHwan Lee, Kyung‐Sang Yu, In‐Jin Jang, Soyoung Lee, Kon Chu, Sang Kun Lee
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 11, Iss 2, Pp 424-435 (2024)
Abstract Objective Despite the suggested topiramate serum level of 5–20 mg/L, numerous institutions have observed substantial drug response at lower levels. We aim to investigate the correlation between topiramate serum levels, drug responsiveness,
Externí odkaz:
https://doaj.org/article/d89b2860b4d64fadb1f2e7063f686429
Autor:
Ki Young Huh, Woo Kyung Chung, Jiyeon Park, SeungHwan Lee, Min‐Gul Kim, Jaeseong Oh, Kyung‐Sang Yu
Publikováno v:
Clinical and Translational Science, Vol 16, Iss 11, Pp 2177-2188 (2023)
Abstract Decentralized clinical trials (DCTs) leverage digital technologies to reduce dependency on study sites and intermediaries. DCT should be balanced with accessibility and data reliability while meeting regulatory requirements. Here, we conduct
Externí odkaz:
https://doaj.org/article/bb12b2c524c84c39bbedd1774c272e90
Autor:
Yoonjin Kim, Sungyeun Bae, Kyung-Sang Yu, SeungHwan Lee, Chankyu Lee, Jinil Kim, Howard Her, Jaeseong Oh
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/faf2eba13e974521a9b0b3248e346a58
Autor:
Heejae Won, Deok Yong Yoon, Sangmi Lee, Joo‐Youn Cho, Jaeseong Oh, In‐Jin Jang, Sang‐Ku Yoo, Kyung‐Sang Yu
Publikováno v:
Clinical and Translational Science, Vol 17, Iss 3, Pp n/a-n/a (2024)
Abstract Vutiglabridin, which affects the pharmacokinetics (PKs) of food, is currently under clinical development for the treatment of obesity. This study aimed to evaluate the effects of low‐ and high‐fat meals on PKs of vutiglabridin in healthy
Externí odkaz:
https://doaj.org/article/264b145fc6ce4606b5e8e24ef5de711e
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 12, Iss 9, Pp 1319-1334 (2023)
Abstract Tripegfilgrastim is a long‐acting granulocyte colony‐stimulating factor (G‐CSF) that has been used to prevent chemotherapy‐induced neutropenia in adults. This study aimed to establish a pharmacokinetic (PK)–pharmacodynamic (PD) mod
Externí odkaz:
https://doaj.org/article/68a8aaaf5b0a4c0ab208b20b6907eb07
Autor:
Min Young Park, Sungyeun Bae, Jung A Heo, Mihee Park, YuKyung Kim, Jumi Han, In‐Jin Jang, Kyung‐Sang Yu, Jaeseong Oh
Publikováno v:
Clinical and Translational Science, Vol 16, Iss 7, Pp 1163-1176 (2023)
Abstract Bersiporocin, a novel first‐in‐class prolyl‐tRNA synthetase (PRS) inhibitor currently under clinical development, was shown to exert an antifibrotic effect through the downregulation of collagen synthesis in various pulmonary fibrosis
Externí odkaz:
https://doaj.org/article/d80f7f55c88e4d17ade79b7552a0db14
Autor:
Bo Rim Kim, Leerang Lim, YoungRok Choi, Nam‐Joon Yi, Kwang‐Woong Lee, Kyung‐Suk Suh, Kyung‐Sang Yu, Jin Young Sohn, Raewon Jeong, Jaeseong Oh, Ho Geol Ryu
Publikováno v:
Clinical and Translational Science, Vol 16, Iss 7, Pp 1177-1185 (2023)
Abstract Antithrombin‐III (AT‐III) concentrates have been used in the immediate postoperative period after liver transplantation to prevent critical thrombosis. We aimed to investigate a more appropriate method for AT‐III concentrate administra
Externí odkaz:
https://doaj.org/article/54a83e171ae6436cbc579c06321388d1
Autor:
Woo Kyung Chung, Inyoung Hwang, Byungwook Kim, Jihyun Jung, Kyung‐Sang Yu, In‐Jin Jang, Jaeseong Oh
Publikováno v:
Clinical and Translational Science, Vol 16, Iss 3, Pp 512-523 (2023)
Abstract Valbenazine is a selective vesicular monoamine transporter 2 (VMAT2) inhibitor approved for tardive dyskinesia treatment by the US Food and Drug Administration; its major active metabolite (NBI‐98782) is a 45‐fold more potent inhibitor o
Externí odkaz:
https://doaj.org/article/35e6ca54ad554b33bc07d66db5a8067a