Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Jaeok Lee"'
Autor:
Hawon Yoo, Seul-Ki Choi, Jaeok Lee, So Hyeon Park, You Na Park, Soo-Yeon Hwang, Jae-Ho Shin, Younghwa Na, Youngjoo Kwon, Hwa Jeong Lee, Yun-Sil Lee
Publikováno v:
Pharmaceutics, Vol 13, Iss 5, p 630 (2021)
Relationships between heat shock protein 27 (HSP27) and cancer aggressiveness, metastasis, drug resistance, and poor patient outcomes in various cancer types including non-small cell lung cancer (NSCLC) were reported, and inhibition of HSP27 expressi
Externí odkaz:
https://doaj.org/article/3b6e8d0030624230831eee3ffb92d114
Publikováno v:
Pharmaceutics, Vol 13, Iss 4, p 572 (2021)
A high-performance liquid chromatography-ultraviolet detector (HPLC-UV) method has been used to quantify teicoplanin concentrations in human plasma. However, the limited analytical accuracy of previously bioanalytical methods for teicoplanin has give
Externí odkaz:
https://doaj.org/article/29a05529f3fb4486aacedf53db9e4233
Autor:
Jaeok Lee, Jiyeon Kang, Na-Yun Kwon, Aneesh Sivaraman, Ravi Naik, So-Young Jin, A. Reum Oh, Jae-Ho Shin, Younghwa Na, Kyeong Lee, Hwa-Jeong Lee
Publikováno v:
Pharmaceutics, Vol 13, Iss 4, p 559 (2021)
P-glycoprotein (P-gp) inhibition has been studied to overcome multidrug resistance in cancer chemotherapy but failed in clinical trials due to low/toxic effects. Recently, a dual modulation of transporters and natural derivatives have been examined t
Externí odkaz:
https://doaj.org/article/3038fe5315bd40aab778612323b0af6b
Autor:
Jaeok Lee, Song Wha Chae, LianJi Ma, So Yeon Lim, Sarah Alnajjar, Hea-Young Park Choo, Hwa Jeong Lee, Sandy Jeong Rhie
Publikováno v:
Pharmaceutics, Vol 11, Iss 11, p 593 (2019)
P-glycoprotein (P-gp) is known to be involved in multidrug resistance (MDR) and modulation of pharmacokinetic (PK) profiles of substrate drugs. Here, we studied the effects of synthesized ferulic acid (FA) derivatives on P-gp function in vitro and ex
Externí odkaz:
https://doaj.org/article/dff56457f17d4c0e907452c90b61b299
Publikováno v:
Pharmaceutics, Vol 11, Iss 9, p 482 (2019)
In a previous study, the specific NOX1/2/4 inhibitor Ewha-18278 was confirmed as a possible treatment for osteoporosis both in vitro and in vivo. Here, we investigated the pharmacokinetics (PK) of the compound by intravenous (IV) and oral administrat
Externí odkaz:
https://doaj.org/article/747046da6e5c44798e8ace5f6122abcf
Autor:
Jaeok Lee, Song Wha Chae, A Reum Oh, Ji Hye Yoo, Hea-Young Park Choo, Sandy Jeong Rhie, Hwa Jeong Lee
Publikováno v:
Pharmaceutics, Vol 11, Iss 1, p 23 (2019)
Paclitaxel (PTX) is an anticancer agent that is used to treat many cancers but it has a very low oral bioavailability due, at least in part, to the drug efflux transporter, P-glycoprotein (P-gp). Therefore, this study was performed to enhance oral bi
Externí odkaz:
https://doaj.org/article/deaeafddfe854e86a00acfe73355060a
Publikováno v:
Journal of Chemical Information and Modeling. 63:1429-1437
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c9cc33d7eb1acc29bdc6f11cd2ceafa
https://doi.org/10.1021/acs.jcim.2c01300
https://doi.org/10.1021/acs.jcim.2c01300
The source code for the BEAR method is available at https://github.com/cantabile57/BEAR.git including an example dataset. The following information is freely available from the corresponding author (wkim@ewha.ac.kr) upon request via email
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30b1676277087a3d958443c280dd5cc4
Publikováno v:
Journal of pharmaceutical investigation.
The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2, has resulted in acute respiratory distress, fatal systemic manifestations (extrapulmonary as well as pulmonary), and premature mortality amon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a2ec23889a3a97eef0476b5ef2d9dfc
https://pubmed.ncbi.nlm.nih.gov/36320434
https://pubmed.ncbi.nlm.nih.gov/36320434
Autor:
Youngjoo Kwon, You Na Park, Jaeok Lee, So Hyeon Park, Hawon Yoo, Soo Yeon Hwang, Yun Sil Lee, Younghwa Na, Hwa Jeong Lee, Seul Ki Choi, Jae Ho Shin
Publikováno v:
Pharmaceutics, Vol 13, Iss 630, p 630 (2021)
Pharmaceutics
Volume 13
Issue 5
Pharmaceutics
Volume 13
Issue 5
Relationships between heat shock protein 27 (HSP27) and cancer aggressiveness, metastasis, drug resistance, and poor patient outcomes in various cancer types including non-small cell lung cancer (NSCLC) were reported, and inhibition of HSP27 expressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4b83136e77d37af44acd81793600bdd
https://www.mdpi.com/1999-4923/13/5/630
https://www.mdpi.com/1999-4923/13/5/630