Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Jaemeun Lee"'
Publikováno v:
Molecular Brain, Vol 15, Iss 1, Pp 1-16 (2022)
Abstract Fibroblast growth factor 11 (FGF11) is a member of the intracellular fibroblast growth factor family. Here, we report the central role of FGF11 in the regulation of metabolism. Lentiviral injection of Fgf11 shRNA into the arcuate nucleus of
Externí odkaz:
https://doaj.org/article/f5ee1434bcbd4c1eaae81248f9f02a22
Autor:
Que Anh Vu, Hee Won Seo, Kwang-Eon Choi, Namju Kim, Yoo Na Kang, Jaemeun Lee, Sun-Hyun Park, Jee Taek Kim, Sohee Kim, Seong-Woo Kim
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
The retinal structural changes after subretinal implantation of three-dimensional (3D) microelectrodes were investigated in a mini pig. Three types of electrode were implanted into the subretinal spaces of nine mini pigs: 75-μm-high 3D electrodes on
Externí odkaz:
https://doaj.org/article/a9ef8c2d2ab6455dacf37e4bf45428a7
Autor:
Younshick Choi, Won-Seok Lee, Jaemeun Lee, Sun-Hyun Park, Sunwoung Kim, Ki-Hong Kim, Sua Park, Eun Ho Kim, Jong-Ki Kim
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 11, p 9552 (2023)
Iron accumulation in the brain accelerates Alzheimer’s disease progression. To cure iron toxicity, we assessed the therapeutic effects of noncontact transcranial electric field stimulation to the brain on toxic iron deposits in either the Aβ fibri
Externí odkaz:
https://doaj.org/article/7cdb1931b59840319e8e181b3bdda094
Publikováno v:
Organoid, Vol 1 (2021)
Background Toxicity evaluation based on two-dimensional cell culture shows differences from clinical results and has the disadvantage of not accurately reflecting cell-to-cell cross-signaling. Since almost all cells in the human body are arranged in
Externí odkaz:
https://doaj.org/article/6eb12bf6582946a09dd94459897e6210
Autor:
Jaemeun Lee, Kyungchan Kim, Jae Hyun Cho, Jin Young Bae, Timothy P. O’Leary, James D. Johnson, Yong Chul Bae, Eun-Kyoung Kim
Publikováno v:
JCI Insight, Vol 5, Iss 16 (2020)
Evidence has mounted that insulin can be synthesized in various brain regions, including the hypothalamus. However, the distribution and functions of insulin-expressing cells in the hypothalamus remain elusive. Herein, we show that in the mouse hypot
Externí odkaz:
https://doaj.org/article/b82ea44c618e407abe208646deac4692
Publikováno v:
PLoS ONE, Vol 10, Iss 1, p e0116972 (2015)
Autophagy is a lysosomal degradative pathway that plays an important role in maintaining cellular homeostasis. We previously showed that the inhibition of autophagy causes pancreatic β-cell apoptosis, suggesting that autophagy is a protective mechan
Externí odkaz:
https://doaj.org/article/6adbaaa135704193ace6d7e8c5aa4246
Autor:
Jingxian Wu, Jaemeun Lee, Joo Young Jung, Jeong Ho Hwang, Ki‐Suk Kim, Mikyung Shin, Haeshin Lee, Sun‐Hyun Park
Publikováno v:
Advanced Materials.
Autor:
Jieun Kim, Seungbok Lee, Jaemeun Lee, Jong-Chan Park, Kyung Hyun Kim, Jung Min Ko, Sun-Hyun Park, Seung-Ki Kim, Inhee Mook-Jung, Ji Yeoun Lee
Publikováno v:
Molecular genetics and metabolism. 136(2)
Phenylketonuria (PKU) is a common genetic metabolic disorder that causes phenylalanine accumulation in the blood. The most serious symptoms are related to the brain, as intellectual disability, seizure, and microcephaly are commonly found in poorly t
Autor:
Namju Kim, Yoo Na Kang, Hee Won Seo, Sun-Hyun Park, Jee Taek Kim, Soohee Kim, Kwang-Eon Choi, Jaemeun Lee, Que Anh Vu, Seong Woo Kim
Publikováno v:
SSRN Electronic Journal.
Publikováno v:
Organoid. 1:e7
Toxicity evaluation based on two-dimensional cell culture shows differences from clinical results and has the disadvantage of not accurately reflecting cell-to-cell cross-signaling. Since almost all cells in the human body are arranged in a three-dim