Structure and dynamics of the quaternary hunchback mRNA translation repression complex

Autor: Janosch Hennig, Pawel Masiewicz, Mikhail M. Savitski, Frank Gabel, Jochen S. Hub, Mandy Rettel, Bernd Simon, Brice Murciano, Jakub Macošek, Kathryn Perez, Miloš T. Ivanović, Inga Loedige, Sophie L. Winter, Pravin Kumar Ankush Jagtap, Jaelle Foot, Johanna-Barbara Linse, Karine Lapouge

Publikováno v: Nucleic Acids Research
Nucleic Acids Research, Oxford University Press, 2021, 49 (15), pp.8866-8885. ⟨10.1093/nar/gkab635⟩
Nucleic Acids Research, 2021, 49 (15), pp.8866-8885. ⟨10.1093/nar/gkab635⟩
Nucleic acids research 49(15), 8866-8885 (2021). doi:10.1093/nar/gkab635

A key regulatory process during Drosophila development is the localized suppression of the hunchback mRNA translation at the posterior, which gives rise to a hunchback gradient governing the formation of the anterior-posterior body axis. This suppres

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81be314ab74e25227140230362f0d50e
https://pubmed.ncbi.nlm.nih.gov/34329466

Structure and dynamics of the platelet integrin-binding C4 domain of von Willebrand factor

Autor: Emma-Ruoqi Xu, Jaelle Foot, Reinhard Schneppenheim, Frauke Gräter, Bernd Simon, Janosch Hennig, Po-chia Chen, Katra Kolšek, Tobias Obser, Camilo Aponte-Santamaría, Sören von Bülow, Peter J. Lenting, Matthias Wilmanns, Cécile V. Denis

Von Willebrand factor (VWF) is a key player in the regulation of hemostasis by promoting recruitment of platelets to sites of vascular injury. An array of 6 C domains forms the dimeric C-terminal VWF stem. Upon shear force activation, the stem adopts

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f8e0bfb6f800d81edd3def6b1de4a02
https://europepmc.org/articles/PMC6450055/