Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Jaejun Rhie"'
Autor:
Woori Shin, Hyun Tae Lee, Heejin Lim, Sang Hyung Lee, Ji Young Son, Jee Un Lee, Ki-Young Yoo, Seong Eon Ryu, Jaejun Rhie, Ju Yeon Lee, Yong-Seok Heo
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Blocking B-cell activating factor (BAFF), an important soluble factor for B-cell responses, with specific antibodies is approved for treating autoimmune disorders. Here the authors show, with structural data, that antibody-BAFF interactions not only
Externí odkaz:
https://doaj.org/article/e330576c14f6477d992a74d39ff8392f
Autor:
Sang Hyung Lee, Hyun Tae Lee, Woori Shin, Seong Eon Ryu, Jee Un Lee, Heejin Lim, Yong-Seok Heo, Jaejun Rhie, Ji Young Son, Ki Young Yoo, Ju Yeon Lee
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Nature Communications
Nature Communications
BAFF, a member of the TNF superfamily, has been recognized as a good target for autoimmune diseases. Belimumab, an anti-BAFF monoclonal antibody, was approved by the FDA for use in treating systemic lupus erythematosus. However, the molecular basis o