Výsledky vyhledávání - "Jaehun Cheong"

Akademický článek

Auranofin accelerates spermidine-induced apoptosis via reactive oxygen species generation and suppression of PI3K/Akt signaling pathway in hepatocellular carcinoma

Autor: Hyun Hwangbo, Da Hye Kim, Min Yeong Kim, Seon Yeong Ji, EunJin Bang, Su Hyun Hong, Yung Hyun Choi, JaeHun Cheong

Publikováno v: Fisheries and Aquatic Sciences, Vol 26, Iss 2, Pp 133-144 (2023)

Auranofin is a US Food and Drug Administration (FDA)-approved anti-arthritis medication that functions as a thioredoxin reductase inhibitor. Spermidine, a polyamine present in marine algae, can exert various physiological functions. Herein, we examin

Externí odkaz: https://doaj.org/article/50b8fa2743624016a5e29b5c22f6f52e

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Akademický článek

Distribution of hepatitis B virus genotypes in the general population of Myanmar via nationwide study

Autor: Yi Yi Kyaw, Aye Aye Lwin, Khin Saw Aye, Hlaing Myat Thu, Moh Moh Htun, Hnin Ohmar Soe, Kay Thi Aye, Kyaw Zin Thant, Hyeon Jeong Hwang, JaeHun Cheong

Publikováno v: BMC Infectious Diseases, Vol 20, Iss 1, Pp 1-11 (2020)

Abstract Background Hepatitis B virus (HBV) infections are a severe health concern worldwide. HBV is a DNA virus with a rapid rate of mutation. Based on heterogeneity of the nucleotide sequence, the HBV strains are divided into nine genotypes, each w

Externí odkaz: https://doaj.org/article/1aa30d3d819043559335da241a49cc56

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Akademický článek

Betulinic Acid Restricts Human Bladder Cancer Cell Proliferation In Vitro by Inducing Caspase-Dependent Cell Death and Cell Cycle Arrest, and Decreasing Metastatic Potential

Autor: So Young Kim, Hyun Hwangbo, Min Yeong Kim, Seon Yeong Ji, Da Hye Kim, Hyesook Lee, Gi-Young Kim, Sung-Kwon Moon, Sun-Hee Leem, Seok Joong Yun, Wun-Jae Kim, JaeHun Cheong, Cheol Park, Yung Hyun Choi

Publikováno v: Molecules, Vol 26, Iss 5, p 1381 (2021)

Betulinic acid (BA) is a naturally occurring pentacyclic triterpenoid and generally found in the bark of birch trees (Betula sp.). Although several studies have been reported that BA has diverse biological activities, including anti-tumor effects, th

Externí odkaz: https://doaj.org/article/ed38edcfa98b4eed9c68fcaa2989f993

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Akademický článek

Auranofin Attenuates Non-Alcoholic Fatty Liver Disease by Suppressing Lipid Accumulation and NLRP3 Inflammasome-Mediated Hepatic Inflammation In Vivo and In Vitro

Autor: Hyun Hwangbo, Min Yeong Kim, Seon Yeong Ji, So Young Kim, Hyesook Lee, Gi-Young Kim, Cheol Park, Young-Sam Keum, Su Hyun Hong, Jaehun Cheong, Yung Hyun Choi

Publikováno v: Antioxidants, Vol 9, Iss 11, p 1040 (2020)

Non-alcoholic fatty liver disease (NAFLD) causes liver dysfunction and is associated with obesity and type 2 diabetes. Chronic inflammation is associated not only with the development of NAFLD, but also with hepatic diseases, including steatohepatiti

Externí odkaz: https://doaj.org/article/ca28950603d54d4096b9ae6bd79d4a4a

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Akademický článek

Hepatitis B virus X protein impairs hepatic insulin signaling through degradation of IRS1 and induction of SOCS3.

Autor: KyeongJin Kim, Kook Hwan Kim, JaeHun Cheong

Publikováno v: PLoS ONE, Vol 5, Iss 3, p e8649 (2010)

Hepatitis B virus (HBV) is a major cause of chronic liver diseases, and frequently results in hepatitis, cirrhosis, and ultimately hepatocellular carcinoma. The role of HCV in associations with insulin signaling has been elucidated. However, the path

Externí odkaz: https://doaj.org/article/51286df15bee4ab486786c18f64c5ab7

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Particulate matter 2.5 promotes inflammation and cellular dysfunction via reactive oxygen species/p38 MAPK pathway in primary rat corneal epithelial cells

Autor: Da Hye Kim, Hyesook Lee, Hyun Hwangbo, So Young Kim, Seon Yeong Ji, Min Yeong Kim, Seh-Kwang Park, Sung-Ho Park, Mi-Young Kim, Gi-Young Kim, Jaehun Cheong, Soo-Wan Nam, Yung Hyun Choi

Publikováno v: Cutaneous and Ocular Toxicology. 41:273-284

Numerous studies have linked particulate matter2.5 (PM2.5) to ocular surface diseases, but few studies have been conducted on the biological effect of PM2.5 on the cornea. The objective of this study was to evaluate the harmful effect of PM2.5 on pri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6680efa15781d0f4e48c0a6ab273fd0
https://doi.org/10.1080/15569527.2022.2122489

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The Analyses of Cetacean Virus-Responsive Genes Reveal Evolutionary Marks in Mucosal Immunity-Associated Genes

Autor: Oksung Chung, Ye-Eun Jung, Kyeong Won Lee, Young Jun An, Jungeun Kim, Yoo-Rim Roh, Jong Bhak, Kiejung Park, Jessica A. Weber, Jaehun Cheong, Sun-Shin Cha, Jung-Hyun Lee, Hyung-Soon Yim

Publikováno v: Biochemical Genetics. 60:2299-2312

Viruses are the most common and abundant organisms in the marine environment. To better understand how cetaceans have adapted to this virus-rich environment, we compared cetacean virus-responsive genes to those from terrestrial mammals. We identified

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d48c8600526478651a525d1baaad5d4c
https://doi.org/10.1007/s10528-022-10221-8

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