Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Jaechul Shim"'
Autor:
Jaechul Shim, Kyung-Jin Lee
Publikováno v:
Physical Review B. 106
Publikováno v:
Physical review letters. 125(2)
We theoretically show that the coupling between magnons in an antiferromagnetically coupled ferrimagnet and microwave photons in a cavity is largely enhanced at the angular momentum compensation point (${T}_{A}$) when ${T}_{A}$ is distinct from the m
Publikováno v:
Journal of Applied Physics; Nov2010, Vol. 108 Issue 9, p093902, 4p, 2 Diagrams, 1 Chart, 4 Graphs
Autor:
Niala Bhagirath, Joan Subrath, Chuansheng Niu, Yan Wang, Biqi Wu, Agnes Brennan, Xiaoke Yang, Jaechul Shim, Divya Chaudhary, Clark Eid, L. Nathan Tumey, Diane H. Boschelli, Julie Lee
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 19:5829-5832
A series of 5-vinyl-3-pyridinecarbonitriles were synthesized and evaluated as PKCtheta inhibitors. The systematic optimization of 4-[(4-methyl-1H-indol-5-yl)amino]-5-[(E)-2-phenylvinyl]-3-pyridinecarbonitrile 3 resulted in the identification of compo
Autor:
Cilien Hanna, Clark Eid, Erick Honores, Weiguo Zhang, Leif M. Laakso, Ayako Yamashita, Bernard Dean Johnson, Leonard A. McDonald, Zhong Li, Weidong Ding, Dennis Powell, Jeremy I. Levin, Girija Krishnamurthy, Keiko Tabei, Jaechul Shim, Edward J. Salaski, Shabana Insaf, Lourdes Toral-Barza, Ker Yu, Tarek S. Mansour
Publikováno v:
Journal of Medicinal Chemistry. 52:2181-2184
The naturally occurring pyranonaphthoquinone (PNQ) antibiotic lactoquinomycin and related aglycones were found to be selective inhibitors of the serine-threonine kinase AKT. A set of synthetic PNQs were prepared and a minimum active feature set and p
Publikováno v:
The Journal of Organic Chemistry. 74:423-426
The pyranonaphthoquinones (+)-7-deoxyfrenolicin B and (+)-7-deoxykalafungin were synthesized in four steps using an oxa-Pictet-Spengler cyclization that directly provided the natural (3a,5)-trans-substituted dihydronaphthopyrans with high diastereose
Publikováno v:
Journal of Physics D: Applied Physics. 40:3038-3042
We found that the ultra-thin insertion of a mix of Fe and Fe oxide in the pinned layer substantially enhanced the performance of a spin valve. With the exchange bias field kept large, the giant magnetoresistance (GMR) reached 11.3%, which corresponde
Autor:
Megan A. Foley, M. Sherry Ku, Cheryl Nickerson-Nutter, Lihren Chen, Weiheng Wang, Manjunath K. Ramarao, Marina W.H. Shen, Debra G. Goodwin, Katherine L. Lee, Tam Steve Yik-Kai, Jaechul Shim, Mark L. Behnke, SooPeang Khor, John C. McKew, Xin Xu, Steven J. Kirincich, Frank Lovering, Frances Donahue, James D. Clark
Publikováno v:
Journal of Medicinal Chemistry. 50:1380-1400
The synthesis and structure-activity relationship of a series of indole inhibitors of cytosolic phospholipase A2alpha (cPLA2alpha, type IVA phospholipase) are described. Inhibitors of cPLA2alpha are predicted to be efficacious in treating asthma as w
Publikováno v:
Journal of Magnetics. 11:115-118
We successfully enhanced the performance of a spin valve by inserting an ultra-thin layer of partially oxidized Fe in the pinned and free layers. With the exchange bias field kept large, the spin valve reached a GMR of 12%, which corresponded to a 55
Autor:
Diane H. Boschelli, Vikram R. Rao, Elizabeth Murphy, Deborah Goodwin, Paul Morgan, Niala Bhagirath, Shashi Mohan, Barry Press, Jaechul Shim, Julia Shin, Marina Shen, Mengmeng Wang, Richard K. Frisbie, Eric M. Bennett, L. Nathan Tumey, Lih-Ling Lin
Publikováno v:
Bioorganicmedicinal chemistry letters. 24(9)
IRAK4 is responsible for initiating signaling from Toll-like receptors (TLRs) and members of the IL-1/18 receptor family. Kinase-inactive knock-ins and targeted deletions of IRAK4 in mice cause reductions in TLR induced pro-inflammatory cytokines and