Zobrazeno 1 - 10
of 109
pro vyhledávání: '"Jae-Seong Yang"'
Autor:
Chae Won Kang, Hyun Gyu Lim, Jaehyuk Won, Sanghak Cha, Giyoung Shin, Jae-Seong Yang, Jaeyoung Sung, Gyoo Yeol Jung
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-9 (2022)
Achieving stable production by co-culturing multiple microorganisms is often challenging due to difficulties in controlling its population. Here, the authors develop a “population guider” that can acclimate a population to higher production.
Externí odkaz:
https://doaj.org/article/c09793d8b8fd45b3ac60817ee986fcb7
Autor:
Dae-yeol Ye, Myung Hyun Noh, Jo Hyun Moon, Alfonsina Milito, Minsun Kim, Jeong Wook Lee, Jae-Seong Yang, Gyoo Yeol Jung
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
Unlike eukaryotic system, bacterial hosts lack membranous system, which is one of the limitations for efficient metabolic engineering. Here, the authors report a kinetic compartmentalization strategy to increase substrate availability from competitiv
Externí odkaz:
https://doaj.org/article/94c329eccce142b2a6717f9c5638558a
Synthetic biosensor accelerates evolution by rewiring carbon metabolism toward a specific metabolite
Autor:
Joo Yeon Seok, Yong Hee Han, Jae-Seong Yang, Jina Yang, Hyun Gyu Lim, Seong Gyeong Kim, Sang Woo Seo, Gyoo Yeol Jung
Publikováno v:
Cell Reports, Vol 36, Iss 8, Pp 109589- (2021)
Summary: Proper carbon flux distribution between cell growth and production of a target compound is important for biochemical production because improper flux reallocation inhibits cell growth, thus adversely affecting production yield. Here, using a
Externí odkaz:
https://doaj.org/article/5bbc3615f73b4f229434d91d734f7bd8
Autor:
Hyun Gyu Lim, Dong Hun Kwak, Sungwoo Park, Sunghwa Woo, Jae-Seong Yang, Chae Won Kang, Beomhee Kim, Myung Hyun Noh, Sang Woo Seo, Gyoo Yeol Jung
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
Brown macroalgae is a good candidate feedstock for biorefinery, but the major carbohydrate alginate cannot be digested by current industrial microbes. Here, the authors isolate Vibrio sp. dhg and engineer it to produce value-added biochemicals from a
Externí odkaz:
https://doaj.org/article/7e217e8ed5b64a6a84bc7a767e8509a7
Autor:
Sarah A Head, Xavier Hernandez-Alias, Jae-Seong Yang, Ludovica Ciampi, Violeta Beltran-Sastre, Antonio Torres-Méndez, Manuel Irimia, Martin H Schaefer, Luis Serrano
Publikováno v:
PLoS Biology, Vol 19, Iss 2, p e3001138 (2021)
RNA splicing is widely dysregulated in cancer, frequently due to altered expression or activity of splicing factors (SFs). Microexons are extremely small exons (3-27 nucleotides long) that are highly evolutionarily conserved and play critical roles i
Externí odkaz:
https://doaj.org/article/76df6cb1b2ea420c84a74a8d5bee3d8b
Publikováno v:
Molecular Systems Biology, Vol 16, Iss 5, Pp n/a-n/a (2020)
Abstract The C‐terminal sequence of a protein is involved in processes such as efficiency of translation termination and protein degradation. However, the general relationship between features of this C‐terminal sequence and levels of protein exp
Externí odkaz:
https://doaj.org/article/bc9fa6fff7c64bb28736e9486cf34e50
Autor:
Jae-Seong Yang, Mireia Garriga-Canut, Nele Link, Carlo Carolis, Katrina Broadbent, Violeta Beltran-Sastre, Luis Serrano, Sebastian P. Maurer
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Current methods to unveil protein–protein and protein–RNA interactions often involve long, costly procedures. Here the authors present a rapid yeast 2- and 3-hybrid screening pipeline to detect interactions within protein libraries or between pro
Externí odkaz:
https://doaj.org/article/ad8f61c4cf2f48e2a8c5190bb415f3f9
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Quantitative analysis of how DNA sequence determines transcription and translation regulation is of interest to systems and synthetic biologists. Here the authors present ELM-seq, which uses Dam activity as reporter for high-throughput analysis of pr
Externí odkaz:
https://doaj.org/article/831799865ba64682af69f894155832d0
Autor:
Dongyeop Lee, Seon Woo A An, Yoonji Jung, Yasuyo Yamaoka, Youngjae Ryu, Grace Ying Shyen Goh, Arshia Beigi, Jae-Seong Yang, Gyoo Yeol Jung, Dengke K Ma, Chang Man Ha, Stefan Taubert, Youngsook Lee, Seung-Jae V Lee
Publikováno v:
PLoS Biology, Vol 17, Iss 8, p e3000415 (2019)
Low temperatures delay aging and promote longevity in many organisms. However, the metabolic and homeostatic aspects of low-temperature-induced longevity remain poorly understood. Here, we show that lipid homeostasis regulated by Caenorhabditis elega
Externí odkaz:
https://doaj.org/article/a87c878b580e45cd83bfa66a2646930b
Autor:
Kiana Toufighi, Jae-Seong Yang, Nuno Miguel Luis, Salvador Aznar Benitah, Ben Lehner, Luis Serrano, Christina Kiel
Publikováno v:
PLoS Computational Biology, Vol 11, Iss 5, p e1004256 (2015)
The molecular details underlying the time-dependent assembly of protein complexes in cellular networks, such as those that occur during differentiation, are largely unexplored. Focusing on the calcium-induced differentiation of primary human keratino
Externí odkaz:
https://doaj.org/article/1c1ba032179a4415bed08b73a202cdae