Zobrazeno 1 - 10
of 368
pro vyhledávání: '"Jae-Ryong Kim"'
Publikováno v:
Experimental and Molecular Medicine, Vol 56, Iss 9, Pp 1967-1979 (2024)
Abstract Telomere dysfunction is a well-known molecular trigger of senescence and has been associated with various age-related diseases, including atherosclerosis. However, the mechanisms involved have not yet been elucidated, and the extent to which
Externí odkaz:
https://doaj.org/article/ff5099e2f71c4651baf4d61f8bfa4eb2
Publikováno v:
Cell Death and Disease, Vol 13, Iss 9, Pp 1-12 (2022)
Abstract Mouse double minute 1 (Mdm1) might be involved in the function and structure of centrioles and age-related retinal degeneration. However, the mechanism by which Mdm1 deficiency causes retinal degeneration remains unknown. We confirmed that t
Externí odkaz:
https://doaj.org/article/eafec684b8b74aaa94f6726b398beb2d
Autor:
Hyun-Ji Cho, Jeong-A Hwang, Eun Jae Yang, Eok-Cheon Kim, Jae-Ryong Kim, Sung Young Kim, Young Zoon Kim, Sang Chul Park, Young-Sam Lee
Publikováno v:
Cell Death and Disease, Vol 13, Iss 9, Pp 1-12 (2022)
Abstract Selective removal of senescent cells, or senolytic therapy, has been proposed to be a potent strategy for overcoming age-related diseases and even for reversing aging. We found that nintedanib, a tyrosine kinase inhibitor, selectively induce
Externí odkaz:
https://doaj.org/article/52c4c631bfb74314ac4abd789a924244
Autor:
Hyunsoo Kim, Kyunghee Lee, Jin Man Kim, Mi Yeong Kim, Jae-Ryong Kim, Han-Woong Lee, Youn Wook Chung, Hong-In Shin, Taesoo Kim, Eui-Soon Park, Jaerang Rho, Seoung Hoon Lee, Nacksung Kim, Soo Young Lee, Yongwon Choi, Daewon Jeong
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Selenoproteins containing selenium have a variety of physiological functions including redox homeostasis and thyroid hormone metabolism. Here, the authors show that RANKL-dependent repression of selenoprotein W regulates cell fusion during osteoclast
Externí odkaz:
https://doaj.org/article/46b6d838118746ec9a1733c8cc6e016a
Autor:
Ju Hee Lee, Kafi N. Ealey, Yash Patel, Navkiran Verma, Nikita Thakkar, So Young Park, Jae-Ryong Kim, Hoon-Ki Sung
Publikováno v:
iScience, Vol 25, Iss 4, Pp 104166- (2022)
Summary: The increased prevalence of obesity and metabolic diseases has heightened interest in adipose tissue biology and its potential as a therapeutic target. To better understand cellular heterogeneity and complexity of white adipose tissue (WAT),
Externí odkaz:
https://doaj.org/article/400700490d4547adb8c5b7d1528830a2
Publikováno v:
FEBS Open Bio, Vol 10, Iss 7, Pp 1316-1325 (2020)
Aging is a major risk factor for hypertension and atherosclerosis, and vascular smooth muscle cell (VSMC) senescence can promote aging‐related vascular diseases. Sirtuin‐1 (SIRT1) and AMP‐activated protein kinase (AMPK) were previously reported
Externí odkaz:
https://doaj.org/article/e884b1e35a0045f3808f314f1ffac48d
Publikováno v:
Cellular Physiology and Biochemistry, Vol 54, Iss 2, Pp 195-210 (2020)
Externí odkaz:
https://doaj.org/article/5593665149464fa09f66f99fcdc8162f
Publikováno v:
Clinical and Experimental Hypertension, Vol 41, Iss 1, Pp 20-27 (2019)
Background: Central blood pressure is closely related to the important cardiovascular intermediate end points, such as vascular hypertrophy and extent of carotid atherosclerosis. Therefore it is prudent to study correlation among central aortic blood
Externí odkaz:
https://doaj.org/article/fbc61557da6f451e8b610981f54fe4ac
Publikováno v:
PLoS ONE, Vol 15, Iss 9, p e0239976 (2020)
Cellular senescence is associated with inflammation and the senescence-associated secretory phenotype (SASP) of secreted proteins. Vascular smooth muscle cell (VSMC) expressing the SASP contributes to chronic vascular inflammation, loss of vascular f
Externí odkaz:
https://doaj.org/article/ad1c667b29a94161af94d7e5b5a781af
Publikováno v:
Clinical and Translational Radiation Oncology, Vol 10, Iss , Pp 7-12 (2018)
Background and purpose: Intravenous administration of a single amino acid-substituted chemokine CCL3 derivative named eMIP elicits the abscopal effect (an effect distal to the target), after local irradiation at a tumor-bearing site. To distinguish t
Externí odkaz:
https://doaj.org/article/755dbbf7e4b74734b4144f773cd37461