Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Jae-Kyung Nam"'
Autor:
Jae-Kyung Nam, A-Ram Kim, Seo-Hyun Choi, Ji-Hee Kim, Kyu Jin Choi, Seulki Cho, Jae Won Lee, Hyun-Jai Cho, Yoo-Wook Kwon, Jaeho Cho, Kwang Seok Kim, Joon Kim, Hae-June Lee, Tae Sup Lee, Sangwoo Bae, Hyo Jeong Hong, Yoon-Jin Lee
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Mechanisms underlying the cardiotoxicity associated with thoracic irradiation and doxorubicin treatment during anticancer therapy remain poorly understood. Here the authors show that treatment with an antibody against the L1 cell adhesion molecule in
Externí odkaz:
https://doaj.org/article/390ba1c3b7ef40a4a2315adde73d9f10
Publikováno v:
Experimental and Molecular Medicine, Vol 52, Iss 5, Pp 781-792 (2020)
Cell biology: effect of changes in cell type on disease A process of cellular conversion known as endothelial-to-mesenchymal transition (EndMT) may offer a valuable target for treating cancer and other diseases. In EndMT, the cells lining blood vesse
Externí odkaz:
https://doaj.org/article/51304f21c3434d518dd012e333844500
Autor:
Seo-Hyun Choi, A-Ram Kim, Jae-Kyung Nam, Jin-Mo Kim, Jee-Youn Kim, Haeng Ran Seo, Hae-June Lee, Jaeho Cho, Yoon-Jin Lee
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-18 (2018)
Radiotherapy is the main treatment for most cancer, but it is unclear if targeting tumour vasculature can enhance tumour radiosensitivity. Here, the authors show that tumour endothelial-mesenchymal transition after radiotherapy leads to proliferation
Externí odkaz:
https://doaj.org/article/1c8be8c45157487b80a64a318466f67b
Autor:
Yoon-Jin Lee, Jaeho Cho, Yun-Sil Lee, Young Hoon Ji, Seungwoo Park, Kyung Hwan Kim, Chang Young Lee, Yong Jin Lee, Ran Ji Yoo, Junho Jang, Hae-June Lee, Jae-Kyung Nam, Zhen-Yu Hong, Seo-Hyun Choi
Supplementary Figures 1-6. Supplementary Figure 1. Mouse models of RIPF. Supplementary Figure 2. The ocurrence of EndMT and an EMT in the development of RIPF. Supplementary Figure 3. 2-ME inhibits EMT in the development of RIPF. Supplementary Figure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::473c3a79ebdf0575c4a69ed9df71d28c
https://doi.org/10.1158/1078-0432.22456995
https://doi.org/10.1158/1078-0432.22456995
Autor:
Yoon-Jin Lee, Jaeho Cho, Yun-Sil Lee, Young Hoon Ji, Seungwoo Park, Kyung Hwan Kim, Chang Young Lee, Yong Jin Lee, Ran Ji Yoo, Junho Jang, Hae-June Lee, Jae-Kyung Nam, Zhen-Yu Hong, Seo-Hyun Choi
Purpose: Radiation-induced pulmonary fibrosis (RIPF) is a late side effect of thoracic radiotherapy. The purpose of our study was to gain further insight into the development of RIPF.Experimental Design/Results: Here, we observed that irradiation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acb38dfa6596452d58708e733e329194
https://doi.org/10.1158/1078-0432.c.6523473.v1
https://doi.org/10.1158/1078-0432.c.6523473.v1
Autor:
Yoon-Jin Lee, Jaeho Cho, Young Hoon Ji, Seungwoo Park, Hae-June Lee, Young-Bae Jin, Junho Jang, Bu-Yeo Kim, Jae-Kyung Nam, Seo-Hyun Choi
Supplementary Figures 1-12. Supplementary Figure 1. Effects of HSPB1, VEGFR1, or VEGFR2 knockdown on the EndMT in HPMECs. Supplementary Figure 2. Effects of HSPB1 knockdown or overexpression on EC-specific characteristics and Smad3 inhibitor on HSPB1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0754db439e99772e4b750c81c676d818
https://doi.org/10.1158/0008-5472.22412259
https://doi.org/10.1158/0008-5472.22412259
Autor:
Yoon-Jin Lee, Jaeho Cho, Young Hoon Ji, Seungwoo Park, Hae-June Lee, Young-Bae Jin, Junho Jang, Bu-Yeo Kim, Jae-Kyung Nam, Seo-Hyun Choi
The endothelial-to-mesenchymal transition (EndMT) contributes to cancer, fibrosis, and other pathologic processes. However, the underlying mechanisms are poorly understood. Endothelial HSP1 (HSPB1) protects against cellular stress and has been implic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7afb6008354d2083cecdb3f8a1f0dea7
https://doi.org/10.1158/0008-5472.c.6508404.v1
https://doi.org/10.1158/0008-5472.c.6508404.v1
Autor:
Yoon-Jin Lee, Jaeho Cho, Young Hoon Ji, Seungwoo Park, Hae-June Lee, Young-Bae Jin, Junho Jang, Bu-Yeo Kim, Jae-Kyung Nam, Seo-Hyun Choi
Supplementary Materials and Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35fd61f9f2962ccc1a6fb4a681983c13
https://doi.org/10.1158/0008-5472.22412256.v1
https://doi.org/10.1158/0008-5472.22412256.v1
Autor:
Yoon-Jin Lee, Jaeho Cho, Young Hoon Ji, Seungwoo Park, Hae-June Lee, Young-Bae Jin, Junho Jang, Bu-Yeo Kim, Jae-Kyung Nam, Seo-Hyun Choi
Supplementary Figure legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::435a561df55c823b981fa7c445d26695
https://doi.org/10.1158/0008-5472.22412262.v1
https://doi.org/10.1158/0008-5472.22412262.v1
Autor:
Yoon-Jin Lee, Jaeho Cho, Young Hoon Ji, Seungwoo Park, Hae-June Lee, Young-Bae Jin, Junho Jang, Bu-Yeo Kim, Jae-Kyung Nam, Seo-Hyun Choi
Supplementary Table S1. Primers information for Reverse transcription (RT)-PCR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68e2ca38de250e454d90cec88cc41d7b
https://doi.org/10.1158/0008-5472.22412253.v1
https://doi.org/10.1158/0008-5472.22412253.v1