Zobrazeno 1 - 10
of 311
pro vyhledávání: '"Jae-Kyu Roh"'
Autor:
Woo-Jin Lee, Keun-Hwa Jung, Young Jin Ryu, Soon-Tae Lee, Kyung-Il Park, Kon Chu, Manho Kim, Sang Kun Lee, Jae-Kyu Roh
Publikováno v:
PLoS ONE, Vol 15, Iss 7, p e0236473 (2020)
Cerebral white-matter hyperintensities (WMHs) on MRI is associated with reduced compliance of the cerebral arterioles. We hypothesized that an echocardiography index for left ventricular (LV) diastolic function, E/e', might reflect the cerebral arter
Externí odkaz:
https://doaj.org/article/dd4c25c65e224db687f3fb8d107d4598
Autor:
Woo-Jin Lee, Keun-Hwa Jung, Young Jin Ryu, Jeong-Min Kim, Soon-Tae Lee, Kon Chu, Manho Kim, Sang Kun Lee, Jae-Kyu Roh
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0184999 (2017)
Cerebral white matter hyperintensities (WMHs) are central MRI markers of the brain aging process, but the mechanisms for its progression remain unclear. In this study, we aimed to determine whether the baseline serum cystatin C level represented one
Externí odkaz:
https://doaj.org/article/9bc31f8071f14aad8d6d51ebc709b2aa
Autor:
Daejong Jeon, Kon Chu, Soon-Tae Lee, Keun-Hwa Jung, Jae-Jun Ban, Dong-Kyu Park, Hye-Jin Yoon, Seungmoon Jung, Hyunwoo Yang, Byung Sun Kim, Ji Ye Choi, So Hee Kim, Jeong-Min Kim, Chong-Hyun Won, Manho Kim, Sang Kun Lee, Jae-Kyu Roh
Publikováno v:
Neurobiology of Disease, Vol 54, Iss , Pp 414-420 (2013)
A recent study suggested that a cell-free extract of human adipose stem cells (hASCs-E) has beneficial effects on neurological diseases by modulating the host environment. Here, we investigated the effects of hASCs-E in several experimental models of
Externí odkaz:
https://doaj.org/article/0351a21c160b40939461e13d372e1e8b
Autor:
Keun-Hwa Jung, Kon Chu, Soon-Tae Lee, Jae-Jun Bahn, Daejong Jeon, Jin-Hee Kim, Soyun Kim, Chong-Hyun Won, Manho Kim, Sang Kun Lee, Jae-Kyu Roh
Publikováno v:
Neurobiology of Disease, Vol 41, Iss 2, Pp 489-497 (2011)
Tissue pericytes respond to injury, and support vascular and tissue regeneration. The presence of pericytes in the circulation may provide an attractive framework for tissue regeneration. Here, we detected multipotent pericyte-like cells in the circu
Externí odkaz:
https://doaj.org/article/793e777764dd4403af5702f89933f41a
Autor:
Dong-In Sinn, Se-Jeong Kim, Kon Chu, Keun-Hwa Jung, Soon-Tae Lee, Eun-Cheol Song, Jeong-Min Kim, Dong-Kyu Park, Sang Kun Lee, Manho Kim, Jae-Kyu Roh
Publikováno v:
Neurobiology of Disease, Vol 26, Iss 2, Pp 464-472 (2007)
The modification of histone N-terminal tails by acetylation or deacetylation can alter the interaction between histones and DNA, and thus regulate gene expression. Recent experiments have demonstrated that valproic acid (VPA), a well-known anti-epile
Externí odkaz:
https://doaj.org/article/a673de7d70e74205afdd58639e35b159
Autor:
Sung Won Youn, Keun-Hwa Jung, Kon Chu M.D., Ph.D., Jong-Young Lee, Soon-Tae Lee, Jae-Jun Bahn, Dong-Kyu Park, Jung-Suk Yu, So-Yun Kim, Manho Kim, Sang Kun Lee, Moon-Hee Han, Jae-Kyu Roh M.D., Ph.D.
Publikováno v:
Cell Transplantation, Vol 24 (2015)
Stem cell therapy is currently being studied with a view to rescuing various neurological diseases. Such studies require not only the discovery of potent candidate cells but also the development of methods that allow optimal delivery of those candida
Externí odkaz:
https://doaj.org/article/7813aecd45114bf3ba49f0c4f935c0b0
Autor:
Keun-Hwa Jung, Kon Chu, Soon-Tae Lee, Juhyun Kim, Dong-In Sinn, Jeong-Min Kim, Dong-Kyu Park, Jung-Ju Lee, Seung U. Kim, Manho Kim, Sang Kun Lee, Jae-Kyu Roh
Publikováno v:
Neurobiology of Disease, Vol 23, Iss 2, Pp 237-246 (2006)
Recent evidences suggest key roles of abnormal neurogenesis and astrogliosis in the pathogenesis of epilepsy. Alterations in the microenvironment of the stem cell, such as microglial activation and cyclooxygenase-2 induction may cause ectopic neuroge
Externí odkaz:
https://doaj.org/article/f0ab3fd1cad14d06b151a21a2b3175c9
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e95277 (2014)
BACKGROUND: The relationship between whole spectrum of Ejection fraction (EF) and cardioembolic stroke (CES) outcome has not been fully described yet. Notably, it remains unclear whether borderline EF (41∼49%) is related with poor outcome after CES
Externí odkaz:
https://doaj.org/article/7aa9258344dd430f905c5aaa88bc6efd
Autor:
Jeong-Min Kim, Soon-Tae Lee, Kon Chu, Keun-Hwa Jung, Jin Hee Kim, Jung-Suk Yu, Soyun Kim, So Hee Kim, Dong-Kyu Park, Jangsup Moon, Jaejun Ban, Manho Kim, Sang Kun Lee, Jae-Kyu Roh
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e97946 (2014)
Intracerebral hemorrhage (ICH) is a devastating neurological disease with a grave prognosis. We evaluated microRNA (miRNA) expression after ICH and evaluated Let7c as a therapeutic target. We harvested hemorrhagic brain 24 hours after collagenase ind
Externí odkaz:
https://doaj.org/article/d41a767694064161b4d06b236e2496ac
Autor:
Yong-Won Shin, Keun-Hwa Jung, Jeong-Min Kim, Young Dae Cho, Soon-Tae Lee, Kon Chu, Manho Kim, Sang Kun Lee, Moon Hee Han, Jae-Kyu Roh
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e100569 (2014)
BACKGROUND: Intracranial aneurysm (IA) is significantly more prevalent in patients with coarctation of the aorta or bicuspid aortic valve than in the general population, suggesting a common pathophysiology connecting IA and aortopathy. Here, we analy
Externí odkaz:
https://doaj.org/article/c3bcee7f698b40f1a8dfc625e2f1bfe9