Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Jae-K Ryu"'
Publikováno v:
The Korean Health & Fundamental Medical Science Society. 14:115-121
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7997f24e3d25eb980021dd3f7b51ff4
https://doi.org/10.37152/kmhs.2021.14.2.115
https://doi.org/10.37152/kmhs.2021.14.2.115
Autor:
Hans Lassmann, Rosa Meza-Acevedo, Jae K. Ryu, Belinda S. Cabriga, Reuben Thomas, Katerina Akassoglou, Mark A. Petersen, Zhaoqi Yan, Yungui Zhou, Eric A. Bushong, Reshmi Tognatta, Anke Meyer-Franke, Mario Merlini, Mark H. Ellisman, Andrew S. Mendiola, Abinaya Muthusamy
Publikováno v:
Brain : a journal of neurology, vol 144, iss 8
Brain
Brain
Extrinsic inhibitors at sites of blood–brain barrier disruption and neurovascular damage contribute to remyelination failure in neurological diseases. However, therapies to overcome the extrinsic inhibition of remyelination are not widely available
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8585c10d6c53364230dc6a3fe244c9e9
https://doi.org/10.1093/brain/awab106
https://doi.org/10.1093/brain/awab106
Autor:
Reuben Thomas, Terry Dean, Mark A. Petersen, Matthias G. Haberl, Jae K. Ryu, Victoria A. Rafalski, Andrew S. Mendiola, Eric A. Bushong, Keunyoung Kim, Daniel Naranjo Sampson, Elif G. Sozmen, Reshmi Tognatta, Rosa Meza Acevedo, Zhaoqi Yan, Shaun R. Coughlin, Mark H. Ellisman, Pamela E. Rios Coronado, Belinda S. Cabriga, Jorge J. Palop, Sophia Bardehle, Mario Merlini, Katerina Akassoglou, Matthew Madany, Keran Ma
Publikováno v:
Nature Neuroscience. 24:19-23
Microglial surveillance is a key feature of brain physiology and disease. Here, we found that Gi-dependent microglial dynamics prevent neuronal network hyperexcitability. By generating MgPTX mice to genetically inhibit Gi in microglia, we show that s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d558dcdacc49cb06330157f8ecf84e06
https://doi.org/10.1038/s41593-020-00756-7
https://doi.org/10.1038/s41593-020-00756-7
Autor:
Sonia Franciosi, Jae K. Ryu, Yaein Shim, Austin Hill, Colum Connolly, Michael R. Hayden, James G. McLarnon, Blair R. Leavitt
Publikováno v:
Neurobiology of Disease, Vol 45, Iss 1, Pp 438-449 (2012)
Central nervous system (CNS) inflammatory processes including microglial activation have been implicated in the pathogenesis of neurodegenerative diseases such as Huntington Disease (HD). We report age-dependent changes in striatal microglial morphol
Externí odkaz:
https://doaj.org/article/6eef76b7952049a68fe79fff51876834
Autor:
Jae K. Ryu, James G. McLarnon
Publikováno v:
Neurobiology of Disease, Vol 29, Iss 2, Pp 254-266 (2008)
Injection of Aβ1-42 peptide into rat hippocampus has been found to induce microglial reactivity and perturbed vasculature in an animal model of inflamed Alzheimer’s disease (AD) brain. We report the anti-angiogenic and anti-inflammatory compound,
Externí odkaz:
https://doaj.org/article/86e5172158c446d3a3532ec05a81824a
Autor:
Yixin Liu, Reuben Thomas, Jae K. Ryu, Rosa Meza Acevedo, Kara L. Lynch, Alexander R. Pico, Zhaoqi Yan, Warner C. Greene, Yusuke Matsui, Katerina Akassoglou, Renaud Schuck, Ekram Helmy, Elif G. Sozmen, Karuna Dixit, Collin M. Spencer, Thomas J. Deerinck, Mark H. Ellisman, Scott S. Zamvil, Mauricio Montano
Publikováno v:
bioRxiv
Blood clots are a central feature of coronavirus disease-2019 (COVID-19) and can culminate in pulmonary embolism, stroke, and sudden death. However, it is not known how abnormal blood clots form in COVID-19 or why they occur even in asymptomatic and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::156b4c98978be7a408054685f1681fae
https://doi.org/10.1101/2021.10.12.464152
https://doi.org/10.1101/2021.10.12.464152
Publikováno v:
Neurobiology of Disease, Vol 20, Iss 2, Pp 550-561 (2005)
The effects of the peripheral benzodiazepine receptor (PBR) ligand, PK11195, were investigated in the rat striatum following the administration of quinolinic acid (QUIN). Intrastriatal QUIN injection caused an increase of PBR expression in the lesion
Externí odkaz:
https://doaj.org/article/619896753fcd4e0a8e0209e547395b51
Autor:
Jae K Ryu, Jean Kim, Sung J Cho, Kozo Hatori, Astushi Nagai, Hyun B Choi, Min C Lee, James G McLarnon, Seung U Kim
Publikováno v:
Neurobiology of Disease, Vol 16, Iss 1, Pp 68-77 (2004)
We have investigated the effectiveness of transplantation of human neural stem cells into adult rat striatum prior to induction of striatal damage with the mitochondrial toxin 3-nitropropionic acid (3-NP). Systemic 3-NP administration caused widespre
Externí odkaz:
https://doaj.org/article/076889e72c2444c988bb1f1ce3b80349
Publikováno v:
Neurobiology of Disease, Vol 14, Iss 2, Pp 181-193 (2003)
One week after intranigral injection of thrombin resulted in a dose-dependent loss of dopaminergic neurons (20–78%) in the rat substantia nigra (SN), as evidenced by tyrosine hydroxylase (TH) immunohistochemistry. This cell death was accompanied by
Externí odkaz:
https://doaj.org/article/c9ab59bfc3e34f318aeb18701ebdceef
Publikováno v:
Neurobiology of Disease, Vol 12, Iss 2, Pp 121-132 (2003)
Metabolic impairment of neurons has been implicated in several neurological disorders, but it is not at present known whether such metabolic impairment has deleterious effects on microglia, the phagocytic cells of the central nervous system (CNS). In
Externí odkaz:
https://doaj.org/article/e311e42de53247ccb80b87b2309d7bcb