Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Jae-Il Roh"'
Publikováno v:
Laboratory Animal Research, Vol 34, Iss 4, Pp 264-269 (2018)
Abstract Cell cycle dysfunction can cause severe diseases, including neurodegenerative disease and cancer. Mutations in cyclin-dependent kinase inhibitors controlling the G1 phase of the cell cycle are prevalent in various cancers. Mice lacking the t
Externí odkaz:
https://doaj.org/article/47a92ac7627241169ce7af323ea82c87
Autor:
HyunJeong Lee, Joo-Il Kim, Jin-Sung Park, Jae-il Roh, Jaehoon Lee, Byeong-Cheol Kang, Han-Woong Lee
Publikováno v:
Laboratory Animal Research, Vol 34, Iss 4, Pp 279-287 (2018)
Abstract Placenta specific 8 (PLAC8, also known as ONZIN) is a multi-functional protein that is highly expressed in the intestine, lung, spleen, and innate immune cells, and is involved in various diseases, including cancers, obesity, and innate immu
Externí odkaz:
https://doaj.org/article/957deaf895b54107b2ed9e49ffc391f4
Publikováno v:
PLoS ONE, Vol 15, Iss 8, p e0236881 (2020)
PIERCE1, p53 induced expression 1 in Rb null cells, is a novel p53 target involved in the DNA damage response and cell cycle in mice. These facts prompted us to study the function of PIERCE1 with respect to p53-associated pathophysiology of cancer in
Externí odkaz:
https://doaj.org/article/4f0de87a29a2464f8a5a5186739751de
Autor:
Jae-Il Roh, Yujin Kim, Jahyun Oh, Yunmi Kim, Jeehyun Lee, Jaehoon Lee, Kyung-Hee Chun, Han-Woong Lee
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0193182 (2018)
Autophagy is systematically regulated by upstream factors and nutrients. Recent studies reported that telomerase and hexokinase 2 [HK2) regulate autophagy through mTOR and that telomerase has the capacity to bind to the HK2 promoter. However, the mol
Externí odkaz:
https://doaj.org/article/4d5e6bf2183d46eb83faf651e13119e0
Autor:
Jae-il Roh, Cheolho Cheong, Young Hoon Sung, Jeehyun Lee, Jaewon Oh, Beom Seob Lee, Jong-Eun Lee, Yong Song Gho, Duk-Kyung Kim, Chan Bae Park, Ji Hyun Lee, Jae Woon Lee, Seok-Min Kang, Han-Woong Lee
Publikováno v:
Cell Reports, Vol 8, Iss 4, Pp 991-998 (2014)
Dilated cardiomyopathy (DCM) is a progressive heart disease characterized by left ventricular dilation and contractile dysfunction. Although many candidate genes have been identified with mouse models, few of them have been shown to be associated wit
Externí odkaz:
https://doaj.org/article/d401c969a040446ebeb4e851f86fb35c
Autor:
Young-Hoon Sung, Seungeon Lee, Yaechan Song, Do Young Hyeon, Jae-Hoon Lee, Yujin Kim, Jae-il Roh, Hye Jeong Kim, Bomin Park, Yonghwan Kim, Taewook Nam, Jahyun Oh, Han Woong Lee, Daehee Hwang, Sushil Devkota
Publikováno v:
Oncogene
KRAS-mutant non-small cell lung cancer (NSCLC) is a major lung cancer subtype that leads to many cancer-related deaths worldwide. Although numerous studies on KRAS-mutant type NSCLC have been conducted, new oncogenic or tumor suppressive genes need t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::074976032f0b810b62c65820edc1c7b1
https://doi.org/10.1038/s41388-020-01399-5
https://doi.org/10.1038/s41388-020-01399-5
Autor:
Sungsook Yu, Su Cheong Yeom, Tae Wook Nam, Ki Taek Nam, Young Jin, Jae-Hoon Lee, Ji-Young Cha, Yoon Ki Kim, Jeong Pil Han, Jae Il Roh, Han Woong Lee
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports
Scientific Reports
Engineered nucleases are widely used for creating frameshift or nonsense mutations in the target genes to eliminate gene functions. The resulting mRNAs carrying premature termination codons can be eliminated by nonsense-mediated mRNA decay. However,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::058f546159429bd9fd972b090da44352
http://link.springer.com/article/10.1038/s41598-020-61154-4
http://link.springer.com/article/10.1038/s41598-020-61154-4
Autor:
Jae Il Roh, Woojin Chung
Publikováno v:
International Journal of Advanced Robotic Systems, Vol 8, Iss 2, Pp 114-121 (2011)
Passive trailer systems provide a variety of advantages in delivery and transportation applications. The transportation capacity of the truck with multiple trailers can be increased in proportion to the number of trailers. The cost of the car with tr
Externí odkaz:
https://doaj.org/article/ad7ce3849b0941bdb2052fbc3e50678f
Publikováno v:
Biochemical and Biophysical Research Communications. 514:1087-1092
Etoposide-induced 2.4 kb transcript (EI24, also known as PIG8) is a p53 target gene involved in cell growth suppression and apoptosis and known to be frequently altered in human cancers. Although EI24 expression is decreased in various cancers and is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b95adda056d918aeff94dcd6c7f7fee
https://doi.org/10.1016/j.bbrc.2019.04.186
https://doi.org/10.1016/j.bbrc.2019.04.186
Autor:
Han Woong Lee, Byeongcheol Kang, Hyunjeong Lee, Jae-il Roh, Jae-Hoon Lee, Jin-Sung Park, Joo-Il Kim
Publikováno v:
Laboratory Animal Research, Vol 34, Iss 4, Pp 279-287 (2018)
Placenta specific 8 (PLAC8, also known as ONZIN) is a multi-functional protein that is highly expressed in the intestine, lung, spleen, and innate immune cells, and is involved in various diseases, including cancers, obesity, and innate immune defici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73005f9d52e3cd62f329e82615ab3959
http://link.springer.com/article/10.5625/lar.2018.34.4.279
http://link.springer.com/article/10.5625/lar.2018.34.4.279