Zobrazeno 1 - 10
of 197
pro vyhledávání: '"Jae Yong Choi"'
Autor:
Jae Hun Ahn, Min Hwan Kim, Kyongkyu Lee, Keumrok Oh, Hyunwoo Lim, Hee Seup Kil, Soon Jeong Kwon, Jae Yong Choi, Dae Yoon Chi, Yong Jin Lee
Publikováno v:
EJNMMI Research, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Background N-(3-fluoropropyl)-2β-carboxymethoxy-3β-(4-iodophenyl) nortropane (FP-CIT), the representative cocaine derivative used in dopamine transporter imaging, is a promising biomarker, as it reflects the severity of Parkinson’s disea
Externí odkaz:
https://doaj.org/article/1439753c4ac34c389c845621de74365d
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract The effective dose represents the overall internal radiation exposure to the whole body when exposed to radiation sources. This study aims to compare conventional and software-aided methods to derive the effective dose. In the present study,
Externí odkaz:
https://doaj.org/article/76627551bb854bd895db10f907bd1eef
Autor:
Se Jong Oh, Namhun Lee, Kyung Rok Nam, Kyung Jun Kang, Kyo Chul Lee, Yong Jin Lee, Jeong-Ho Seok, Jae Yong Choi
Publikováno v:
Frontiers in Psychiatry, Vol 14 (2023)
IntroductionTraumatic events in early life have a deleterious effect on the development of normal brain developments, which may be a cause of various psychiatric disorders in adulthood. Most prior studies focused on molecular biological aspects, and
Externí odkaz:
https://doaj.org/article/d4ebc67695a844c7975b29d4dfdf6d5f
Autor:
Se Jong Oh, Namhun Lee, Kyung Rok Nam, Kyung Jun Kang, Sang Jin Han, Kyo Chul Lee, Yong Jin Lee, Jae Yong Choi
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Externí odkaz:
https://doaj.org/article/615780a6835a4cfb9f56c84eb67262e3
Autor:
Se Jong Oh, Namhun Lee, Kyung Rok Nam, Kyung Jun Kang, Sang Jin Han, Kyo Chul Lee, Yong Jin Lee, Jae Yong Choi
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
This study aimed to investigate how amyloid pathology affects the functional aspects of neurotransmitter systems in Alzheimer’s disease. APPswe/PS2 mice (21 months of age) and wild-type (WT) mice underwent positron emission tomography (PET) and mag
Externí odkaz:
https://doaj.org/article/d57f6a8a2edb49b8a4df12ed2e1c0d33
Autor:
Hee Jin Kim, Hanna Cho, Seongbeom Park, Hyemin Jang, Young Hoon Ryu, Jae Yong Choi, Seung Hwan Moon, Seung Jun Oh, Minyoung Oh, Duk L. Na, Chul Hyoung Lyoo, Eun-Joo Kim, William W. Seeley, Jae Seung Kim, Kyung Chan Choi, Sang Won Seo
Publikováno v:
BMC Neurology, Vol 19, Iss 1, Pp 1-5 (2019)
Abstract Background THK5351 and flortaucipir tau ligands have high affinity for paired helical filament tau, yet diverse off-target bindings have been reported. Recent data support the hypothesis that THK5351 binds to monoamine oxidase B (MAO-B) expr
Externí odkaz:
https://doaj.org/article/55e39400a9a446d586233e4cbbcdb407
Publikováno v:
Journal of Movement Disorders, Vol 11, Iss 1, Pp 1-12 (2018)
In recent years, several radiotracers that selectively bind to pathological tau proteins have been developed. Evidence is emerging that binding patterns of in vivo tau positron emission tomography (PET) studies in Alzheimer’s disease (AD) patients
Externí odkaz:
https://doaj.org/article/26c3c31117224934ac91b3c10863ee9c
Autor:
Ye Ji Jeong, Yeonghoon Son, Hye-Jin Park, Se Jong Oh, Jae Yong Choi, Young-Gyu Ko, Hae-June Lee
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 17, p 9374 (2021)
Global aging has led to growing health concerns posed by Alzheimer’s disease (AD), the most common type of dementia. Aripiprazole is an atypical FDA-approved anti-psychotic drug with potential against AD. To investigate its therapeutic effects on A
Externí odkaz:
https://doaj.org/article/dbbf30b7d997426aa03cb4e52235dc9e
Autor:
Kyung Jun Kang, Se Jong Oh, Kyung Rok Nam, Heesu Ahn, Ji-Ae Park, Kyo Chul Lee, Jae Yong Choi
Publikováno v:
Journal of Imaging, Vol 7, Iss 3, p 43 (2021)
Background: Micro-positron emission tomography (micro-PET), a small-animal dedicated PET system, is used in biomedical studies and has the quantitative imaging capabilities of radiotracers. A single-bed system, commonly used in micro-PET, is laboriou
Externí odkaz:
https://doaj.org/article/16c76f1e19864783b1bf17e32b03c8d1
Autor:
Yeonghoon Son, Ye Ji Jeong, Na-Rae Shin, Se Jong Oh, Kyung Rok Nam, Hyung-Do Choi, Jae Yong Choi, Hae-June Lee
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 15, p 5553 (2020)
Alzheimer’s disease (AD) is a progressive neurodegenerative disease. In this study, to investigate the effect of microglial elimination on AD progression, we administered PLX3397, a selective colony-stimulating factor 1 receptor inhibitor, to the m
Externí odkaz:
https://doaj.org/article/fd75aae2213741f9b65a228f97253c1e