Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Jae Yang Kong"'
Autor:
Sang-Hyun Lee, YoungSoo Kim, Hye Yun Kim, Young Hoon Kim, Maeng Sup Kim, Jae Yang Kong, Mun-Han Lee, Dong Jin Kim, Young Gil Ahn
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e95733 (2014)
Alzheimer's disease is an irreversible neurodegenerative disorder that is characterized by the abnormal aggregation of amyloid-β into neurotoxic oligomers and plaques. Although many disease-modifying molecules are currently in Alzheimer clinical tri
Externí odkaz:
https://doaj.org/article/71619b57b0bf44738486e164ad55a88f
Autor:
Lee, Sunghou, Kim, Gun-Do, Park, Woo-Kyu, Cho, Heeyeong, Byung Ho Lee, Yoo, Sung-eun, Jae Yang Kong
Publikováno v:
In Journal of Pharmacological and Toxicological Methods 2006 53(3):242-247
Autor:
Seong Jin Lee, Ha-Young Kim, Jong-Yeon Hwang, Heeyeong Cho, Woo Kyu Park, Jae-Yang Kong, Young-Dae Gong, Doohyun Lee, Dae Young Jeong, Gee-Hyung Lee, Tae-Ho Lee
Publikováno v:
Bulletin of the Korean Chemical Society. 35:2385-2390
Autor:
Gildon Choi, Daeyoung Jeong, Heeyeong Cho, Mu-Hyun Jin, Seong Jin Lee, Jae Yang Kong, Tae-Hoon Jung, Hojeong Kim, Woo-Kyu Park
Publikováno v:
Archives of Pharmacal Research
The interaction of stem cell factor (SCF) with its cognate receptor c-Kit is closely associated with the survival and maturation of melanocytes. To investigate novel depigmentation agents, we screened 2,000 plant extracts for c-Kit inhibitors to iden
Autor:
Mi Kyeong Lee, Ji-Yeong Bae, Dong Hoon Lee, Kyeong Jae Cho, Sun-Young Han, Yoon Seok Lee, Eun Ju Jeong, Jae Yang Kong, Haeng Soon Lee, Mi Jeong Ahn
Publikováno v:
Biomolecules & Therapeutics
Rumex acetosa is a perennial herb that is widely distributed across eastern Asia. Although the hot water extract of R. acetosa has been used to treat gastritis or gastric ulcers as a folk medicine, no scientific report exists for the use of this plan
Autor:
Seong Jin Lee, Jae Yang Kong, Chang-Seon Myung, Ge Hyeong Lee, Hee-Jong Lim, Heeyeong Cho, Woo-Kyu Park, Hyoseok Yi, Ji-Yeong Lee
Publikováno v:
Neurochemical Research. 36:2083-2090
Abnormal accumulation of β-amyloid (Aβ) is the main characteristic of Alzheimer’s disease (AD) brain and Aβ peptides are generated from proteolytic cleavages of amyloid precursor protein (APP) by β-site APP-converting enzyme 1 (BACE1) and prese
Autor:
Sangjin Kang, Gildon Choi, Jae Yang Kong, Seong Jin Lee, Daeyoung Jeong, Heeyeong Cho, Hojeong Kim, Woo-Kyu Park
Publikováno v:
Phytotherapy Research. 24:308-312
In search of novel antipigmentation agents, a set of 3,840 compounds with natural-like synthetic or natural origin were screened against Kit (stem cell factor receptor). Emodin from the seed of Cassia tora and baicalin from Scutellariae radix showed
Autor:
Gyu Hwan Yon, Young Sup Kim, Woo-Kyu Park, Shi Yong Ryu, Chun Whan Choi, Kyung Sik Hong, Yeon Hee Choi, Jae Yang Kong, Dae Seok Yoo
Publikováno v:
Planta Medica. 74:1405-1408
A new isoflavone, neocorylin ( 1) was isolated from the seeds extract of Psoralea corylifolia L. (Fabaceae), together with eight known constituents ( 2 - 9), i. e., bakuchiol ( 2), psoralen ( 3), bavachromene ( 4), isobavachromene ( 5), bavachalcone
Autor:
Ae Nim Pae, Ji Yeon Kim, Hyewhon Rhim, Eun A Yoo, Jae Yang Kong, Hea-Young Park Choo, Juhee Yoon, Woo-Kyu Park
Publikováno v:
Bioorganic & Medicinal Chemistry. 16:5405-5412
Twenty-four compounds of 4-methoxy-N-[3-(4-substituted phenyl-piperazine-1-yl)propyl] benzene sulfonamides and N-[3-(4-substituted phenyl-piperazine-1-yl)propyl] naphthyl sulfonamides were prepared and evaluated as 5-HT(7) receptor antagonists. Most
Autor:
Hyang-Ok Jo, Yasuo Konishi, Young-Sik Jung, Jong-Pyung Kim, No-Sang Park, Jae-Yang Kong, Tae-Souk Kang, Woo-Kyu Park
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 18:1663-1667
A series of 3,5-dialkoxy-4-hydroxycinnamamides 6 and 7 was synthesized, and their antioxidant activity was assessed using the thiobarbituric acid reactive substance (TBARS) assay. Interestingly, cinnamamides with longer alkoxy groups on the C-3 and C