Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Jae Su Moon"'
Autor:
Rui Si, Jody Tori O. Cabrera, Atsumi Tsuji-Hosokawa, Rui Guo, Makiko Watanabe, Lei Gao, Yun Sok Lee, Jae-Su Moon, Brian T. Scott, Jian Wang, Anthony W. Ashton, Jaladanki N. Rao, Jian-Ying Wang, Jason X.-J. Yuan, Ayako Makino
Publikováno v:
JCI Insight, Vol 6, Iss 21 (2021)
Patients with diabetes with coronary microvascular disease (CMD) exhibit higher cardiac mortality than patients without CMD. However, the molecular mechanism by which diabetes promotes CMD is poorly understood. RNA-binding protein human antigen R (Hu
Externí odkaz:
https://doaj.org/article/6276e505da664ccaa86691d1f879b040
Autor:
Jae-Su Moon, Flavia Franco da Cunha, Jin Young Huh, Alexander Yu Andreyev, Jihyung Lee, Sushil K. Mahata, Felipe C.G. Reis, Chanond A. Nasamran, Yun Sok Lee
Publikováno v:
JCI Insight, Vol 6, Iss 20 (2021)
Macrophage proinflammatory activation is an important etiologic component of the development of insulin resistance and metabolic dysfunction in obesity. However, the underlying mechanisms are not clearly understood. Here, we demonstrate that a mitoch
Externí odkaz:
https://doaj.org/article/ae17e38f7a7047aa88e356bab333a21a
Autor:
Minwoo Kim, Hee Cho, Seung-Hoon Lee, Woo-Jung Park, Jeong-Min Kim, Jae-Su Moon, Geon-Woo Kim, Wooseong Lee, Hae-Gwang Jung, Jeong-Sun Yang, Jang-Hoon Choi, Joo-Yeon Lee, Sung Soon Kim, Jong-Won Oh
Publikováno v:
Emerging Microbes and Infections, Vol 9, Iss 1, Pp 2714-2726 (2020)
ABSTRACTThe MERS-CoV isolated during the 2015 nosocomial outbreak in Korea showed distinctive differences in mortality and transmission patterns compared to the prototype MERS-CoV EMC strain belonging to clade A. We established a BAC-based reverse ge
Externí odkaz:
https://doaj.org/article/bcdf5cb3555f4f9a9415960f9a8f7480
Autor:
Matthew Riopel, Jae-Su Moon, Gautam K. Bandyopadhyay, Seohee You, Kevin Lam, Xiao Liu, Tatiana Kisseleva, David Brenner, Yun Sok Lee
Publikováno v:
Molecular Metabolism, Vol 41, Iss , Pp 101039- (2020)
Objective: Recent evidence indicates that inhibition of prolyl hydroxylase domain (PHD) proteins can exert beneficial effects to improve metabolic abnormalities in mice and humans. However, the underlying mechanisms are not clearly understood. This s
Externí odkaz:
https://doaj.org/article/06c284378d004c56b6f14b5961bc43b3
Autor:
Wooseong Lee, Seung-Hoon Lee, Minwoo Kim, Jae-Su Moon, Geon-Woo Kim, Hae-Gwang Jung, In Hwang Kim, Ji Eun Oh, Hi Eun Jung, Heung Kyu Lee, Keun Bon Ku, Dae-Gyun Ahn, Seong-Jun Kim, Kun-Soo Kim, Jong-Won Oh
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Quorum sensing signaling molecules are known to be critical determinants in bacterial pathogenesis. Here the authors show the quorum sensing molecule cFP from Vibrio vulnificus inhibits the RIG-I mediated antiviral interferon response and enhances su
Externí odkaz:
https://doaj.org/article/547b377f526943aa911360a9ae058cac
Publikováno v:
J Virol
Hepatitis delta virus (HDV) is a defective satellite virus that uses hepatitis B virus (HBV) envelope proteins to form its virions and infect hepatocytes via the HBV receptors. Concomitant HDV/HBV infection continues to be a major health problem, wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b101280b9d1b9d3d1dba5880e385f3f8
https://doi.org/10.1128/jvi.01124-22
https://doi.org/10.1128/jvi.01124-22
Publikováno v:
Diabetes, vol 71, iss 7
Diabetes
Diabetes
In obesity, increased mitochondrial metabolism with the accumulation of oxidative stress leads to mitochondrial damage and β-cell dysfunction. In particular, β-cells express antioxidant enzymes at relatively low levels and are highly vulnerable to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db8a624d97f032b89613550d5c9c12e1
https://escholarship.org/uc/item/0kz0c5dw
https://escholarship.org/uc/item/0kz0c5dw
In obesity, increased mitochondrial metabolism with the accumulation of oxidative stress leads to mitochondrial damage and beta cell dysfunction. In particular, beta cells express anti-oxidant enzymes at relatively low levels and are highly vulnerabl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::485c525235e6e10d31bf5cdb1184ee43
https://doi.org/10.2337/figshare.19607331
https://doi.org/10.2337/figshare.19607331
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Significance HBV infections are the leading cause of chronic hepatitis and carry the risk of liver cirrhosis and cancer. The HBV life cycle is perpetuated by an RNA intermediate termed pregenomic RNA (pgRNA), which is encapsidated by the viral core p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd70fede243960a1587da1f41f6402ea
https://doi.org/10.1073/pnas.2120485119
https://doi.org/10.1073/pnas.2120485119
Autor:
Jae-Su Moon, Seung-Hoon Lee, Eun-Jung Kim, Hee Cho, Wooseong Lee, Geon-Woo Kim, Hyun-Ji Park, Seung-Woo Cho, Choongho Lee, Jong-Won Oh
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0146710 (2016)
The hepatitis C virus (HCV) internal ribosome entry site (IRES) that directs cap-independent viral translation is a primary target for small interfering RNA (siRNA)-based HCV antiviral therapy. However, identification of potent siRNAs against HCV IRE
Externí odkaz:
https://doaj.org/article/01b432130869487b8cffc0bbcf981c90