Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Jae Ryong, Lim"'
Autor:
Min Jeong Kim, Gee Euhn Choi, Chang Woo Chae, Jae Ryong Lim, Young Hyun Jung, Jee Hyeon Yoon, Ji Yong Park, Ho Jae Han
Publikováno v:
Cell Death and Disease, Vol 14, Iss 2, Pp 1-15 (2023)
Abstract The physiological crosstalk between glucocorticoid and melatonin maintains neuronal homeostasis in regulating circadian rhythms. However, the stress-inducing level of glucocorticoid triggers mitochondrial dysfunction including defective mito
Externí odkaz:
https://doaj.org/article/422194e5168342678d3b895f3dab2f57
Autor:
Young Hyun Jung, Chang Woo Chae, Gee Euhn Choi, Him Cha Shin, Jae Ryong Lim, Han Seung Chang, Joonmo Park, Ji Hyeon Cho, Mo Ran Park, Hyun Jik Lee, Ho Jae Han
Publikováno v:
Journal of Biomedical Science, Vol 29, Iss 1, Pp 1-17 (2022)
Abstract Background Androgenetic alopecia (AGA) is a genetic disorder caused by dihydrotestosterone (DHT), accompanied by the senescence of androgen-sensitive dermal papilla cells (DPCs) located in the base of hair follicles. DHT causes DPC senescenc
Externí odkaz:
https://doaj.org/article/2088e48484e64be4b2de3229faf06845
Autor:
Jae Ryong Lim, Chang Woo Chae, Ji Yong Park, Young Hyun Jung, Jee Hyeon Yoon, Min Jeong Kim, Hyun Jik Lee, Gee Euhn Choi, Ho Jae Han
Publikováno v:
Neurobiology of Disease, Vol 177, Iss , Pp 106009- (2023)
Heavy alcohol consumption causes neuronal cell death and cognitive impairment. Neuronal cell death induced by ethanol may result from increased production of the sphingolipid metabolite ceramide. However, the molecular mechanisms of neuronal cell dea
Externí odkaz:
https://doaj.org/article/941482575f4f4fcab6d790891c5eef29
Autor:
Jun Sung Kim, Young Hyun Jung, Hyun Jik Lee, Chang Woo Chae, Gee Euhn Choi, Jae Ryong Lim, Seo Yihl Kim, Joo Eun Lee, Ho Jae Han
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-14 (2021)
Abstract Background Retarded wound healing in patients with obesity contributes to a risk of complications associated with vascular insufficiency and oxidative stress. The high cholesterol levels of patients with obesity are associated with apoptosis
Externí odkaz:
https://doaj.org/article/303fd4dcf5934b5eac40c8ebc69dc733
Autor:
Gee Euhn Choi, Hyun Jik Lee, Chang Woo Chae, Ji Hyeon Cho, Young Hyun Jung, Jun Sung Kim, Seo Yihl Kim, Jae Ryong Lim, Ho Jae Han
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Stress-induced glucocorticoids cause mitochondrial damage in neurons, but they are not cleared by mitophagy. Here, the authors show that glucocorticoids inhibit NIX-dependent basal mitophagy, contributing to neurodegeneration in a mouse model that ca
Externí odkaz:
https://doaj.org/article/2cac894c75774d089073e5f07a58c03c
Autor:
Jae Ryong Lim, Hyun Jik Lee, Young Hyun Jung, Jun Sung Kim, Chang Woo Chae, Seo Yihl Kim, Ho Jae Han
Publikováno v:
Cell Communication and Signaling, Vol 18, Iss 1, Pp 1-19 (2020)
Abstract Background Neurodegeneration is a representative phenotype of patients with chronic alcoholism. Ethanol-induced calcium overload causes NOD-like receptor protein 3 (NLRP3) inflammasome formation and an imbalance in mitochondrial dynamics, cl
Externí odkaz:
https://doaj.org/article/b5445ae6f24f44bb87b0f879d4fc02ad
Autor:
Ji Young Oh, Gee Euhn Choi, Hyun Jik Lee, Young Hyun Jung, So Hee Ko, Chang Woo Chae, Jun Sung Kim, Seo Yihl Kim, Jae Ryong Lim, Chang-Kyu Lee, Ho Jae Han
Publikováno v:
Cellular Physiology and Biochemistry, Vol 46, Iss 5, Pp 1749-1767 (2018)
Background/Aims: Glucose plays an important role in stem cell fate determination and behaviors. However, it is still not known how glucose contributes to the precise molecular mechanisms responsible for stem cell migration. Thus, we investigate the e
Externí odkaz:
https://doaj.org/article/67e1d3a3966a42c0bffaaa229830f52e
Autor:
Ji Hyeon Cho, Ho Jae Han, Jae Ryong Lim, Young Hyun Jung, Seo Yihl Kim, Chang Woo Chae, Gee Euhn Choi, Jun Sung Kim, Hyun Jik Lee
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Nature Communications
Nature Communications
Stress-induced glucocorticoids disturb mitochondrial bioenergetics and dynamics; however, instead of being removed via mitophagy, the damaged mitochondria accumulate. Therefore, we investigate the role of glucocorticoids in mitophagy inhibition and s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fde2492e5cfa979646a340c92ecacff
https://doaj.org/article/2cac894c75774d089073e5f07a58c03c
https://doaj.org/article/2cac894c75774d089073e5f07a58c03c
Autor:
Ji Hyeon Cho, Sei-Jung Lee, Jae Ryong Lim, Young Hyun Jung, Chang Woo Chae, Jun Sung Kim, Seo Yihl Kim, Jee Hyeon Yoon, Hyun Jik Lee, Ho Jae Han, Gee Euhn Choi
Publikováno v:
Cell Death Differ
Hyperglycemia in diabetes mellitus (DM) patients is a causative factor for amyloidogenesis and induces neuropathological changes, such as impaired neuronal integrity, neurodegeneration, and cognitive impairment. Regulation of mitochondrial calcium in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36f37619689269735acda2453fb0eb40
https://doi.org/10.1038/s41418-020-0593-1
https://doi.org/10.1038/s41418-020-0593-1
Autor:
Chang Woo Chae, Ho Jae Han, Jun Sung Kim, Seo Yihl Kim, Jae Ryong Lim, Young Hyun Jung, Hyun Jik Lee, Je Kyung Seong, In Koo Hwang, Gee Euhn Choi
Publikováno v:
Br J Pharmacol
Background and purpose Although diabetes mellitus (DM) is an important risk factor for Alzheimer's disease (AD), the detailed mechanism(s) by which DM regulates amyloid β (Aβ) processing is still unclear. The longer residence time of amyloid precur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc2c1d66ebb859aaf749fa79d6b0b25b
https://doi.org/10.1111/bph.15131
https://doi.org/10.1111/bph.15131