Zobrazeno 1 - 10
of 280
pro vyhledávání: '"Jae K Lee"'
Publikováno v:
Neural Regeneration Research, Vol 13, Iss 4, Pp 684-691 (2018)
Schwann cell transplantation is a promising therapy for the treatment of spinal cord injury (SCI) and is currently in clinical trials. In our continuing efforts to improve Schwann cell transplantation strategies, we sought to determine the combined e
Externí odkaz:
https://doaj.org/article/1e662998ae344c1ebd76fa88a026e66e
Autor:
Suvra Nath, Jose C. Martínez Santamaría, Yu-Hsuan Chu, James S. Choi, Pasquale Conforti, Jia-Di Lin, Roman Sankowski, Lukas Amann, Christos Galanis, Kexin Wu, Sachin S. Deshpande, Andreas Vlachos, Marco Prinz, Jae K. Lee, Christian Schachtrup
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract After a stroke, the neurogenic response from the subventricular zone (SVZ) to repair the brain is limited. Microglia, as an integral part of the distinctive SVZ microenvironment, control neural stem / precursor cell (NSPC) behavior. Here, we
Externí odkaz:
https://doaj.org/article/7aaae40ae2e04412a7b85444f8236258
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0207325 (2018)
[This corrects the article DOI: 10.1371/journal.pone.0204100.].
Externí odkaz:
https://doaj.org/article/1614555deeee41759d99ab375bca9748
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0204100 (2018)
One of the biggest challenges in analyzing high throughput omics data in biological studies is extracting information that is relevant to specific biological mechanisms of interest while simultaneously restricting the number of false positive finding
Externí odkaz:
https://doaj.org/article/5e9007ee73d946109b5e20d29394f083
Autor:
Amber R Hackett, Jae K Lee
Publikováno v:
Frontiers in Neurology, Vol 7 (2016)
NG2 cells, also known as oligodendrocyte progenitor cells, are located throughout the central nervous system and serve as a pool of progenitors to differentiate into oligodendrocytes. In response to spinal cord injury, NG2 cells increase their prolif
Externí odkaz:
https://doaj.org/article/0d01411bb9e04ae9a53664c4eb2b3712
Autor:
Timothy E Newhook, Edik M Blais, James M Lindberg, Sara J Adair, Wenjun Xin, Jae K Lee, Jason A Papin, J Thomas Parsons, Todd W Bauer
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e105631 (2014)
Currently, prognostication for pancreatic ductal adenocarcinoma (PDAC) is based upon a coarse clinical staging system. Thus, more accurate prognostic tests are needed for PDAC patients to aid treatment decisions.Affymetrix gene expression profiling w
Externí odkaz:
https://doaj.org/article/bd1e56f5edfe469eb69c4306e672b877
Autor:
Youngchul Kim, Saketh R Guntupalli, Sun J Lee, Kian Behbakht, Dan Theodorescu, Jae K Lee, Jennifer R Diamond
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e86532 (2014)
Aggressive tumors such as epithelial ovarian cancer (EOC) are highly heterogeneous in their therapeutic response, making it difficult to improve overall response by using drugs in unselected patients. The goal of this study was to retrospectively, bu
Externí odkaz:
https://doaj.org/article/d06e7305a1324131bba139f19c68ac87
Autor:
Dustin M Walters, Jayme B Stokes, Sara J Adair, Edward B Stelow, Cheryl A Borgman, Bryce T Lowrey, Wenjun Xin, Edik M Blais, Jae K Lee, Jason A Papin, J Thomas Parsons, Todd W Bauer
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77065 (2013)
BACKGROUND:Relevant preclinical models that recapitulate the key features of human pancreatic ductal adenocarcinoma (PDAC) are needed in order to provide biologically tractable models to probe disease progression and therapeutic responses and ultimat
Externí odkaz:
https://doaj.org/article/366a8db7440643c59e739a86aa547bd9
Publikováno v:
Neural Regeneration Research, Vol 11, Iss 2, Pp 0-0 (2016)
Externí odkaz:
https://doaj.org/article/4438df717b6e469cbb1a477883f2b45d
Autor:
J Stuart Ferriss, Youngchul Kim, Linda Duska, Michael Birrer, Douglas A Levine, Christopher Moskaluk, Dan Theodorescu, Jae K Lee
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e30550 (2012)
Despite advances in radical surgery and chemotherapy delivery, ovarian cancer is the most lethal gynecologic malignancy. Standard therapy includes treatment with platinum-based combination chemotherapies yet there is no biomarker model to predict the
Externí odkaz:
https://doaj.org/article/b4e517ff81be439084a9c96d1bf1fb21