Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Jae Hyun Jang"'
Autor:
Doo Eun Choi, Jun Wan Shin, Sophia Zeng, Eun Pyo Hong, Jae-Hyun Jang, Jacob M Loupe, Vanessa C Wheeler, Hannah E Stutzman, Ben Kleinstiver, Jong-Min Lee
Publikováno v:
eLife, Vol 12 (2024)
An expanded CAG repeat in the huntingtin gene (HTT) causes Huntington’s disease (HD). Since the length of uninterrupted CAG repeat, not polyglutamine, determines the age-at-onset in HD, base editing strategies to convert CAG to CAA are anticipated
Externí odkaz:
https://doaj.org/article/be3156c656d24edfa4a721019c3ab21e
Publikováno v:
Animal Cells and Systems, Vol 27, Iss 1, Pp 403-412 (2023)
ABSTRACTColorectal cancer (CRC) is the most common malignant tumor and one of the leading causes of cancer-related death worldwide. Oncogene KRAS is a commonly mutated in CRC and plays crucial roles in the colorectal tumorigenesis. Emerging evidence
Externí odkaz:
https://doaj.org/article/701425cc4f944f00bd9d52a804b6c3fa
Publikováno v:
Biomedical Science Letters. 28:237-246
Autor:
Doo Eun Choi, Jun Wan Shin, Sophia Zeng, Eun Pyo Hong, Jae-Hyun Jang, Jacob M. Loupe, Vanessa C. Wheeler, Hannah E. Stutzman, Benjamin P. Kleinstiver, Jong-Min Lee
Publikováno v:
bioRxiv
An expanded CAG repeat in the huntingtin gene (HTT) causes Huntington’s disease (HD). Since the length of uninterrupted CAG repeat, not polyglutamine, determines the age-at-onset in HD, base editing strategies to convert CAG to CAA are anticipated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f95978ca0d623b50e7eb2b21c91a6b50
https://doi.org/10.1101/2023.04.28.538700
https://doi.org/10.1101/2023.04.28.538700
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1866:329-336
Inflammatory lipid mediators play various roles in colorectal cancer progression through complex pathways. However, the mechanism by which lipoxygenase-derived inflammatory lipid mediators contribute to colorectal cancer progression remains elusive.
Publikováno v:
Biochemical Engineering Journal. 142:135-144
The current study was aimed to investigate the synthesis and self-assembly of cellulose nanofibrils in in vitro environment through intermediate phase analysis and compare with the microbial cell system. The presence and stability of cellulose syntha
Autor:
Donghwan Park, Jae Hyun Jang, Hye Jin You, Guen soo Park, Jae Hong Kim, Dong Wook Kwak, Jae In Park, Dae Yeul Yu
Publikováno v:
Experimental & Molecular Medicine
Although lung cancer is the leading cause of cancer-related deaths worldwide and KRAS is the most frequently mutated oncogene in lung cancer cases, the mechanism by which KRAS mutation drives lung cancer has not been fully elucidated. Here, we report
Autor:
Shaukat Khan, Muhammad Ikram, Muhammad Israr, Salman Ul Islam, Joong Kon Park, Muhammad Wajid Ullah, Mazhar Ul-Islam, Sik Yoon, Jae Hyun Jang
Publikováno v:
International Journal of Biological Macromolecules. 117:1200-1210
This study reports the fabrication of porogen-induced, surface-modified, 3-dimensionally microporous regenerated bacterial cellulose (rBC)/gelatin (3DMP rBC/G) scaffolds for skin regeneration applications. Round shaped gelatin microspheres (GMS), fab
Publikováno v:
BMB Reports
Triple-negative breast cancer (TNBC) is considered to be a notorious type of cancer due to its aggressive metastatic potential and poor prognosis. Recent evidence suggests that BLT2, a low-affinity LTB4 receptor is critically associated with the phen
Publikováno v:
Journal of the Korean Institute of Illuminating and Electrical Installation Engineers. 32:30-35