Zobrazeno 1 - 10
of 418
pro vyhledávání: '"Jae H Park"'
Publikováno v:
PLoS ONE, Vol 19, Iss 6, p e0305696 (2024)
In Drosophila coordinated proliferation of two neural stem cells, neuroblasts (NB) and neuroepithelial (NE) cells, is pivotal for proper larval brain growth that ultimately determines the final size and performance of an adult brain. The larval brain
Externí odkaz:
https://doaj.org/article/b576fd81785f40f09d6fe7d7e8af800b
Autor:
Daniel J DeAngelo, Yi Lin, Roch Houot, Marion Subklewe, Petra C Schuberth, Michael R Bishop, Nicolas Boissel, Dimitrios Tzachanis, Jae H Park, Monique C Minnema, Thibaut Leguay, Mehrdad Abedi, Bijal D Shah, Ryan D Cassaday, Olalekan O Oluwole, Aaron C Logan, Max S Topp, Kristen M O'Dwyer, Martha L Arellano, Maria R Baer, Gary J Schiller, William G Wierda, Patrick J Stiff, Deepa Jeyakumar, Daqin Mao, Sabina Adhikary, Lang Zhou, Rita Damico Khalid, Armin Ghobadia
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 8 (2023)
Background Brexucabtagene autoleucel (brexu-cel) is an autologous anti-CD19 chimeric antigen receptor (CAR) T-cell therapy approved in the USA for adults with relapsed or refractory (R/R) B-cell acute lymphoblastic leukemia (B-ALL) and in the Europea
Externí odkaz:
https://doaj.org/article/6d2eb34905f7419ca7f3a7451cc9953e
Autor:
Michel Sadelain, Eric L Smith, Jae H Park, Renier J Brentjens, Ahmet Dogan, Sébastien Monette, Isabelle Riviere, M Lia Palomba, David Qualls, Shenon Sethi, Mikhail Roshal, Brigitte Senechal, Xiuyan Wang
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 2 (2022)
Externí odkaz:
https://doaj.org/article/c11af96b477b456f8d202023e1bc31b9
Publikováno v:
ESMO Open, Vol 5, Iss 5 (2020)
With recent prospective clinical trials that used paediatric regimens with multiple doses of pegylated form of asparaginase (PEG asparaginase) in adults reporting significantly improved survival compared with historical data with regimens that used l
Externí odkaz:
https://doaj.org/article/d4f46fb9746a491f89d5c22af34ef267
Autor:
Johan A Kers, Anthony W DeFusco, Jae H Park, Jin Xu, Mark E Pulse, William J Weiss, Martin Handfield
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0197467 (2018)
Lantibiotics continue to offer an untapped pipeline for the development of novel antibiotics. We report here the discovery of a novel lantibiotic for the treatment of C. difficile infection (CDI). The leads were selected from a library of over 300 mu
Externí odkaz:
https://doaj.org/article/8576e0e2154a45a69a25cf4db2f4e489
Autor:
Erin Munkácsy, Maruf H Khan, Rebecca K Lane, Megan B Borror, Jae H Park, Alex F Bokov, Alfred L Fisher, Christopher D Link, Shane L Rea
Publikováno v:
PLoS Genetics, Vol 12, Iss 7, p e1006133 (2016)
Mitochondrial dysfunction underlies numerous age-related pathologies. In an effort to uncover how the detrimental effects of mitochondrial dysfunction might be alleviated, we examined how the nematode C. elegans not only adapts to disruption of the m
Externí odkaz:
https://doaj.org/article/52b06c2aa0d54ce68d32d730b18b2ad3
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e87062 (2014)
Impaired ethanol metabolism can lead to various alcohol-related health problems. Key enzymes in ethanol metabolism are alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH); however, neuroendocrine pathways that regulate the activities of the
Externí odkaz:
https://doaj.org/article/daad72d971ac4d85ba63c27ddd36ce8f
Publikováno v:
PLoS ONE, Vol 3, Iss 3, p e1896 (2008)
The bHLH transcription factor DIMMED has been associated with the differentiation of peptidergic cells in Drosophila. However, whether all Drosophila peptidergic cells express DIMM, and the extent to which all DIMM cells are peptidergic, have not bee
Externí odkaz:
https://doaj.org/article/a43226617de04b84aa9661c4049b9204
Autor:
Ibrahim Aldoss, Bijal D. Shah, Jae H. Park, Lori Muffly, Aaron C. Logan, Patrick Brown, Wendy Stock, Elias J. Jabbour
Publikováno v:
American Journal of Hematology. 98:666-680
Autor:
Armin Ghobadi, Michael Slade, Hagop Kantarjian, Julio Alvarenga, Ibrahim Aldoss, Kahee A. Mohammed, Elias Jabbour, Rawan Faramand, Bijal Shah, Frederick Locke, Warren Fingrut, Jae H. Park, Nicholas J. Short, Feng Gao, Geoffrey L. Uy, Peter Westervelt, John F. DiPersio, Richard E. Champlin, Monzr M. Al Malki, Farhad Ravandi, Partow Kebriaei
Publikováno v:
Blood. 140:2101-2112
Historically, Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL) has been associated with poor outcomes, and allogeneic hematopoietic cell transplantation (allo-HCT) is recommended in first complete remission (CR1). However, in