Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Jae Cheal Yoo"'
Autor:
Dong-Gyu Kim, Jae Cheal Yoo, Eunju Kim, Young-Sun Lee, Oleg V. Yarishkin, Da Yong Lee, Kun Ho Lee, Seong-Geun Hong, Eun Mi Hwang, Jae-Yong Park
Publikováno v:
Endocrinology and Metabolism, Vol 29, Iss 2, Pp 185-194 (2014)
BackgroundMitochondrial trans-2-enoyl-CoA reductase (MECR) is involved in mitochondrial synthesis of fatty acids and is highly expressed in mitochondria. MECR is also known as nuclear receptor binding factor-1, which was originally reported with yeas
Externí odkaz:
https://doaj.org/article/5eac8350162a428f83bd348e0b015642
Autor:
Taehyeok Hwang, Hyo Jung Lee, Woo Sung Park, Dong-Min Kang, Mi-Jeong Ahn, Hyonok Yoon, Jae Cheal Yoo, Dong Kyu Moon, Dong Kyun Woo
Publikováno v:
International Journal of Medical Sciences. 19:1131-1137
Autor:
Taehyeok, Hwang, Hyo Jung, Lee, Woo Sung, Park, Dong-Min, Kang, Mi-Jeong, Ahn, Hyonok, Yoon, Jae Cheal, Yoo, Dong Kyu, Moon, Dong Kyun, Woo
Publikováno v:
International journal of medical sciences. 19(7)
Although melanogenesis is a defense mechanism against ultraviolet (UV)-induced skin damage, abnormally excessive melanin production causes pigmentation disorders. Tyrosinase, as a key factor for melanin synthesis, plays an important role in inducing
Autor:
Boah Lee, Hye Young Choi, Dong Kyun Woo, Nammi Park, Jae Yong Park, Yeong In Choe, Jae Cheal Yoo
Publikováno v:
Biochemical and biophysical research communications. 533(3)
We previously demonstrated that CPNE1 induces neuronal differentiation and identified two binding proteins of CPNE1 (14-3-3γ and Jab1) as potential regulators of CPNE1-mediated neuronal differentiation in hippocampal progenitor cells. To better unde
Publikováno v:
Biomolecules & Therapeutics
The phosphorylation of JNK is known to induce insulin resistance in insulin target tissues. The inhibition of JNK-JIP1 interaction, which interferes JNK phosphorylation, becomes a potential target for drug development of type 2 diabetes. To discover
Autor:
Eun Hye Byun, Jae Cheal Yoo, Jung Yeon Park, Jae Yong Park, Nammi Park, Dong Kun Lee, Eunmi Hwang, Young-Sun Lee, Dawon Kang, Yeon Ju Bae, Jaehee Han, Seong Geun Hong
Publikováno v:
Pflügers Archiv - European Journal of Physiology. 470:1449-1458
Transient receptor-potential, cation channel, subfamily M, member 4 (TRPM4) channels regulate a variety of physiological and pathological processes; however, their roles as functional channels under diverse conditions remain unclear. In this study, c
Publikováno v:
Biochemical and Biophysical Research Communications. 497:424-429
Copine1 (CPNE1), has tandem C2 domains and an A domain. We previously demonstrated that CPNE1 directly induces neuronal differentiation via Protein kinase B (AKT) phosphorylation in the hippocampal progenitor cell line, HiB5. To better understand its
Autor:
Jae Cheal Yoo, Gwan-Su Yi, Sang-Ok Lee, Seung-Wook Chi, Jeong A. Min, Abdullateef Nashed, Boah Lee
Publikováno v:
Biochemical and biophysical research communications. 514(2)
Irinotecan is a strong anticancer drug whose mechanism of action has been reported only for the inhibition of DNA topoisomerase I (Topo I) through its active metabolite SN-38. In this study, we present a new mechanism of Irinotecan which inhibits the
Autor:
Jae Yong Park, Nammi Park, Jae Cheal Yoo, Eun Mi Hwang, Hye Young Choi, Young-Sun Lee, Seong Geun Hong
Publikováno v:
Biochemical and Biophysical Research Communications. 454:228-233
Copine1 (CPNE1) has tandem C2 domains and an A domain and is known as a calcium-dependent membrane-binding protein that regulates signal transduction and membrane trafficking. We previously demonstrated that CPNE1 directly induces neuronal differenti
Autor:
Jae-Ran Lee, Jae Yong Park, Jae Cheal Yoo, Jun Young Heo, Gwan-Su Yi, Tae Hwan Kim, Soo Eun Sung, Da Yong Lee, Nam Soon Kim
Publikováno v:
Biochemical and biophysical research communications. 495(1)
Copine 1 (CPNE1) is a well-known phospholipid binding protein in plasma membrane of various cell types. In brain cells, CPNE1 is closely associated with AKT signaling pathway, which is important for neural stem cell (NSC) functions during brain devel