Zobrazeno 1 - 10
of 234
pro vyhledávání: '"Jae Bong Park"'
Publikováno v:
Antioxidants, Vol 12, Iss 12, p 2090 (2023)
Inflammation plays a crucial role in tumorigenesis, primarily mediated by NF-κB. RhoA GTPases are instrumental in regulating the activation of NF-κB. Specifically, the phosphorylation of Tyrosine 42 on RhoA ensures the activation of NF-κB by direc
Externí odkaz:
https://doaj.org/article/da44ca0daf6342d1a7c3a91f529e983c
Autor:
Shohel Mahmud, Amir Hamza, Yoon-Beom Lee, Jung-Ki Min, Rokibul Islam, Oyungerel Dogsom, Jae-Bong Park
Publikováno v:
Biomolecules, Vol 14, Iss 1, p 6 (2023)
Cell migration is a crucial contributor to metastasis, a critical process associated with the mortality of cancer patients. The initiation of metastasis is triggered by epithelial–mesenchymal transition (EMT), along with the changes in the expressi
Externí odkaz:
https://doaj.org/article/257783ef3a374bb9b472c25894bcba79
Publikováno v:
Antioxidants, Vol 12, Iss 6, p 1186 (2023)
The development of treatment strategies for human corneal endothelial cells (hCECs) disease is necessary because hCECs do not regenerate in vivo due to the properties that are similar to senescence. This study is performed to investigate the role of
Externí odkaz:
https://doaj.org/article/af55e544fdc74ff2be0bb999a2e87ac6
Autor:
Beom-Seok Kang, Bo-Young Choi, A-Ra Kho, Song-Hee Lee, Dae-Ki Hong, Min-Kyu Park, Si-Hyun Lee, Chang-Juhn Lee, Hyeun-Wook Yang, Seo-Young Woo, Se-Wan Park, Dong-Yeon Kim, Jae-Bong Park, Won-Suk Chung, Sang-Won Suh
Publikováno v:
Antioxidants, Vol 12, Iss 2, p 491 (2023)
Ischemic stroke is caused by insufficient blood flow to the brain. Astrocytes have a role in bidirectionally converting pyruvate, generated via glycolysis, into lactate and then supplying it to neurons through astrocyte–neuron lactate shuttle (ANLS
Externí odkaz:
https://doaj.org/article/7f8a85d289014eb3965be6d2c7abed8f
Autor:
Jae-Gyu Kim, Shohel Mahmud, Jung Ki Min, Yoon-Beom Lee, Hyunbin Kim, Dong-Chul Kang, Hwee-Seon Park, Jihye Seong, Jae-Bong Park
Publikováno v:
Redox Biology, Vol 40, Iss , Pp 101842- (2021)
In the Wnt canonical pathway, Wnt3A has been known to stabilize β-catenin. In the non-canonical Wnt signaling pathway, Wnt is known to activate Rho GTPases. The correlation between canonical and non-canonical pathways by Wnt signaling, however, has
Externí odkaz:
https://doaj.org/article/c5072cfca2804dc194eb41024555b432
Autor:
Abu Jubayer Hossain, Rokibul Islam, Jae-Gyu Kim, Oyungerel Dogsom, Kim Cuong Cap, Jae-Bong Park
Publikováno v:
Biomedicines, Vol 10, Iss 6, p 1256 (2022)
Insulin potently promotes cell proliferation and anabolic metabolism along with a reduction in blood glucose levels. Pyruvate dehydrogenase (PDH) plays a pivotal role in glucose metabolism. Insulin increase PDH activity by attenuating phosphorylated
Externí odkaz:
https://doaj.org/article/3806bae581f94ac1b6b30306c3c2f71b
Publikováno v:
Biomedicines, Vol 10, Iss 5, p 1112 (2022)
Src, a non-receptor tyrosine kinase, was first discovered as a prototype oncogene and has been shown to critical for cancer progression for a variety of tissues. Src activity is regulated by a number of post-translational modifications in response to
Externí odkaz:
https://doaj.org/article/045ed86afbb24d82a2e37b0c54e045c3
Publikováno v:
Applied Sciences, Vol 12, Iss 8, p 3948 (2022)
Numerical model updating using the data measured from the actual structure is required in order to minimize the error between the initial numerical model and the actual structure. Field load tests, which are conducted in order to assess the condition
Externí odkaz:
https://doaj.org/article/75e754d861ea4c40a2b6a3a84a4a1da2
Publikováno v:
Structures. 47:299-312
Autor:
Kim Cuong Cap, Yeon-Joo Jung, Bo Young Choi, Seung Jae Hyeon, Jae-Gyu Kim, Jung-Ki Min, Rokibul Islam, Abu Jubayer Hossain, Won-Suk Chung, Sang Won Suh, Hoon Ryu, Jae-Bong Park
Publikováno v:
Redox Biology, Vol 32, Iss , Pp - (2020)
Both the accumulation of Amyloid-β (Aβ) in plaques and phosphorylation of Tau protein (p-Tau) in neurofibrillary tangles have been identified as two major symptomatic features of Alzheimer's disease (AD). Despite of critical role of Aβ and p-Tau i
Externí odkaz:
https://doaj.org/article/a20a025e20e145a7a6a2007e76c4dfa2