Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Jadwiga Paszkowska"'
Autor:
Daniel Zakowiecki, Peter Edinger, Tobias Hess, Jadwiga Paszkowska, Marcela Staniszewska, Svitlana Romanova, Grzegorz Garbacz
Publikováno v:
Pharmaceutics, Vol 15, Iss 9, p 2224 (2023)
Tableting of biomolecules is a challenging formulation phase due to their sensitivity to various process parameters, such as compression pressure, process dynamics, or the temperature generated. In the present study, pancreatin was employed as a mode
Externí odkaz:
https://doaj.org/article/38d592463c8a43c78d90e7b5ba9b2153
Autor:
Marcela Staniszewska, Michał Romański, Sebastian Polak, Grzegorz Garbacz, Justyna Dobosz, Daria Myslitska, Svitlana Romanova, Jadwiga Paszkowska, Dorota Danielak
Publikováno v:
Pharmaceutics, Vol 15, Iss 8, p 2056 (2023)
Gastric mechanical stress often impacts drug dissolution from solid oral dosage forms, but in vitro experiments cannot recreate the substantial variability of gastric motility in a reasonable time. This study, for the first time, combines a novel dis
Externí odkaz:
https://doaj.org/article/7aa2c9715a5f4ab893bf9b66cdb98730
Autor:
Krzysztof Cal, Barbara Mikolaszek, Tobias Hess, Markos Papaioannou, Joanna Lenik, Patrycja Ciosek-Skibińska, Helene Wall, Jadwiga Paszkowska, Svitlana Romanova, Grzegorz Garbacz, Daniel Zakowiecki
Publikováno v:
Pharmaceuticals, Vol 16, Iss 2, p 242 (2023)
Sprinkle formulations represent an interesting concept of medicinal products aimed at the steadily growing population of patients suffering from swallowing difficulties (dysphagia). In the present work, immediate-release sprinkle MUPS (multiple-unit
Externí odkaz:
https://doaj.org/article/2614d5c6acba4493b2fa560e21d027ab
Publikováno v:
Farmacja Polska, Vol 76, Iss 4, Pp 210-221 (2020)
The first and an essential step of medication’s path inside the human body is a dissolution of an active pharmaceutical ingridient. A dissolution of oral dosage forms occurs as a result of physicochemical and mechanical stresses which are found in
Externí odkaz:
https://doaj.org/article/7bc889da58514c4db653020ae7faf990
Autor:
Daniel Zakowiecki, Maja Frankiewicz, Tobias Hess, Krzysztof Cal, Maciej Gajda, Justyna Dabrowska, Bartlomiej Kubiak, Jadwiga Paszkowska, Marcela Wiater, Dagmara Hoc, Grzegorz Garbacz, Dorota Haznar-Garbacz
Publikováno v:
Pharmaceutics, Vol 13, Iss 6, p 805 (2021)
Novel calcium phosphate-based starter pellets were used to develop a biphasic-release multiple-unit pellet system (MUPS) with diclofenac sodium as a model drug in the form of hard gelatin capsules. For comparative purposes, corresponding formulations
Externí odkaz:
https://doaj.org/article/38db019efbd34125be646d5d35787b60
Autor:
Ewelina Juszczyk, Kamil Kisło, Paweł Żero, Ewa Tratkiewicz, Maciej Wieczorek, Jadwiga Paszkowska, Grzegorz Banach, Marcela Wiater, Dagmara Hoc, Grzegorz Garbacz, Jaroslaw Sczodrok, Dorota Danielak
Publikováno v:
Pharmaceutics, Vol 13, Iss 6, p 804 (2021)
Sustained-release (SR) formulations may appear advantageous in first-in-human (FIH) study of innovative medicines. The newly developed SR matrix tablets require prolonged maintenance of API concentration in plasma and should be reliably assessed for
Externí odkaz:
https://doaj.org/article/2c388692b34c45d5a425d96b77ef910b
Autor:
Ilona Wandzik, Wiesław Szeja, Urszula Nawrot, Tadeusz Bieg, Katarzyna Kral, Jadwiga Paszkowska
Publikováno v:
Molecules, Vol 18, Iss 7, Pp 8018-8027 (2013)
New derivatives of uridine which contain a b-ketoenol motif were synthesized, characterized and biologically tested. Synthesized compounds 1–4 showed no activity against bovine milk β-1,4-galactosyltransferase I at concentrations up to 2.0 mM and
Externí odkaz:
https://doaj.org/article/3eb8b60487e5430db9d388d5e49e86ec
Autor:
Dorota Danielak, Jadwiga Paszkowska, Marcela Staniszewska, Grzegorz Garbacz, Anna Terlecka, Bartłomiej Kubiak, Michał Romański
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 186:132-143
Autor:
Michał Romański, Marcela Staniszewska, Jadwiga Paszkowska, Justyna Dobosz, Svitlana Romanova, Jarosław Pieczuro, Michał Kątny, Dagmara Roznerska, Janusz Szczepański, Michał Schraube, Monika Renn-Hojan, Ewa Puk, Oksana Hrem, Grzegorz Garbacz, Dorota Danielak
Publikováno v:
International Journal of Pharmaceutics. 641:123061
Publikováno v:
Farmacja Polska, Vol 76, Iss 4, Pp 210-221 (2020)
The first and an essential step of medication’s path inside the human body is a dissolution of an active pharmaceutical ingridient. A dissolution of oral dosage forms occurs as a result of physicochemical and mechanical stresses which are found in