Zobrazeno 1 - 10
of 542
pro vyhledávání: '"Jadwiga A, Wedzicha"'
Autor:
Mario Cazzola, Clive P. Page, Jadwiga A. Wedzicha, Bartolome R. Celli, Antonio Anzueto, Maria Gabriella Matera
Publikováno v:
Respiratory Research, Vol 24, Iss 1, Pp 1-13 (2023)
Abstract Background Oxidative stress and persistent airway inflammation are thought to be important contributors to the development of chronic obstructive pulmonary disease (COPD). This review summarizes the evidence for targeting oxidative stress an
Externí odkaz:
https://doaj.org/article/6bba8031d0d8401ab5e9891c5158f396
Autor:
Lydia J. Finney, Stefan Avey, Dexter Wiseman, Anthony Rowe, Matthew J. Loza, Patrick Branigan, Christopher S. Stevenson, Frédéric Baribaud, Jadwiga A. Wedzicha, Ioannis Pandis, Gavin C. Donaldson
Publikováno v:
ERJ Open Research, Vol 9, Iss 6 (2023)
Background Early and accurate identification of acute exacerbations of COPD may lead to earlier treatment and prevent hospital admission. Electronic diaries have been developed for symptom monitoring and accelerometers to monitor activity. However, i
Externí odkaz:
https://doaj.org/article/22593049a77b49ed87596d43e4afecae
Autor:
Judith M Vonk, Torben Sigsgaard, Kian Fan Chung, Lies Lahousse, Maarten van den Berge, Jadwiga A Wedzicha, Judith Garcia-Aymerich, Anne Lindberg, Claus Vogelmeier, Helena Backman, Eva Rönmark, Ian M Adcock, Peter Alter, Alvar Agustí, Gavin C Donaldson, Guy G Brusselle, Rosa Faner, Howraman Meteran, Ahmed Edris, Nazanin Zounemat Kermani, Xander Bertels, Nuria Olvera
Publikováno v:
BMJ Open Respiratory Research, Vol 10, Iss 1 (2023)
Background The prevalence and clinical profile of asthma with airflow obstruction (AO) remain uncertain. We aimed to phenotype AO in population- and clinic-based cohorts.Methods This cross-sectional multicohort study included adults ≥50 years from
Externí odkaz:
https://doaj.org/article/4246d986f53a452a9373d730efc8e7de
Autor:
Augusta S. Beech, Simon Lea, Umme Kolsum, Zhang Wang, Bruce E. Miller, Gavin C. Donaldson, Jadwiga A. Wedzicha, Christopher E. Brightling, Dave Singh
Publikováno v:
Respiratory Research, Vol 21, Iss 1, Pp 1-13 (2020)
Abstract Background There is evidence that bacterial colonisation in chronic obstructive pulmonary disease (COPD) is associated with increased neutrophilic airway inflammation. This study tested the hypothesis that different bacterial phyla and speci
Externí odkaz:
https://doaj.org/article/5a2293924db94ec4a0b39990a3eb85c8
Autor:
Dave Singh, Jadwiga A. Wedzicha, Salman Siddiqui, Alberto de la Hoz, Wenqiong Xue, Helgo Magnussen, Marc Miravitlles, James D. Chalmers, Peter M. A. Calverley
Publikováno v:
Respiratory Research, Vol 21, Iss 1, Pp 1-10 (2020)
Abstract Background Chronic obstructive pulmonary disease (COPD) is characterised by progressive airflow limitation and chronic inflammation. Predicting exacerbations of COPD, which contribute to disease progression, is important to guide preventativ
Externí odkaz:
https://doaj.org/article/1428768bef3040f9ab20ab19592abf68
Autor:
Koirobi Haldar, Leena George, Zhang Wang, Vijay Mistry, Mohammadali Yavari Ramsheh, Robert C. Free, Catherine John, Nicola F. Reeve, Bruce E. Miller, Ruth Tal-Singer, Adam J. Webb, Anthony J. Brookes, Martin D. Tobin, Dave Singh, Gavin C. Donaldson, Jadwiga A. Wedzicha, James R. Brown, Michael R. Barer, Christopher E. Brightling
Publikováno v:
Respiratory Research, Vol 21, Iss 1, Pp 1-12 (2020)
Abstract Background Airway bacterial dysbiosis is a feature of chronic obstructive pulmonary disease (COPD). However, there is limited comparative data of the lung microbiome between healthy smokers, non-smokers and COPD. Methods We compared the 16S
Externí odkaz:
https://doaj.org/article/73014c336784438f822b8bbf3948c801
Autor:
Alexander J. Mackay, Konstantinos Kostikas, Nicolas Roche, Stefan-Marian Frent, Petter Olsson, Pascal Pfister, Pritam Gupta, Francesco Patalano, Donald Banerji, Jadwiga A. Wedzicha
Publikováno v:
Respiratory Research, Vol 21, Iss 1, Pp 1-9 (2020)
Abstract Background COPD is a heterogeneous disease and patients may respond differently to therapies depending on baseline symptom burden. Methods This post-hoc analysis from the 52-week FLAME study investigated the impact of baseline symptom burden
Externí odkaz:
https://doaj.org/article/be3ea100e1364513b51d798c89cd9982
Autor:
Gabriella H. Long, Thomas Southworth, Umme Kolsum, Gavin C. Donaldson, Jadwiga A. Wedzicha, Christopher E. Brightling, Dave Singh
Publikováno v:
Respiratory Research, Vol 21, Iss 1, Pp 1-4 (2020)
Abstract Blood eosinophils are a predictive biomarker of inhaled corticosteroid response in chronic obstructive pulmonary disease (COPD). We investigated blood eosinophil stability over 1 year using the Global Initiative for Chronic Obstructive Lung
Externí odkaz:
https://doaj.org/article/b5e9c1d4054b478582f71907727e45ed
Autor:
Gang Wang, Jenny Hallberg, Dimitrios Charalampopoulos, Maribel Casas Sanahuja, Robab Breyer-Kohansal, Arnulf Langhammer, Raquel Granell, Judith M. Vonk, Annemiek Mian, Núria Olvera, Lisbeth Mølgaard Laustsen, Eva Rönmark, Alicia Abellan, Alvar Agusti, Syed Hasan Arshad, Anna Bergström, H. Marike Boezen, Marie-Kathrin Breyer, Otto Burghuber, Anneli Clea Bolund, Adnan Custovic, Graham Devereux, Gavin C. Donaldson, Liesbeth Duijts, Ana Esplugues, Rosa Faner, Ferran Ballester, Judith Garcia-Aymerich, Ulrike Gehring, Sadia Haider, Sylvia Hartl, Helena Backman, John W. Holloway, Gerard H. Koppelman, Aitana Lertxundi, Turid Lingaas Holmen, Lesley Lowe, Sara M. Mensink-Bout, Clare S. Murray, Graham Roberts, Linnea Hedman, Vivi Schlünssen, Torben Sigsgaard, Angela Simpson, Jordi Sunyer, Maties Torrent, Stephen Turner, Maarten Van den Berge, Roel C.H. Vermeulen, Sigrid Anna Aalberg Vikjord, Jadwiga A. Wedzicha, Anke H. Maitland van der Zee, Erik Melén
Publikováno v:
ERJ Open Research, Vol 7, Iss 4 (2021)
Background The prevalences of obstructive and restrictive spirometric phenotypes, and their relation to early-life risk factors from childhood to young adulthood remain poorly understood. The aim was to explore these phenotypes and associations with
Externí odkaz:
https://doaj.org/article/308270070678456684381c04b9a9f6b6
Autor:
Gavin C. Donaldson, Andrew I. Ritchie, Peter M.A. Calverley, Jorgen Vestbo, Malin Fageras, Alberto de la Hoz, Enrica Bucchioni, Chris H. Compton, Karen Mezzi, Jadwiga A. Wedzicha
Publikováno v:
ERJ Open Research, Vol 7, Iss 4 (2021)
Externí odkaz:
https://doaj.org/article/e099bb87e6224320b988d321ff9f6de4