Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jado JC"'
Autor:
Elizabeth A. Winzeler, Krypton Carolino, Hannah Carter, Jado Jc, Trey Ideker, Gregory J. Fonseca, Michelle Dow
BackgroundIn vitro evolution and whole genome analysis has proven to be a powerful method for studying the mechanism of action of small molecules in many haploid microbes but has generally not been applied to human cell lines in part because their di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ddd7780850facaba5ab65647651431ad
https://doi.org/10.1101/2020.03.17.982181
https://doi.org/10.1101/2020.03.17.982181
Autor:
Luth MR; Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA., Godinez-Macias KP; Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA., Chen D; Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA., Okombo J; Center for Malaria Therapeutics and Antimicrobial Resistance, Columbia University Irving Medical Center, New York, NY, USA., Thathy V; Department of Microbiology and Immunology, Columbia University Irving Medical Center, New York, NY, USA.; Center for Malaria Therapeutics and Antimicrobial Resistance, Columbia University Irving Medical Center, New York, NY, USA., Cheng X; Global Health Drug Discovery Institute, Beijing, China., Daggupati S; Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA., Davies H; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Dhingra SK; Department of Microbiology and Immunology, Columbia University Irving Medical Center, New York, NY, USA.; Center for Malaria Therapeutics and Antimicrobial Resistance, Columbia University Irving Medical Center, New York, NY, USA., Economy JM; Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA., Edgar RCS; Biological Chemistry and Drug Discovery, Wellcome Centre for Anti-Infectives Research, University of Dundee, Dundee, UK., Gomez-Lorenzo MG; Global Health Medicines R&D, GSK, Tres Cantos, Madrid, Spain., Istvan ES; Department of Internal Medicine, Division of Infectious Diseases, Washington University School of Medicine, St. Louis, MO, USA.; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO, USA., Jado JC; Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA., LaMonte GM; Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA., Melillo B; Chemical Biology and Therapeutics Science Program, Broad Institute, Cambridge, MA, USA., Mok S; Center for Malaria Therapeutics and Antimicrobial Resistance, Columbia University Irving Medical Center, New York, NY, USA.; Division of Infectious Diseases, Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA., Narwal SK; Department of Microbiology and Immunology, Columbia University Irving Medical Center, New York, NY, USA.; Center for Malaria Therapeutics and Antimicrobial Resistance, Columbia University Irving Medical Center, New York, NY, USA., Ndiaye T; Department of Microbiology and Immunology, Columbia University Irving Medical Center, New York, NY, USA.; Center for Malaria Therapeutics and Antimicrobial Resistance, Columbia University Irving Medical Center, New York, NY, USA., Ottilie S; Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA., Palomo Diaz S; Global Health Medicines R&D, GSK, Tres Cantos, Madrid, Spain., Park H; Division of Infectious Diseases, Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA., Peña S; Química Farmacéutica, Departamento de Química Orgánica, Facultad de Química, Universidad de la República, Montevideo, Montevideo, Uruguay., Rocamora F; Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA., Sakata-Kato T; Global Health Drug Discovery Institute, Beijing, China.; Department of Protozoology, Nekken Institute for Tropical Medicine, Nagasaki University, Nagasaki, Japan., Small-Saunders JL; Center for Malaria Therapeutics and Antimicrobial Resistance, Columbia University Irving Medical Center, New York, NY, USA.; Division of Infectious Diseases, Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA., Summers RL; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA, USA.; Infectious Disease and Microbiome Program, The Broad Institute, Cambridge, MA, USA., Tumwebaze PK; Infectious Diseases Research Collaboration, Kampala, Uganda., Vanaerschot M; Department of Microbiology and Immunology, Columbia University Irving Medical Center, New York, NY, USA., Xia G; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA., Yeo T; Department of Microbiology and Immunology, Columbia University Irving Medical Center, New York, NY, USA.; Center for Malaria Therapeutics and Antimicrobial Resistance, Columbia University Irving Medical Center, New York, NY, USA., You A; Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA., Gamo FJ; Global Health Medicines R&D, GSK, Tres Cantos, Madrid, Spain., Goldberg DE; Department of Internal Medicine, Division of Infectious Diseases, Washington University School of Medicine, St. Louis, MO, USA.; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO, USA., Lee MCS; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.; Biological Chemistry and Drug Discovery, Wellcome Centre for Anti-Infectives Research, University of Dundee, Dundee, UK., McNamara CW; Calibr, a division of The Scripps Research Institute, La Jolla, CA, USA., Ndiaye D; Centre International de Recherche et de Formation en Génomique Appliquée et de Surveillance Sanitaire (CIGASS), Dakar, Senegal., Rosenthal PJ; Department of Medicine, University of California, San Francisco, San Francisco, CA, USA., Schreiber SL; Broad Institute of Harvard and MIT, Cambridge, MA, USA., Serra G; Química Farmacéutica, Departamento de Química Orgánica, Facultad de Química, Universidad de la República, Montevideo, Montevideo, Uruguay., De Siqueira-Neto JL; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, CA, USA., Skinner-Adams TS; Institute for Biomedicine and Glycomics and School of Environment and Science, Griffith University, Nathan, QLD, Australia., Uhlemann AC; Division of Infectious Diseases, Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA., Kato N; Global Health Drug Discovery Institute, Beijing, China.; Department of Protozoology, Nekken Institute for Tropical Medicine, Nagasaki University, Nagasaki, Japan., Lukens AK; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA, USA.; Infectious Disease and Microbiome Program, The Broad Institute, Cambridge, MA, USA., Wirth DF; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA, USA.; Infectious Disease and Microbiome Program, The Broad Institute, Cambridge, MA, USA., Fidock DA; Department of Microbiology and Immunology, Columbia University Irving Medical Center, New York, NY, USA.; Center for Malaria Therapeutics and Antimicrobial Resistance, Columbia University Irving Medical Center, New York, NY, USA.; Division of Infectious Diseases, Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA., Winzeler EA; Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA.; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, CA, USA.
Publikováno v:
Science (New York, N.Y.) [Science] 2024 Nov 29; Vol. 386 (6725), pp. eadk9893. Date of Electronic Publication: 2024 Nov 29.
Autor:
Jado JC; Division of Host-Microbe Systems & Therapeutics, Department of Pediatrics, University of California, San Diego, Gilman Dr., La Jolla, CA, 92093, USA.; Department of Medicine, Division of Medical Genetics, University of California San Diego, La Jolla, CA, 92093, USA., Dow M; Department of Medicine, Division of Medical Genetics, University of California San Diego, La Jolla, CA, 92093, USA.; Bioinformatics and Systems Biology Graduate Program, University of California San Diego, La Jolla, CA, 92093, USA.; Health Science, Department of Biomedical Informatics, School of Medicine, University of California San Diego, La Jolla, CA, 92093, USA., Carolino K; Division of Biological Sciences, University of California San Diego, La Jolla, CA, 92093, USA., Klie A; Department of Medicine, Division of Medical Genetics, University of California San Diego, La Jolla, CA, 92093, USA.; Bioinformatics and Systems Biology Graduate Program, University of California San Diego, La Jolla, CA, 92093, USA., Fonseca GJ; Department of Medicine, Meakins-Christie Laboratories, McGill University Health Centre, 1001 Decaire Blvd, Montreal, QC, H4A 3J1, Canada., Ideker T; Department of Medicine, Division of Medical Genetics, University of California San Diego, La Jolla, CA, 92093, USA. tideker@ucsd.edu.; Moores Cancer Center, University of California San Diego, La Jolla, CA, 92093, USA. tideker@ucsd.edu., Carter H; Department of Medicine, Division of Medical Genetics, University of California San Diego, La Jolla, CA, 92093, USA. hcarter@ucsd.edu.; Moores Cancer Center, University of California San Diego, La Jolla, CA, 92093, USA. hcarter@ucsd.edu., Winzeler EA; Division of Host-Microbe Systems & Therapeutics, Department of Pediatrics, University of California, San Diego, Gilman Dr., La Jolla, CA, 92093, USA. ewinzeler@ucsd.edu.; Department of Medicine, Division of Medical Genetics, University of California San Diego, La Jolla, CA, 92093, USA. ewinzeler@ucsd.edu.
Publikováno v:
Scientific reports [Sci Rep] 2024 Jun 18; Vol. 14 (1), pp. 13989. Date of Electronic Publication: 2024 Jun 18.
Autor:
Jado JC; Renal Physiopathology Laboratory, Department of Nephrology, Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM), Hospital General Universitario Gregorio Marañón, 28007 Madrid, Spain., Humanes B; Renal Physiopathology Laboratory, Department of Nephrology, Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM), Hospital General Universitario Gregorio Marañón, 28007 Madrid, Spain., González-Nicolás MÁ; Renal Physiopathology Laboratory, Department of Nephrology, Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM), Hospital General Universitario Gregorio Marañón, 28007 Madrid, Spain.; Department of Medicine, School of Medicine, Universidad Complutense, 28040 Madrid, Spain., Camaño S; Renal Physiopathology Laboratory, Department of Nephrology, Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM), Hospital General Universitario Gregorio Marañón, 28007 Madrid, Spain., Lara JM; Department of Pathology, Hospital General Universitario Gregorio Marañón, 28007 Madrid, Spain., López B; Department of Pathology, Hospital General Universitario Gregorio Marañón, 28007 Madrid, Spain., Cercenado E; Department of Microbiology, Hospital General Universitario Gregorio Marañón, 28007 Madrid, Spain., García-Bordas J; Department of Pathology, Hospital General Universitario Gregorio Marañón, 28007 Madrid, Spain., Tejedor A; Renal Physiopathology Laboratory, Department of Nephrology, Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM), Hospital General Universitario Gregorio Marañón, 28007 Madrid, Spain.; Department of Medicine, School of Medicine, Universidad Complutense, 28040 Madrid, Spain., Lázaro A; Renal Physiopathology Laboratory, Department of Nephrology, Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM), Hospital General Universitario Gregorio Marañón, 28007 Madrid, Spain.; Department of Physiology, School of Medicine, Universidad Complutense, 28040 Madrid, Spain.
Publikováno v:
Antioxidants (Basel, Switzerland) [Antioxidants (Basel)] 2020 Sep 03; Vol. 9 (9). Date of Electronic Publication: 2020 Sep 03.
Autor:
Antonova-Koch Y; School of Medicine, University of California, San Diego, 9500 Gilman Drive 0760, La Jolla, CA 92093, USA., Meister S; School of Medicine, University of California, San Diego, 9500 Gilman Drive 0760, La Jolla, CA 92093, USA., Abraham M; School of Medicine, University of California, San Diego, 9500 Gilman Drive 0760, La Jolla, CA 92093, USA., Luth MR; School of Medicine, University of California, San Diego, 9500 Gilman Drive 0760, La Jolla, CA 92093, USA., Ottilie S; School of Medicine, University of California, San Diego, 9500 Gilman Drive 0760, La Jolla, CA 92093, USA., Lukens AK; Harvard T. H. Chan School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA.; The Broad Institute, 415 Main Street, Cambridge, MA 02142, USA., Sakata-Kato T; The Broad Institute, 415 Main Street, Cambridge, MA 02142, USA., Vanaerschot M; Division of Infectious Diseases, Department of Microbiology and Immunology, Columbia University Medical Center, New York, NY 10032, USA., Owen E; Department of Biochemistry and Molecular Biology and Center for Malaria Research, Pennsylvania State University, University Park, PA 16802, USA., Jado JC; School of Medicine, University of California, San Diego, 9500 Gilman Drive 0760, La Jolla, CA 92093, USA., Maher SP; Center for Tropical and Emerging Global Diseases, University of Georgia, 500 D. W. Brooks Drive, Athens, GA 30602, USA.; Department of Global Health, University of South Florida, 3720 Spectrum Boulevard, Tampa, FL 33612, USA., Calla J; School of Medicine, University of California, San Diego, 9500 Gilman Drive 0760, La Jolla, CA 92093, USA., Plouffe D; The Genomics Institute of the Novartis Research Foundation, 10675 John J Hopkins Drive, San Diego, CA 92121, USA., Zhong Y; The Genomics Institute of the Novartis Research Foundation, 10675 John J Hopkins Drive, San Diego, CA 92121, USA., Chen K; The Genomics Institute of the Novartis Research Foundation, 10675 John J Hopkins Drive, San Diego, CA 92121, USA., Chaumeau V; Shoklo Malaria Research Unit, Mahidol Oxford Research Unit, Faculty of Tropical Medicine, Mahidol University, Mae Sot, Thailand.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Conway AJ; Center for Tropical and Emerging Global Diseases, University of Georgia, 500 D. W. Brooks Drive, Athens, GA 30602, USA.; Department of Global Health, University of South Florida, 3720 Spectrum Boulevard, Tampa, FL 33612, USA., McNamara CW; The Genomics Institute of the Novartis Research Foundation, 10675 John J Hopkins Drive, San Diego, CA 92121, USA., Ibanez M; The Genomics Institute of the Novartis Research Foundation, 10675 John J Hopkins Drive, San Diego, CA 92121, USA., Gagaring K; The Genomics Institute of the Novartis Research Foundation, 10675 John J Hopkins Drive, San Diego, CA 92121, USA., Serrano FN; Tres Cantos Medicines Development Campus, Malaria DPU, GlaxoSmithKline, Severo Ochoa 2, Tres Cantos 28760, Madrid, Spain., Eribez K; School of Medicine, University of California, San Diego, 9500 Gilman Drive 0760, La Jolla, CA 92093, USA., Taggard CM; School of Medicine, University of California, San Diego, 9500 Gilman Drive 0760, La Jolla, CA 92093, USA., Cheung AL; School of Medicine, University of California, San Diego, 9500 Gilman Drive 0760, La Jolla, CA 92093, USA., Lincoln C; School of Medicine, University of California, San Diego, 9500 Gilman Drive 0760, La Jolla, CA 92093, USA., Ambachew B; School of Medicine, University of California, San Diego, 9500 Gilman Drive 0760, La Jolla, CA 92093, USA., Rouillier M; Medicines for Malaria Venture, Post Office Box 1826, 20 Route de Pre-Bois, 1215 Geneva 15, Switzerland., Siegel D; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, 9500 Gilman Drive 0741, La Jolla, CA 92093, USA., Nosten F; Shoklo Malaria Research Unit, Mahidol Oxford Research Unit, Faculty of Tropical Medicine, Mahidol University, Mae Sot, Thailand.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Kyle DE; Center for Tropical and Emerging Global Diseases, University of Georgia, 500 D. W. Brooks Drive, Athens, GA 30602, USA.; Department of Global Health, University of South Florida, 3720 Spectrum Boulevard, Tampa, FL 33612, USA., Gamo FJ; Medicines for Malaria Venture, Post Office Box 1826, 20 Route de Pre-Bois, 1215 Geneva 15, Switzerland., Zhou Y; The Genomics Institute of the Novartis Research Foundation, 10675 John J Hopkins Drive, San Diego, CA 92121, USA., Llinás M; Department of Biochemistry and Molecular Biology and Center for Malaria Research, Pennsylvania State University, University Park, PA 16802, USA.; Department of Chemistry and Center for Infectious Diseases Dynamics, Pennsylvania State University, University Park, PA 16802, USA., Fidock DA; Division of Infectious Diseases, Department of Microbiology and Immunology, Columbia University Medical Center, New York, NY 10032, USA., Wirth DF; Harvard T. H. Chan School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA.; The Broad Institute, 415 Main Street, Cambridge, MA 02142, USA., Burrows J; Medicines for Malaria Venture, Post Office Box 1826, 20 Route de Pre-Bois, 1215 Geneva 15, Switzerland., Campo B; Medicines for Malaria Venture, Post Office Box 1826, 20 Route de Pre-Bois, 1215 Geneva 15, Switzerland., Winzeler EA; School of Medicine, University of California, San Diego, 9500 Gilman Drive 0760, La Jolla, CA 92093, USA. ewinzeler@ucsd.edu.; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, 9500 Gilman Drive 0741, La Jolla, CA 92093, USA.
Publikováno v:
Science (New York, N.Y.) [Science] 2018 Dec 07; Vol. 362 (6419).
Autor:
Lázaro A; Renal Physiopathology Laboratory, Department of Nephrology, Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM), Hospital General Universitario Gregorio Marañón, 28007 Madrid, Spain., Humanes B; Renal Physiopathology Laboratory, Department of Nephrology, Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM), Hospital General Universitario Gregorio Marañón, 28007 Madrid, Spain., Jado JC; Renal Physiopathology Laboratory, Department of Nephrology, Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM), Hospital General Universitario Gregorio Marañón, 28007 Madrid, Spain., Mojena M; Renal Physiopathology Laboratory, Department of Nephrology, Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM), Hospital General Universitario Gregorio Marañón, 28007 Madrid, Spain., González-Nicolás MÁ; Renal Physiopathology Laboratory, Department of Nephrology, Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM), Hospital General Universitario Gregorio Marañón, 28007 Madrid, Spain., Del Cañizo JF; Medicine and Surgery Unit, IiSGM, Hospital General Universitario Gregorio Marañón, 28007 Madrid, Spain; Department of Surgery, Faculty of Medicine, Complutense University of Madrid, 28040 Madrid, Spain., Tejedor A; Renal Physiopathology Laboratory, Department of Nephrology, Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM), Hospital General Universitario Gregorio Marañón, 28007 Madrid, Spain; Department of Medicine, Faculty of Medicine, Complutense University of Madrid, 28040 Madrid, Spain., Lledó-García E; Urology Department, IiSGM, Hospital General Universitario Gregorio Marañón, 28007 Madrid, Spain.
Publikováno v:
BioMed research international [Biomed Res Int] 2016; Vol. 2016, pp. 2518626. Date of Electronic Publication: 2016 Jul 31.
Autor:
Humanes B; Renal Physiopathology Laboratory, Department of Nephrology, Gregorio Marañón University Hospital, IiSGM, 28007 Madrid, Spain., Jado JC; Renal Physiopathology Laboratory, Department of Nephrology, Gregorio Marañón University Hospital, IiSGM, 28007 Madrid, Spain., Camaño S; Renal Physiopathology Laboratory, Department of Nephrology, Gregorio Marañón University Hospital, IiSGM, 28007 Madrid, Spain., López-Parra V; Renal Physiopathology Laboratory, Department of Nephrology, Gregorio Marañón University Hospital, IiSGM, 28007 Madrid, Spain., Torres AM; Renal Physiopathology Laboratory, Department of Nephrology, Gregorio Marañón University Hospital, IiSGM, 28007 Madrid, Spain., Álvarez-Sala LA; Department of Medicine, School of Medicine, Complutense University of Madrid, 28040 Madrid, Spain ; Department of Internal Medicine, Gregorio Marañón University Hospital, IiSGM, 28007 Madrid, Spain., Cercenado E; Department of Medicine, School of Medicine, Complutense University of Madrid, 28040 Madrid, Spain ; Clinical Microbiology and Infectious Diseases Department, Gregorio Marañón University Hospital, IiSGM, 28007 Madrid, Spain., Tejedor A; Renal Physiopathology Laboratory, Department of Nephrology, Gregorio Marañón University Hospital, IiSGM, 28007 Madrid, Spain ; Department of Medicine, School of Medicine, Complutense University of Madrid, 28040 Madrid, Spain., Lázaro A; Renal Physiopathology Laboratory, Department of Nephrology, Gregorio Marañón University Hospital, IiSGM, 28007 Madrid, Spain.
Publikováno v:
BioMed research international [Biomed Res Int] 2015; Vol. 2015, pp. 704382. Date of Electronic Publication: 2015 Oct 04.
Publikováno v:
Kidney international [Kidney Int] 2013 Jun; Vol. 83 (6), pp. 1201-2.