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pro vyhledávání: '"Jaden T Cowan"'
Autor:
Mark T. Heise, Thomas E. Morrison, Subramaniam Ananthan, Joseph A. Maddry, Sanjay Sarkar, Jessica L. Smith, Kevin J Rodzinak, Nicole N. Haese, Daniel N. Streblow, Nathaniel J. Moorman, Cassilyn E. Streblow, Ashish K. Pathak, Vibha Pathak, Aaron D Streblow, Lynn Rasmussen, Fahim Ahmad, Corinne E. Augelli-Szafran, S Kaleem Ahmed, Victor R. DeFilippis, Robert Bostwick, Craig N. Kreklywich, Mark J. Suto, Sixue Zhang, Robbie Allen, Alec J. Hirsch, Jaden T Cowan, Babu L. Tekwani, Kiley Bonin, Nichole A. Tower, Wes Sander, Valerie J Smith, Mousheng Wu, John M Gerdes, Clayton R. Morrison, Omar Moukha-Chafiq
Publikováno v:
J Med Chem
A benzo[6]annulene, 4-(tert-butyl)-N-(3-methoxy-5,6,7,8-tetrahydronaphthalen-2-yl) benzamide (1a), was identified as an inhibitor against Chikungunya virus (CHIKV) with antiviral activity EC(90) = 1.45 μM and viral titer reduction (VTR) of 2.5 log a