Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jade R, Hopkins"'
Autor:
Mathieu Ferrari, Matteo Righi, Vania Baldan, Patrycja Wawrzyniecka, Anna Bulek, Alexander Kinna, Biao Ma, Reyisa Bughda, Zulaikha Akbar, Saket Srivastava, Isaac Gannon, Mathew Robson, James Sillibourne, Ram Jha, Mohamed El-Kholy, Oliver Muhammad Amin, Evangelia Kokalaki, Mohammed Amin Banani, Rehan Hussain, William Day, Wen Chean Lim, Priyanka Ghongane, Jade R. Hopkins, Dennis Jungherz, Marco Herling, Martin Welin, Sachin Surade, Michael Dyson, John McCafferty, Derek Logan, Shaun Cordoba, Simon Thomas, Andrew Sewell, Paul Maciocia, Shimobi Onuoha, Martin Pule
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Peripheral T cell lymphomas are typically aggressive with a poor prognosis. Unlike other hematologic malignancies, the lack of target antigens to discriminate healthy from malignant cells limits the efficacy of immunotherapeutic approaches.
Externí odkaz:
https://doaj.org/article/0a0cba1c19b24f4e8e75069f7a2b0924
Autor:
Thomas Whalley, Garry Dolton, Paul E. Brown, Aaron Wall, Linda Wooldridge, Hugo van den Berg, Anna Fuller, Jade R. Hopkins, Michael D. Crowther, Meriem Attaf, Robin R. Knight, David K. Cole, Mark Peakman, Andrew K. Sewell, Barbara Szomolay
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The strong links between (Human Leukocyte Antigen) HLA, infection and autoimmunity combine to implicate T-cells as primary triggers of autoimmune disease (AD). T-cell crossreactivity between microbially-derived peptides and self-peptides has been sho
Externí odkaz:
https://doaj.org/article/1a8fe277e505431893c2b64061e4a518
Autor:
Andrew K. Sewell, Christopher R. Pudney, David K. Cole, Dragana A. M. Catici, Jade R. Hopkins, Marc W. van der Kamp, Rory M. Crean, Vickery L. Arcus
Publikováno v:
The Febs Journal
Hopkins, J R, Crean, R M, Catici, D A M, Sewell, A K, Arcus, V L, Van Der Kamp, M W, Cole, D & Pudney, C R 2020, ' Peptide cargo tunes a network of correlated motions in human leukocyte antigens ', FEBS Journal . https://doi.org/10.1111/febs.15278
Hopkins, J R, Crean, R M, Catici, D A M, Sewell, A K, Arcus, V L, Van Der Kamp, M W, Cole, D & Pudney, C R 2020, ' Peptide cargo tunes a network of correlated motions in human leukocyte antigens ', FEBS Journal . https://doi.org/10.1111/febs.15278
Most biomolecular interactions are typically thought to increase the (local) rigidity of a complex, for example, in drug‐target binding. However, detailed analysis of specific biomolecular complexes can reveal a more subtle interplay between bindin
Publikováno v:
Discovery Immunology. 1
The intracellular proteome of virtually every nucleated cell in the body is continuously presented at the cell surface via the human leukocyte antigen class I (HLA-I) antigen processing pathway. This pathway classically involves proteasomal degradati
Autor:
Andrew James Godkin, Florian Madura, Andrew K. Sewell, David K. Cole, Jade R. Hopkins, Nathaniel Liddy, Anna Marta Bulek, Andrew Trimby, E. Joel Loveridge, Andrea J. A. Schauenburg, Pierre J. Rizkallah, Bent K. Jakobsen, Stephen A. Wells, Anna Fuller, John J. Miles, Mateusz Legut, Malkit Sami, Christopher J. Holland, Yi Li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05af3d7484dbdca54fcaedb0db319f63
https://doi.org/10.1002/eji.201948085/v2/response1
https://doi.org/10.1002/eji.201948085/v2/response1
Autor:
Florian, Madura, Pierre J, Rizkallah, Mateusz, Legut, Christopher J, Holland, Anna, Fuller, Anna, Bulek, Andrea J, Schauenburg, Andrew, Trimby, Jade R, Hopkins, Stephen A, Wells, Andrew, Godkin, John J, Miles, Malkit, Sami, Yi, Li, Nathaniel, Liddy, Bent K, Jakobsen, E Joel, Loveridge, David K, Cole, Andrew K, Sewell
Publikováno v:
European Journal of Immunology
The HLA‐A*02:01‐restricted decapeptide EAAGIGILTV, derived from melanoma antigen recognized by T‐cells‐1 (MART‐1) protein, represents one of the best‐studied tumor associated T‐cell epitopes, but clinical results targeting this peptide