Zobrazeno 1 - 10
of 188
pro vyhledávání: '"Jade K, Forwood"'
Autor:
Subir Sarker, Hayley K. Roberts, Naomie Tidd, Shayne Ault, Georgia Ladmore, Andrew Peters, Jade K. Forwood, Karla Helbig, Shane R. Raidal
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/ea0c9b5fb105469ba73ca4c2ff101ca1
Autor:
Seyed Mohammad Ghafoori, Ashish Sethi, Gayle F. Petersen, Mohammad Hossein Tanipour, Paul R. Gooley, Jade K. Forwood
Publikováno v:
Cells, Vol 13, Iss 14, p 1202 (2024)
SOX proteins are a family of transcription factors (TFs) that play critical functions in sex determination, neurogenesis, and chondrocyte differentiation, as well as cardiac, vascular, and lymphatic development. There are 20 SOX family members in hum
Externí odkaz:
https://doaj.org/article/c1a1ba8566ae474ca098ef2907183cd9
Autor:
Wen Juan Tu, Michelle Melino, Jenny Dunn, Robert D. McCuaig, Helle Bielefeldt-Ohmann, Sofiya Tsimbalyuk, Jade K. Forwood, Taniya Ahuja, John Vandermeide, Xiao Tan, Minh Tran, Quan Nguyen, Liang Zhang, Andy Nam, Liuliu Pan, Yan Liang, Corey Smith, Katie Lineburg, Tam H. Nguyen, Julian D. J. Sng, Zhen Wei Marcus Tong, Keng Yih Chew, Kirsty R. Short, Roger Le Grand, Nabila Seddiki, Sudha Rao
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Abstract In vitro, ACE2 translocates to the nucleus to induce SARS-CoV-2 replication. Here, using digital spatial profiling of lung tissues from SARS-CoV-2-infected golden Syrian hamsters, we show that a specific and selective peptide inhibitor of nu
Externí odkaz:
https://doaj.org/article/c807331d48fd44e7b2a60c1357a9b798
Autor:
Seyed Mohammad Ghafoori, Gayle F. Petersen, Deborah G. Conrady, Brandy M. Calhoun, Matthew Z. Z. Stigliano, Ruth O. Baydo, Rena Grice, Jan Abendroth, Donald D. Lorimer, Thomas E. Edwards, Jade K. Forwood
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Influenza virus (IV) causes several outbreaks of the flu each year resulting in an economic burden to the healthcare system in the billions of dollars. Several influenza pandemics have occurred during the last century and estimated to have c
Externí odkaz:
https://doaj.org/article/76d2ef5b49eb4543ad2cf4338202406a
Publikováno v:
Cells, Vol 13, Iss 1, p 71 (2023)
Cellular nucleocytoplasmic trafficking is mediated by the importin family of nuclear transport proteins. The well-characterized importin alpha (IMPA) and importin beta (IMPB) nuclear import pathway plays a crucial role in the innate immune response t
Externí odkaz:
https://doaj.org/article/bada7eaadea84e1d9e515e8a2a04b5f0
Publikováno v:
Viruses, Vol 16, Iss 1, p 33 (2023)
Australian bat lyssavirus (ABLV) shows similar clinical symptoms as rabies, but there are currently no protein structures available for ABLV proteins. In lyssaviruses, the interaction between nucleoprotein (N) and phosphoprotein (N) in the absence of
Externí odkaz:
https://doaj.org/article/d851787a4b774ba998007d7926d7995b
Publikováno v:
PLoS ONE, Vol 18, Iss 8, p e0289992 (2023)
Bacterial antibiotic resistance remains an ever-increasing worldwide problem, requiring new approaches and enzyme targets. Acinetobacter baumannii is recognised as one of the most significant antibiotic-resistant bacteria, capable of carrying up to 4
Externí odkaz:
https://doaj.org/article/dafaab5a99b74f11a3ee46d959dd8dc0
Autor:
Thilini S. Munasinghe, Megan R. Edwards, Sofiya Tsimbalyuk, Olivia A. Vogel, Kate M. Smith, Murray Stewart, Justin K. Foster, Loretta A. Bosence, David Aragão, Justin A. Roby, Christopher F. Basler, Jade K. Forwood
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
MERS-CoV ORF4b antagonizes host innate immune response, partially via blocking nuclear import adapter IMPα activity and preventing nuclear translocation of NF-κB. Here, Munasinghe and Edwards et al. biochemically and structurally define the interac
Externí odkaz:
https://doaj.org/article/24c49199db9a4db7bb2d31b55376fd00
Autor:
Babu Kanti Nath, Tridip Das, Andrew Peters, Suman Das Gupta, Subir Sarker, Jade K. Forwood, Shane R. Raidal, Shubhagata Das
Publikováno v:
Viruses, Vol 15, Iss 10, p 2025 (2023)
Pigeon circovirus (PiCV) is considered to be genetically diverse, with a relatively small circular single-stranded DNA genome of 2 kb that encodes for a capsid protein (Cap) and a replication initiator protein (Rep). Australasia is known to be the or
Externí odkaz:
https://doaj.org/article/5e56689901f3454face126ed85b0e040
Autor:
Sofiya Tsimbalyuk, Aleksander Shornikov, Parul Srivastava, Van Thi Bich Le, Imani Warren, Yogesh B. Khandokar, Misty L. Kuhn, Jade K. Forwood
Publikováno v:
Cells, Vol 12, Iss 14, p 1829 (2023)
Polyamines are simple yet critical molecules with diverse roles in numerous pathogenic and non-pathogenic organisms. Regulating polyamine concentrations affects the transcription and translation of genes and proteins important for cell growth, stress
Externí odkaz:
https://doaj.org/article/94572e486c244459aa8fd536b1bf03cc