Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Jade, Degrandmaison"'
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Due to their low expression levels, complex multi-pass transmembrane structure, and the current lack of highly specific antibodies, the assessment of endogenous G protein-coupled receptors (GPCRs) remains challenging. While most of the research regar
Externí odkaz:
https://doaj.org/article/b51269a28d5242bfa4a983b804d44a6b
Autor:
Christine Lavoie, Jade Degrandmaison, Véronique Blais, Jim Boulter, Jean-Luc Parent, Samuel Génier, Khaled Abdallah, Louis Gendron, Catherine M. Cahill, Francis Bergeron, Marie-Pier Lalumière
Publikováno v:
Proc Natl Acad Sci U S A
With over 30% of current medications targeting this family of proteins, G-protein–coupled receptors (GPCRs) remain invaluable therapeutic targets. However, due to their unique physicochemical properties, their low abundance, and the lack of highly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e552663e1b33fafd3197dc42e973a4a1
https://doi.org/10.1073/pnas.1917906117
https://doi.org/10.1073/pnas.1917906117
Publikováno v:
Frontiers in cellular neuroscience. 16
Due to their low expression levels, complex multi-pass transmembrane structure, and the current lack of highly specific antibodies, the assessment of endogenous G protein-coupled receptors (GPCRs) remains challenging. While most of the research regar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c38eabaa30d459207280e5e3b51e2f32
https://pubmed.ncbi.nlm.nih.gov/35173584
https://pubmed.ncbi.nlm.nih.gov/35173584
Publikováno v:
Journal of neuroscience researchREFERENCES. 100(1)
Over the past several years, studies have highlighted the δ-opioid receptor (DOPr) as a promising therapeutic target for chronic pain management. While exhibiting milder undesired effects than most currently prescribed opioids, its specific agonists
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a3a34c3304feb1168fe0080d51c097b
https://pubmed.ncbi.nlm.nih.gov/34559903
https://pubmed.ncbi.nlm.nih.gov/34559903
Autor:
Jade Degrandmaison, Samuel Picard, Louis Fréchette, Samuel Génier, Jean-Luc Parent, Chantal Binda, Steve Jean, Eric Marsault
Publikováno v:
J Biol Chem
Accumulating evidence indicates that G protein–coupled receptors (GPCRs) interact with Rab GTPases during their intracellular trafficking. How GPCRs recruit and activate the Rabs is unclear. Here, we report that depletion of endogenous L-type prost
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45ddf0adca4608ae8d0287405f29be38
https://doi.org/10.1074/jbc.ra119.008233
https://doi.org/10.1074/jbc.ra119.008233
Autor:
Jean-Luc Parent, Mannix Auger-Messier, Hugo Giguère, Julien Malette, Jade Degrandmaison, Guylain Boulay, Jonathan Berthiaume, Maude Frappier
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1866:1249-1259
Intact store-operated calcium entry (SOCE) mechanisms ensure the maintenance of Ca2+ homeostasis in cardiomyocytes while their dysregulation promotes the development of cardiomyopathies. To better understand this calcium handling process in cardiomyo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0b63fd366db60ea5930c0d30b6fa488
https://doi.org/10.1016/j.bbamcr.2019.03.017
https://doi.org/10.1016/j.bbamcr.2019.03.017
Autor:
Louis, Fréchette, Jade, Degrandmaison, Chantal, Binda, Marilou, Boisvert, Laurie, Côté, Thomas, Michaud, Marie-Pier, Lalumière, Louis, Gendron, Jean-Luc, Parent
Publikováno v:
Biochimica et biophysica acta. General subjects. 1865(11)
Mechanisms governing localization, trafficking and signaling of G protein-coupled receptors (GPCRs) are critical in cell function. Protein-protein interactions are determinant in these processes. However, there are very little interacting proteins kn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4b2609c5acd2018a4dfef9083af72c61
https://pubmed.ncbi.nlm.nih.gov/34352343
https://pubmed.ncbi.nlm.nih.gov/34352343
Autor:
Louis, Fréchette, Chantal, Binda, Samuel, Génier, Jade, Degrandmaison, Marilou, Boisvert, Jean-Luc, Parent
Publikováno v:
Cellular signalling. 72
Mechanisms controlling the recycling of G protein-coupled receptors (GPCRs) remain largely unclear. We report that GGA3 (Golgi-associated, γ adaptin ear containing, ADP-ribosylation factor-binding protein 3) regulates the recycling and signaling of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bbfce2ad6cffd94831cc4bd80b89fb62
https://pubmed.ncbi.nlm.nih.gov/32334026
https://pubmed.ncbi.nlm.nih.gov/32334026
Autor:
Jean-Luc Parent, Jade Degrandmaison, Chantal Binda, Laurie Côté, Louis Gendron, Thomas Michaud, Louis Fréchette, Marilou Boisvert, Marie-Pier Lalumière
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1865:129969
Background Mechanisms governing localization, trafficking and signaling of G protein-coupled receptors (GPCRs) are critical in cell function. Protein-protein interactions are determinant in these processes. However, there are very little interacting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6a6d6d7972db3327f20cbfa033b2833
https://doi.org/10.1016/j.bbagen.2021.129969
https://doi.org/10.1016/j.bbagen.2021.129969