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Autor:
Jacquline A. Brassard, Timothy J. Maziasz, Carl L. Alden, Benjamin E. Trump, Catherine M. Venturini, Roderick T. Bunch, Kanwar Nasir M. Khan, Alane T. Koki, Dale L. Morris
Publikováno v:
Toxicologic Pathology. 26:612-620
Cyclooxygenase (COX) exists in 2 related but unique isoforms: one is constitutive (COX-1) and functions in normal cell physiology, and the other is inducible (COX-2) and is expressed in response to inflammatory stimuli. Nonsteroidal antiinflammatory