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pro vyhledávání: '"Jacquine C. Niles"'
Autor:
Feng Gu, Sang Soo Hah, James C. Delaney, Steven R. Tannenbaum, John M. Essigmann, Jacquine C. Niles, Paul T. Henderson, William L. Neeley
Publikováno v:
Chemical Research in Toxicology. 18:12-18
The DNA oxidation product 7,8-dihydro-8-oxoguanine (8-oxoG) forms several mutagenic oxidation products, including a metastable oxaluric acid (Oa) derivative. We report here that a synthetic oligonucleotide containing Oa hydrolyzes under simulated "in