Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Jacquie, Schein"'
Autor:
Simon Haile, Richard D. Corbett, Tina MacLeod, Steve Bilobram, Duane Smailus, Philip Tsao, Heather Kirk, Helen McDonald, Pawan Pandoh, Miruna Bala, Martin Hirst, Diane Miller, Richard A. Moore, Andrew J. Mungall, Jacquie Schein, Robin J. Coope, Yussanne Ma, Yongjun Zhao, Rob A. Holt, Steven J. Jones, Marco A. Marra
Publikováno v:
BMC Genomics, Vol 18, Iss 1, Pp 1-14 (2017)
Abstract Background RNA-Sequencing (RNA-seq) is now commonly used to reveal quantitative spatiotemporal snapshots of the transcriptome, the structures of transcripts (splice variants and fusions) and landscapes of expressed mutations. However, standa
Externí odkaz:
https://doaj.org/article/0567feec5d9240578c381c3fcd372ebe
Autor:
Yaoqing Shen, Stephen Yip, Marco A. Marra, Yongjun Zhao, Richard A. Moore, Howard John Lim, Tony Ng, Erin Pleasance, Yussanne Ma, Andrew J. Mungall, Kasmintan A. Schrader, D.J. Renouf, Brandon S. Sheffield, Steven J.M. Jones, Martin Jones, Janessa Laskin, Nazir Ahmad Dar, Carolyn Ch'ng, Jacquie Schein
Publikováno v:
Annals of Oncology
Personalised oncogenomics analysis revealed potential oncogene addiction of the AP-1 transcriptional complex in a chemo-refractory and MMR-deficient tumor from a patient with metastatic colon cancer. Based on this, treatment with the angiotensin rece
Autor:
Upal Basu-Roy, Andy Chu, Andrew J. Mungall, Yunfei Wen, Jacquie Schein, Denise Brooks, Alka Mansukhani, Jinsong Liu, Cristian Coarfa, Sagar L. Patil, Amy C. Rowat, Nina Thiessen, Xinna Zhang, Anil K. Sood, Preethi H. Gunaratne, Marco A. Marra, Anadulce Hernandez-Herrera, Reanne Bowlby, Emilia L. Lim, Lykke Pedersen, Chad V. Pecot, Yinghong Pan, Steven J.M. Jones, Clara K. Chan, Yussanne Ma, Payal Sipahimalani, Gordon Robertson, Richard A. Moore
Publikováno v:
Oncotarget
Pan, Y, Robertson, G, Pedersen, L, Lim, E, Hernandez-Herrera, A, Rowat, A C, Patil, S L, Chan, C K, Wen, Y, Zhang, X, Basu-Roy, U, Mansukhani, A, Chu, A, Sipahimalani, P, Bowlby, R, Brooks, D, Thiessen, N, Coarfa, C, Ma, Y, Moore, R A, Schein, J E, Mungall, A J, Liu, J, Pecot, C V, Sood, A K, Jones, S J M, Marra, M A & Gunaratne, P H 2016, ' miR-509-3p is clinically significant and strongly attenuates cellular migration and multi-cellular spheroids in ovarian cancer ', OncoTarget, vol. 7, no. 18, pp. 25930-25948 . https://doi.org/10.18632/oncotarget.8412
Oncotarget, vol 7, iss 18
Pan, Y, Robertson, G, Pedersen, L, Lim, E, Hernandez-Herrera, A, Rowat, A C, Patil, S L, Chan, C K, Wen, Y, Zhang, X, Basu-Roy, U, Mansukhani, A, Chu, A, Sipahimalani, P, Bowlby, R, Brooks, D, Thiessen, N, Coarfa, C, Ma, Y, Moore, R A, Schein, J E, Mungall, A J, Liu, J, Pecot, C V, Sood, A K, Jones, S J M, Marra, M A & Gunaratne, P H 2016, ' miR-509-3p is clinically significant and strongly attenuates cellular migration and multi-cellular spheroids in ovarian cancer ', OncoTarget, vol. 7, no. 18, pp. 25930-25948 . https://doi.org/10.18632/oncotarget.8412
Oncotarget, vol 7, iss 18
Ovarian cancer presents as an aggressive, advanced stage cancer with widespread metastases that depend primarily on multicellular spheroids in the peritoneal fluid. To identify new druggable pathways related to metastatic progression and spheroid for
Autor:
Nathalie A. Johnson, Susana Ben-Neriah, Sohrab P. Shah, Jacquie Schein, Douglas E. Horsman, Adele Telenius, Andrew J. Mungall, Merrill Boyle, Tang Lee, Betty Lai, Randy D. Gascoyne, Joseph M. Connors, Marco A. Marra, Allen Delaney, K-John Cheung, Dorothy Cheung
Publikováno v:
Genes, Chromosomes and Cancer. 49:669-681
A multiplatform approach, including conventional cytogenetic techniques, BAC array comparative genomic hybridization, and Affymetrix 500K SNP arrays, was applied to the study of the tumor genomes of 25 follicular lymphoma biopsy samples with paired n
Autor:
Hong Qian, Ryan D. Morin, Inanc Birol, Tesa M. Severson, Richard Varhol, Bruce Woolcock, Yongjun Zhao, Richard Corbett, Florian Kuchenbauer, Charlot Jf, Rodrigo Goya, Tcherpakov M, Joseph M. Connors, Marco A. Marra, Douglas E. Horsman, Randy D. Gascoyne, Nathalie A. Johnson, Robert A. Holt, Richard A. Moore, Andrew J. Mungall, Allen Delaney, Samuel Aparicio, Angela K Y Tam, Hao Zhu, Michelle Moksa, Jacquie Schein, Shashkin P, Martin Hirst, Damian Yap, Jianghong An, Steven J.M. Jones, Kimbara M, Humphries Rk, Paul Je, Merrill Boyle, Obi L. Griffith, Sohrab P. Shah, Duane E Smailus
Publikováno v:
Nature genetics
Follicular lymphoma (FL) and the GCB subtype of diffuse large B-cell lymphoma (DLBCL) derive from germinal center B cells. Targeted resequencing studies have revealed mutations in various genes encoding proteins in the NF-kappaB pathway that contribu
Autor:
Kathy Seeger, G. Bothe, Rob Squares, Lee Murphy, Valentina Tosato, Michael A. Quail, Angela Lord, Alasdair Ivens, Christopher S. Peacock, Simon Rutter, Joel Rinta, Audrey Fraser, Dhileep Sivam, Carlo V. Bruschi, Nigel Fosker, Arlette Goble, Jenefer M. Blackwell, Silke Müller-Auer, K. Borzym, Robert L. Davies, Heather Munden, Holger Wedler, André Goffeau, Ellen Adlem, Christy Vogt, Susan O'Neil, David C. Schwartz, Siri Nelson, Bénédicte Purnelle, Angela K. Cruz, Martin Pentony, Deborah F. Smith, Michael A. Rieger, Laura Ciarloni, Kenneth Stuart, Marco A. Marra, Sven Klages, David L. Saunders, Alfred Beck, Marie-Adèle Rajandream, David Masuy, Andrew J Knights, Atashi Anupama, Karen Oliver, Helmut Hilbert, Rolf Wambutt, David Harris, Gabriella Bianchettin, Sarah Sharp, Nathalie Bason, Alberto C.C. Frasch, Matt Collins, Heesun Shin, Jeronimo C. Ruiz, Jeremy C. Mottram, David Horn, Richard M.R. Coulson, Elizabeth A. Worthey, Amber Seyler, Christopher Bauser, Natasha Larke, Bart Barrell, Ester Rabbinowitsch, John Woodward, Zina Apostolou, Christine Clayton, Christiane Hertz-Fowler, Ellen Sisk, Steve Squares, Gholam Fazelina, Laura Robertson, Johan Robben, T. Warren, Halina Norbertczak, Javier G. De Gaudenzi, Monika Fuchs, Shulamit Michaeli, Matthew Berriman, Claudia Gabel, Melanie Schäfer, Peter J. Myler, Thomas M. Pohl, Tin Louie, Rita Aert, Claire Price, Stephen M. Beverley, Guido Volckaert, Deborah E. Dobson, Richard Reinhardt, Lyudmila Litvin, Andreas Duesterhoeft, Ann Cronin, Jacquie Schein, Shiguo Zhou, Wolfgang Zimmermann, Gautam Aggarwal, Eithon Cadag, Yiting Huang, Michael Kube, Philip Attipoe, Keith R. Matthews
Publikováno v:
Ivens, A C, Peacock, C S, Worthey, E A, Murphy, L, Aggarwal, G, Berriman, M, Sisk, E, Rajandream, M-A, Adlem, E, Aert, R, Anupama, A, Apostolou, Z, Attipoe, P, Bason, N, Bauser, C, Beck, A, Beverley, S M, Bianchettin, G, Borzym, K, Bothe, G, Bruschi, C V, Collins, M, Cadag, E, Ciarloni, L, Clayton, C, Coulson, R M R, Cronin, A, Cruz, A K, Davies, R M, De Gaudenzi, J, Dobson, D E, Duesterhoeft, A, Fazelina, G, Fosker, N, Frasch, A C, Fraser, A, Fuchs, M, Gabel, C, Goble, A, Goffeau, A, Harris, D, Hertz-Fowler, C, Hilbert, H, Horn, D, Huang, Y, Klages, S, Knights, A, Kube, M, Larke, N, Litvin, L, Lord, A, Louie, T, Marra, M, Masuy, D, Matthews, K, Michaeli, S, Mottram, J C, Müller-Auer, S, Munden, H, Nelson, S, Norbertczak, H, Oliver, K, O'neil, S, Pentony, M, Pohl, T M, Price, C, Purnelle, B, Quail, M A, Rabbinowitsch, E, Reinhardt, R, Rieger, M, Rinta, J, Robben, J, Robertson, L, Ruiz, J C, Rutter, S, Saunders, D, Schäfer, M, Schein, J, Schwartz, D C, Seeger, K, Seyler, A, Sharp, S, Shin, H, Sivam, D, Squares, R, Squares, S, Tosato, V, Vogt, C, Volckaert, G, Wambutt, R, Warren, T, Wedler, H, Woodward, J, Zhou, S, Zimmermann, W, Smith, D F, Blackwell, J M, Stuart, K D, Barrell, B & Myler, P J 2005, ' The genome of the kinetoplastid parasite, Leishmania major ', Science, vol. 309, no. 5733, pp. 436-42 . https://doi.org/10.1126/science.1112680
Leishmaniaspecies cause a spectrum of human diseases in tropical and subtropical regions of the world. We have sequenced the 36 chromosomes of the 32.8-megabase haploid genome ofLeishmania major(Friedlin strain) and predict 911 RNA genes, 39 pseudoge
Autor:
Steven J.M. Jones, Anca Petrescu, Matt Myhre, Asim Siddiqui, Lindsay D. Eltis, Marco A. Marra, Yaron S.N. Butterfield, Jacquie Schein, Duane E. Smailus, Satoru Shimizu, Jeff M. Stott, Robert A. Holt, Eiji Masai, René L. Warren, Masao Fukuda, Julian Davies, Jaswinder Khattra, Manisha Dosanjh, Fiona S. L. Brinkman, Hisashi Kudo, Hiroyuki Kobayashi, Heesun Shin, William W. L. Hsiao, Keisuke Miyauchi, George S. Yang, William W. Mohn
Publikováno v:
Journal of Bacteriology. 186:7783-7795
Rhodococcus sp. strain RHA1, a potent polychlorinated-biphenyl (PCB)-degrading strain, contains three linear plasmids ranging in size from 330 to 1,100 kb. As part of a genome sequencing project, we report here the complete sequence and characterizat
Autor:
Jonathan H. Dennis, Michael Brudno, Anindya Dutta, Richard M. Myers, Ian Dunham, Eduardo Eyras, S. S. Marticke, Alexandre Reymond, Anason S. Halees, Greg Schuler, M. G. Rosenfeld, Mikhail Nefedov, Robert E. Kingston, Elizabeth Anton, Tyra G. Wolfsberg, Alice C. Young, Kris A. Wetterstrand, C. K. Glass, Nancy F. Hansen, Gayle K. Clelland, Diane I. Schroeder, Jean L. Chang, H. Shin, Zhou Zhu, Nigel P. Carter, William Stafford Noble, Jenny McDowell, Ugrappa Nagalakshmi, Heike Fiegler, Philipp Kapranov, Peggy J. Farnham, Joanna C. Fowler, S. C. Harvey, Michael O. Dorschner, D. R. Inman, George V. Popescu, Jan-Jaap Wesselink, P. Groth, Baoli Zhu, H. Hirsch, James C. Wallace, Elise A. Feingold, S. Jin, Gabriel Robins, Thomas R. Gingeras, F. Denoeud, W. Tongprasit, Robert Castelo, Ross C. Hardison, John A. Stamatoyannopoulos, Joel Rozowsky, Eric A. Stone, Zheng Lian, J. E. Norton, Y. S. Kwon, Viktor Stolc, Michael C. Pirrung, Min-Feng Yu, A. Yang, W. J. Kent, Peter J. Sabo, Stephen Hartman, Stylianos E. Antonarakis, Tae Hoon Kim, H. Kim, Baishali Maskeri, Thomas Royce, R. Luna, Sherman M. Weissman, Tim Hubbard, Oliver M. Dovey, Ewan Birney, Kate R. Rosenbloom, Robert M. Andrews, Damian Keefe, Arend Sidow, D. Zhou, Jane Grimwood, Ulas Karaoz, Zhiping Weng, H. Burden, Michael C. Zody, Hiram Clawson, Gerry Bouffard, S. van Calcar, Mark Dickson, Kevin Struhl, Ingeborg Holt, Emmanouil T. Dermitzakis, T. J. Vasicek, Peter J. Good, Charles R. Cantor, Hari Tammana, Josée Dostie, Prachi Shah, Elliott H. Margulies, Peter D. Ellis, Mark S. Guyer, Christopher M. Taylor, Patrick A. Navas, Dione Kampa, Colin N. Dewey, Lior Pachter, Christof Koch, George Asimenos, James R R Whittle, Gregory E. Crawford, Jane B. Lian, Pamela J. Thomas, Kazutoyo Osoegawa, Webb Miller, Chunxu Qu, Nele Gheldof, Keith D. James, Sandeep Patel, Todd Richmond, Jacquelyn R. Idol, Michael A. Singer, Tomoko M. Tabuchi, Adam Siepel, Yutao Fu, David Vetrie, Long H. Nguyen, Michael Snyder, William H. Majoros, Michael R. Brent, Nathan D. Trinklein, Leah O. Barrera, Mark Gerstein, Srinka Ghosh, Sara J. Hartman, Jade P. Vinson, C. L. Middle, Sambath Chung, George Stamatoyannopoulos, Y. Nakayama, George M. Church, Job Dekker, Olof Emanuelsson, Julien Lagarde, Roderic Guigó, Marco A. Marra, Jeremy Schmutz, Daryl J. Thomas, Yong Yu, M. R. McCormick, Xiang-Dong Fu, Richard Humbert, Jennifer L. Ashurst, Alexander E. Urban, Sarah Wilcox, Ghia Euskirchen, Michael Kamal, Cordelia Langford, Jacquie Schein, Gregory M. Cooper, Paul Bertone, Eric S. Lander, C. Ding, Antonio Piccolboni, Steven L. Salzberg, Rhonda Harrison, Matthew J. Oberley, E. A. Sekinger, Mihaela Pertea, Bing Ren, H. K. Kim, Roland Green, Shelley Force Aldred, Laura Elnitski, Michael Hawrylycz, Andrew J. Mungall, Kerstin Lindblad-Toh, David B. Jaffe, Andreas D. Baxevanis, L. Liefer, Michele Clamp, David Haussler, Jill Cheng, John L. Rinn, S. Kamholz, Vicki L. Wraight, H. Sethi, Francis S. Collins, Steven J.M. Jones, Serafim Batzoglou, P. J. De Jong, Matthew E. Portnoy, Stefan Bekiranov, M. McArthur, Shu-Jin Luo, Eric D. Green, Robert W. Blakesley, Tarjei S. Mikkelsen, Z. Ye, Pawandeep Dhami, Neerja Karnani
Publikováno v:
Science. 306:636-640
The ENCyclopedia Of DNA Elements (ENCODE) Project aims to identify all functional elements in the human genome sequence. The pilot phase of the Project is focused on a specified 30 megabases (∼1%) of the human genome sequence and is organized as an
Autor:
Clara K. Chan, Upal Basu-Roy, Denise Brooks, Anadulce Hernandez-Herrera, Nina Thiessen, Jinsong Liu, Yinghong Pan, Alka Mansukhani, Payal Sipahimalani, Yunfei Wen, Gordon Robertson, Jacquie Schein, Amy C. Rowat, Anil K. Sood, Andy Chu, Marco A. Marra, Steven J.M. Jones, Andrew J. Mungall, Emilia L. Lim, Preethi H. Gunaratne, Reanne Bowlby, Cristian Coarfa, Yussanne Ma, Chad V. Pecot, Xinna Zhang, Richard A. Moore, Lykke Pedersen, Sagar L. Patil
Publikováno v:
Oncotarget. 8:17406-17406
Autor:
Jacquie Schein, Barbara Robertson, Weiqing Li, Adrian Streit, Marco A. Marra, Ibrahim H. Kamal, William B. Wood
Publikováno v:
Genetics. 152:1573-1584
The masculinizing gene her-1 in Caenorhabditis elegans (Ce-her-1) encodes a novel protein, HER-1A, which is required for male development. To identify conserved elements in her-1 we have cloned and characterized two homologous nematode genes: one by