Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Jacqui Brener"'
Autor:
Jacqui Brener, Astrid Gall, Jacob Hurst, Rebecca Batorsky, Nora Lavandier, Fabian Chen, Anne Edwards, Chrissy Bolton, Reena Dsouza, Todd Allen, Oliver G. Pybus, Paul Kellam, Philippa C. Matthews, Philip J. R. Goulder
Publikováno v:
Retrovirology, Vol 15, Iss 1, Pp 1-13 (2018)
Abstract Background The factors determining differential HIV disease outcome among individuals expressing protective HLA alleles such as HLA-B*27:05 and HLA-B*57:01 remain unknown. We here analyse two HIV-infected subjects expressing both HLA-B*27:05
Externí odkaz:
https://doaj.org/article/5fc6d4b84d414835beab40dcb90f9e9a
Autor:
Paul Kellam, Philippa C Matthews, Todd M. Allen, Astrid Gall, Reena R. D’Souza, Jacqui Brener, Oliver G. Pybus, Nora Lavandier, Fabian Chen, Anne Edwards, Rebecca Batorsky, Jacob Hurst, Chrissy Bolton, Philip J. R. Goulder
Publikováno v:
Retrovirology, Vol 15, Iss 1, Pp 1-13 (2018)
Retrovirology
Retrovirology
Background The factors determining differential HIV disease outcome among individuals expressing protective HLA alleles such as HLA-B*27:05 and HLA-B*57:01 remain unknown. We here analyse two HIV-infected subjects expressing both HLA-B*27:05 and HLA-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98683002505acb3d7f005d8515c6244b
https://doi.org/10.1186/s12977-018-0390-9
https://doi.org/10.1186/s12977-018-0390-9
Autor:
Philip J. R. Goulder, Jacqui Brener, Claudia I. Juarez-Molina, Maribel Soto-Nava, Maximilian Muenchhoff, Santiago Ávila-Ríos, Ellen M. Leitman, Gustavo Reyes-Terán, Songee Branch, Humberto Valenzuela-Ponce, Clive Landis, Emily Adland, Rebecca Payne
Publikováno v:
Journal of Virology
Previous studies have demonstrated that effective cytotoxic T lymphocyte (CTL) responses drive the selection of escape mutations that reduce viral replication capacity (VRC). Escape mutations, including those with reduced VRC, can be transmitted and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3927cdb06f60274064c42a90aae310d5
https://doi.org/10.1128/jvi.01162-14
https://doi.org/10.1128/jvi.01162-14
Autor:
Ellen M, Leitman, Christina F, Thobakgale, Emily, Adland, M Azim, Ansari, Jayna, Raghwani, Andrew J, Prendergast, Gareth, Tudor-Williams, Photini, Kiepiela, Joris, Hemelaar, Jacqui, Brener, Ming-Han, Tsai, Masahiko, Mori, Lynn, Riddell, Graz, Luzzi, Pieter, Jooste, Thumbi, Ndung'u, Bruce D, Walker, Oliver G, Pybus, Paul, Kellam, Vivek, Naranbhai, Philippa C, Matthews, Astrid, Gall, Philip J R, Goulder
Publikováno v:
The Journal of Experimental Medicine
A major obstacle to an HIV cure in adult infection is a viral reservoir largely composed of CTL escape mutants. Leitman et al. demonstrate that in children, but not adults, escape variant–specific CTLs are generated that can successfully “corner
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f22454737887ba5d979d620761877642
https://pubmed.ncbi.nlm.nih.gov/28983013
https://pubmed.ncbi.nlm.nih.gov/28983013
Autor:
Jacqui Brener, Jacqueline A. Keane, Philip J. R. Goulder, Bridget Ferns, Martin Hunt, Thomas D. Otto, Swee Hoe Ong, Astrid Gall, Eleni Nastouli, Paul Kellam
Publikováno v:
Bioinformatics
Motivation: An accurate genome assembly from short read sequencing data is critical for downstream analysis, for example allowing investigation of variants within a sequenced population. However, assembling sequencing data from virus samples, especia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20135b74643ee651765d3a80d8357d35
https://eprints.gla.ac.uk/148001/1/148001.pdf
https://eprints.gla.ac.uk/148001/1/148001.pdf
Autor:
Philippa C Matthews, Paul Kellam, Rebecca Batorsky, Philip J. R. Goulder, Todd M. Allen, Søren Buus, Astrid Gall, Ellen M. Leitman, Jacqui Brener, Lynn Riddell
Publikováno v:
Europe PubMed Central
Retrovirology
Retrovirology
Background The precise immune responses mediated by HLA class I molecules such as HLA-B*27:05 and HLA-B*57:01 that protect against HIV disease progression remain unclear. We studied a CRF01_AE clade HIV infected donor-recipient transmission pair in w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41031d9fe3d6578ab6c52756eebc0325
https://doi.org/10.1186/s12977-015-0179-z
https://doi.org/10.1186/s12977-015-0179-z
Autor:
Henrik N, Kløverpris, Reuben, McGregor, James E, McLaren, Kristin, Ladell, Anette, Stryhn, Catherine, Koofhethile, Jacqui, Brener, Fabian, Chen, Lynn, Riddell, Luzzi, Graziano, Paul, Klenerman, Alasdair, Leslie, Søren, Buus, David A, Price, Philip, Goulder
Publikováno v:
AIDS (London, England)
Objectives: Although CD8+ T cells play a critical role in the control of HIV-1 infection, their antiviral efficacy can be limited by antigenic variation and immune exhaustion. The latter phenomenon is characterized by the upregulation of multiple inh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9b12857bced57f6f7bcf4e48262527b5
https://pubmed.ncbi.nlm.nih.gov/24906112
https://pubmed.ncbi.nlm.nih.gov/24906112