Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Jacques-Philippe Moulinoux"'
Autor:
Jérémy Ferrier, Mathilde Bayet-Robert, Bruno Pereira, Laurence Daulhac, Alain Eschalier, Denis Pezet, Jacques-Philippe Moulinoux, David Balayssac
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77828 (2013)
Oxaliplatin is an anticancer drug used for the treatment of advanced colorectal cancer, but it can also cause painful peripheral neuropathies. The pathophysiology of these neuropathies has not been yet fully elucidated, but may involve spinal N-methy
Externí odkaz:
https://doaj.org/article/fce4b4216cdc4b1b9189cacec2a2c77f
Publikováno v:
BioMedicine. 3:114-119
Background Polyamine (PA) dietary deprivation may be of clinical interest in castration-resistant prostate cancer (CRPC). Purpose We assessed tolerance and side effects of PA-free oral nutritional supplement (ONS) combined with partial intermittent i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4fca853e1126ea876b19e6d4225144a0
https://doi.org/10.1016/j.biomed.2013.04.005
https://doi.org/10.1016/j.biomed.2013.04.005
Publikováno v:
Biochemical Society Transactions. 31:384-387
Polyamine (PA) deprivation is effective in prostate carcinoma models. We have assessed the observance by patients, tolerance and side effects of a PA-reduced diet (PRD) and intestinal decontamination (ID), in order to reduce PA dietary and intestinal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7411390369cf7948861a666a5078d980
https://doi.org/10.1042/bst0310384
https://doi.org/10.1042/bst0310384
Autor:
Bénédicte Martin, Jean-Guy Delcros, François Carreaux, Francoise Posseme, Seiler N, Bertrand Carboni, Jacques-Philippe Moulinoux, Caroline Le Barbier
Publikováno v:
Bioorganic & Medicinal Chemistry. 10:2863-2871
Polyamine vectors are attractive for tumor targeting. We envisaged (Z)- 1,4-diamino-2-butene ( Z- DAB ), an unsaturated analogue of putrescine as vector of 10 B, 18 F and 131 I for boron neutron capture therapy (BNCT), and tumor imaging by positron e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a4cd16619e3f7ac7a9823b89bd7ba40
https://doi.org/10.1016/s0968-0896(02)00147-5
https://doi.org/10.1016/s0968-0896(02)00147-5
Autor:
Michel Vaultier, Johanne Homand, François Gaboriau, Michèle Saint-Pierre-Chazalet, Jacques-Philippe Moulinoux
Publikováno v:
Colloids and Surfaces B: Biointerfaces. 24:133-143
Structural analogues of the natural polyamines which contain a Si(CH 3 ) 2 group in the central carbon chain have previously been found to be cytostatic to various tumor cell lines and to inhibit tumor cell growth in experimentally-grafted animals. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::358611dab5c9015d9b57d62ae953da5a
https://doi.org/10.1016/s0927-7765(01)00226-0
https://doi.org/10.1016/s0927-7765(01)00226-0
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 47:33-43
Introduction: Reactive oxygen species (ROS) contribute to the development of pathophysiological processes, hence the increasing interest in modulating the antioxidant status of patient by nutritional or pharmacological intervention. Antioxidants act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd9d0374f06229029a4a3fff926136bc
https://doi.org/10.1016/s1056-8719(02)00187-9
https://doi.org/10.1016/s1056-8719(02)00187-9
Autor:
Jean Levêque, Fabrice Foucher, Jean-Yves Bansard, Rene Havouis, Jean-Yves Grall, Jacques-Philippe Moulinoux
Publikováno v:
Breast Cancer Research and Treatment. 60:99-105
Polyamines are involved in the development of breast cancer. We assayed polyamines in erythrocytes, urines, and breast tissues (tumor tissue and histologically normal breast tissue close to the tumor) of patients with invasive breast cancer (n = 174)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5668dca87feb90e7f676fc782718da1a
https://doi.org/10.1023/a:1006319818530
https://doi.org/10.1023/a:1006319818530
Autor:
M. Le Roch, Nathalie Bouillé, Julie Johnston, Jacques Renault, Jacques-Philippe Moulinoux, Isabelle Debroise, Jean-Guy Delcros, Anne Royou
Publikováno v:
Molecular Immunology. 36:93-102
The structural basis of the binding of the polyamine spermine to the monoclonal antibody SPM8-2 was studied using computer modelling, ELISA methods and chemical modifications of the binding site residues. Paratope modelling showed that the antibody c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2891b84d8bcfc0a08c46a804721dfb8f
https://doi.org/10.1016/s0161-5890(99)00025-5
https://doi.org/10.1016/s0161-5890(99)00025-5
Autor:
Véronique Quemener, Jacques-Philippe Moulinoux, B. Cipolla, Y. Blanchard, L Chamaillard, F. Guille, R. Havouis
Publikováno v:
Urological Research. 24:93-99
Polyamine deprivation in vivo produces significant tumor growth inhibition of the hormone-resistant, metastatic Dunning Mat-LyLu murine prostatic carcinoma. In order to produce a cytotoxic effect in addition to the cytostatic effect of polyamine depr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11858083fedb94618f905b693742e9fc
https://doi.org/10.1007/bf00431085
https://doi.org/10.1007/bf00431085
Autor:
Roselyne Primault, Lucie-Anne Martin, Naim Akhtar Khan, F. Darcel, Jacques-Philippe Moulinoux, Josette Lucas, Nikolaus Seiler, Véronique Quemener
Publikováno v:
Biology of the Cell. 77:195-199
In a previous study, we identified regions on the surface of tumor cells which act as acceptor sites for putrescine (Put) and studied the competition between structural analogs of Put (N,N'-tetramethyl-alpha,omega-diaminoalkanes) and Put bound to lat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::913204c6ad72d0c2ace83efc07d6fc78
https://doi.org/10.1016/s0248-4900(05)80188-1
https://doi.org/10.1016/s0248-4900(05)80188-1