Zobrazeno 1 - 10
of 250
pro vyhledávání: '"Jacques W.M. Lenders"'
Publikováno v:
Репродуктивная эндокринология, Iss 38, Pp 58-71 (2017)
Hypertension may be the initial clinical presentation for at least 15 endocrine disorders. An accurate diagnosis of endocrine hypertension provides clinicians with the opportunity to render a surgical cure or to achieve an optimal clinical response w
Externí odkaz:
https://doaj.org/article/23f46e46b1e8481aab851ca20ff4eb1c
Autor:
Christina Skondra, MD, Matthias Gruber, MD, Uwe Lindner, MD, Manuel Wilbring, MD, Joachim Nicolai, MD, Hans Jürgen Weitz, MD, Stefan R. Bornstein, MD, Graeme Eisenhofer, PhD, Lorenz C. Hofbauer, MD, Jacques W.M. Lenders, MD, PhD, FRCP
Publikováno v:
AACE Clinical Case Reports, Vol 2, Iss 1, Pp e25-e29 (2016)
ABSTRACT: Objective: Surgical management of critical ischemic heart disease in a patient with a pheochromocytoma poses a significant challenge for endocrinologists, surgeons, and anesthesiologists in terms of the sequence and optimal interval between
Externí odkaz:
https://doaj.org/article/d75f9e750f7f4e53bdde93240a15bf9a
Autor:
Roland Därr, Jacques W.M. Lenders, Lorenz C. Hofbauer, Bernd Naumann, Stefan R. Bornstein, Graeme Eisenhofer
Publikováno v:
Therapeutic Advances in Endocrinology and Metabolism, Vol 3 (2012)
Pheochromocytomas are rare endocrine tumors that can present insidiously and remain undiagnosed until death or onset of clear manifestations of catecholamine excess. They are often referred to as one of the ‘great mimics’ in medicine. These tumor
Externí odkaz:
https://doaj.org/article/96ab47ec384f4125ab9ab5359e6cb787
Autor:
Andrzej Januszewicz, Paolo Mulatero, Piotr Dobrowolski, Silvia Monticone, Patricia Van der Niepen, Pantelis Sarafidis, Martin Reincke, Emrush Rexhaj, Graeme Eisenhofer, Magdalena Januszewicz, Alexandros Kasiakogias, Reinhold Kreutz, Jacques W.M. Lenders, Maria Lorenza Muiesan, Alexandre Persu, Enrico Agabiti-Rosei, Rodrigo Soria, Mateusz Śpiewak, Aleksander Prejbisz, Franz H. Messerli
Publikováno v:
Journal of the American College of Cardiology. 80:1480-1497
Autor:
Georgiana Constantinescu, Manuel Schulze, Mirko Peitzsch, Thomas Hofmockel, Ute I. Scholl, Tracy Ann Williams, Jacques W.M. Lenders, Graeme Eisenhofer
Publikováno v:
Clinical Chemistry and Laboratory Medicine, 60, 12, pp. 1929-1937
Clinical Chemistry and Laboratory Medicine, 60, 1929-1937
Clinical Chemistry and Laboratory Medicine, 60, 1929-1937
Objectives Mass spectrometry-based steroidomics combined with machine learning (ML) provides a potentially powerful approach in endocrine diagnostics, but is hampered by limitations in the conveyance of results and interpretations to clinicians. We a
Autor:
Henri J.L.M. Timmers, Fred C.G.J. Sweep, Henricus P.M. Kunst, Arjen R. Mensenkamp, Ad R.M.M. Hermus, Jacques W.M. Lenders, Angelina G. Goudswaard, Benno Kusters, Nan Qin, Graeme Eisenhofer, Karel Pacak, Ron A. Wevers, Richard J.T. Rodenburg, Udo F.H. Engelke, Jyotsna U. Rao
Supplementary Figure 1 Examples of 1H NMR spectra for different genotypes A. Example of NMR spectrum of a sporadic tumor depicting the peak positions of lactic acid, acetic acid and catecholamines. B. Example of NMR spectrum of a SDHB tumor depicting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93b4e7f36498fde85425c773f15e2f0a
https://doi.org/10.1158/1078-0432.22447437.v1
https://doi.org/10.1158/1078-0432.22447437.v1
Autor:
Henri J.L.M. Timmers, Fred C.G.J. Sweep, Henricus P.M. Kunst, Arjen R. Mensenkamp, Ad R.M.M. Hermus, Jacques W.M. Lenders, Angelina G. Goudswaard, Benno Kusters, Nan Qin, Graeme Eisenhofer, Karel Pacak, Ron A. Wevers, Richard J.T. Rodenburg, Udo F.H. Engelke, Jyotsna U. Rao
Supplementary legend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02b6ff919beca05025dd012afd308857
https://doi.org/10.1158/1078-0432.22447434
https://doi.org/10.1158/1078-0432.22447434
Autor:
Mercedes Robledo, Anne-Paule Gimenez-Roqueplo, Graeme Eisenhofer, Giuseppe Opocher, Patricia L. M. Dahia, Massimo Mannelli, Karel Pacak, Felix Beuschlein, Miguel Urioste, Carli M.J. Tops, Henri J.L.M. Timmers, Elisa Taschin, Carlos Suarez, Alexander P.A. Stegmann, Frank Schillo, Macarena Ruiz-Ferrer, Giovanna Roncador, Nicole Reisch, Victoria Raymond, Elena Rapizzi, Nan Qin, Miguel Quesada-Charneco, Tamara Prodanov, Pierre-François Plouin, Peggy Pierre, Arnaud Murat, Luigi Mori, Anna Merlo, Arjen R. Mensenkamp, Rocío Letón, Jacques W.M. Lenders, Esther Korpershoek, Emiliano Honrado, Frederik J. Hes, Isabelle Guilhem, Álvaro Gómez-Graña, Encarna B. Gómez-García, Xavier Girerd, Tonino Ercolino, Ronald R. de Krijger, Mara Giacchè, Eleonora P.M. Corssmit, María-Dolores Chiara, Philippe Chanson, Maurizio Castellano, Salud Borrego, Sara Bobisse, Marinus J. Blok, Yves-Jean Bignon, Jérôme Bertherat, Sandra Bernaldo de Quirós, Marta Barontini, Laurence Amar, Aguirre A. de Cubas, Lucía Inglada-Pérez, Nasséra Abermil, Iñaki Comino-Méndez, Nicole Paes Morales, Francesca Schiavi, Alberto Cascón, Nelly Burnichon
Purpose: Pheochromocytomas (PCC) and paragangliomas (PGL) are genetically heterogeneous neural crest–derived neoplasms. Recently we identified germline mutations in a new tumor suppressor susceptibility gene, MAX (MYC-associated factor X), which pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e186187a379b455e8e5d962b4e1b154
https://doi.org/10.1158/1078-0432.c.6520958.v1
https://doi.org/10.1158/1078-0432.c.6520958.v1
Autor:
Henri J.L.M. Timmers, Fred C.G.J. Sweep, Henricus P.M. Kunst, Arjen R. Mensenkamp, Ad R.M.M. Hermus, Jacques W.M. Lenders, Angelina G. Goudswaard, Benno Kusters, Nan Qin, Graeme Eisenhofer, Karel Pacak, Ron A. Wevers, Richard J.T. Rodenburg, Udo F.H. Engelke, Jyotsna U. Rao
Purpose: Pheochromocytomas and paragangliomas (PGL) are neuroendocrine tumors of sympathetic and parasympathetic paraganglia. This study investigated the relationships between genotype-specific differences in mitochondrial function and catecholamine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::210db00b089c299d37bc60772e7448cc
https://doi.org/10.1158/1078-0432.c.6521073
https://doi.org/10.1158/1078-0432.c.6521073
Autor:
Jacques W.M. Lenders, Kristina Berke, Graeme Eisenhofer, Martin Reincke, Felix Beuschlein, Ulrich Dischinger, Aleksandra Kwapiszewska, Otilia Kimpel, Mirko Peitzsch, Svenja Nölting, Jimmy Masjkur, Martin Fassnacht, Aleksander Prejbisz, Stefan R. Bornstein, Georgiana Constantinescu, Piotr Dobrowolski
Publikováno v:
Journal of Clinical Endocrinology and Metabolism, 107, E1181-E1192
Journal of Clinical Endocrinology and Metabolism, 107, 3, pp. E1181-E1192
Journal of Clinical Endocrinology and Metabolism, 107, 3, pp. E1181-E1192
Context Most patients with adrenal incidentaloma have nonfunctional lesions that do not require treatment, while others have functional or malignant tumors that require intervention. The plasma steroid metabolome may be useful to assess therapeutic n