Zobrazeno 1 - 10
of 401
pro vyhledávání: '"Jacques Vasseur"'
Autor:
Diallo Traoré, Elisa Biecher, Manon Mallet, Sonia Rouanet, Dr. Jean‐Jacques Vasseur, Prof. Michael Smietana, Dr. Christelle Dupouy
Publikováno v:
ChemistryOpen, Vol 13, Iss 8, Pp n/a-n/a (2024)
Abstract We recently reported the properties of RNA hairpins constrained by a dimethylene (DME) disulfide (S−S) linker incorporated between two adjacent nucleosides in the loop and showed that this linker locked the hairpin conformation thus distur
Externí odkaz:
https://doaj.org/article/bb0e8db1315b4704969c64fe26eb9c19
Autor:
Sébastien Relier, Julie Ripoll, Hélène Guillorit, Amandine Amalric, Cyrinne Achour, Florence Boissière, Jérôme Vialaret, Aurore Attina, Françoise Debart, Armelle Choquet, Françoise Macari, Virginie Marchand, Yuri Motorin, Emmanuelle Samalin, Jean-Jacques Vasseur, Julie Pannequin, Francesca Aguilo, Evelyne Lopez-Crapez, Christophe Hirtz, Eric Rivals, Amandine Bastide, Alexandre David
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
The demethylase FTO was shown to remove on N6-methyladenosine (m6A) and N6, 2’-O-dimethyladenosine (m6Am) modifications on RNAs. Here the authors show that FTO impedes cancer stem cell-like abilities in colorectal cancer cells through its m6Am deme
Externí odkaz:
https://doaj.org/article/9446244d632a4b05a389d98461a70dd7
Autor:
Priscila Sutto-Ortiz, Sergey Tcherniuk, Nina Ysebaert, Pravien Abeywickrema, Mathieu Noël, Alice Decombe, Françoise Debart, Jean-Jacques Vasseur, Bruno Canard, Dirk Roymans, Peter Rigaux, Jean-François Eléouët, Etienne Decroly
Publikováno v:
PLoS Pathogens, Vol 17, Iss 5, p e1009562 (2021)
Respiratory syncytial virus (RSV) is a negative sense single-stranded RNA virus and one of the main causes of severe lower respiratory tract infections in infants and young children. RSV RNA replication/transcription and capping are ensured by the vi
Externí odkaz:
https://doaj.org/article/70047fcf48b749b8834adc4f16a949f7
Autor:
Kévan Pérez de Carvasal, Gérard Vergoten, Jean-Jacques Vasseur, Michael Smietana, François Morvan
Publikováno v:
Biomacromolecules
Biomacromolecules, 2023, 24 (2), pp.756-765. ⟨10.1021/acs.biomac.2c01203⟩
Biomacromolecules, 2023, 24 (2), pp.756-765. ⟨10.1021/acs.biomac.2c01203⟩
International audience; Inspired by automated DNA synthesis, electron-rich dialkoxynaphthalene (DAN) donor and electron-deficient naphthalene-tetracarboxylic diimide (NDI) acceptor phosphodiester-linked homohexamers were synthesized by the phosphoram
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 14, Iss 1, Pp 436-469 (2018)
Oligonucleotides (ONs) have been envisaged for therapeutic applications for more than thirty years. However, their broad use requires overcoming several hurdles such as instability in biological fluids, low cell penetration, limited tissue distributi
Externí odkaz:
https://doaj.org/article/940694118b764537a14dbeff710a2beb
Autor:
Kévan Pérez de Carvasal, Claudia Riccardi, Irene Russo Krauss, Domenico Cavasso, Jean-Jacques Vasseur, Michael Smietana, François Morvan, Daniela Montesarchio
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 17, p 9510 (2021)
In the search for optimized thrombin binding aptamers (TBAs), we herein describe the synthesis of a library of TBA analogues obtained by end-functionalization with the electron-rich 1,5-dialkoxy naphthalene (DAN) and the electron-deficient 1,8,4,5-na
Externí odkaz:
https://doaj.org/article/4390bee9df974d0190ef191ee8c4a146
Autor:
Fanny Leon, Elena Pinchon, Nevzat Temurok, François Morvan, Jean-Jacques Vasseur, Martine Clot, Vincent Foulongne, Jean-François Cantaloube, Philippe Vande Perre, Jean-Pierre Molès, Aurélien Daynès, Chantal Fournier-Wirth
Publikováno v:
Microorganisms, Vol 9, Iss 4, p 674 (2021)
Arbovirus diagnostics on blood from donors and travelers returning from endemic areas is increasingly important for better patient management and epidemiological surveillance. We developed a flexible approach based on a magnetic field-enhanced agglut
Externí odkaz:
https://doaj.org/article/ed74018ccc3d45e49927525f8e960438
Autor:
Romain Amador, Adrien Delpal, Bruno Canard, Jean-Jacques Vasseur, Etienne Decroly, Françoise Debart, Guillaume Clavé, Michael Smietana
Publikováno v:
Organic & Biomolecular Chemistry
Organic & Biomolecular Chemistry, 2022, 20 (38), pp.7582-7586. ⟨10.1039/d2ob01569b⟩
Organic & Biomolecular Chemistry, 2022, 20 (38), pp.7582-7586. ⟨10.1039/d2ob01569b⟩
International audience; N-Acylsulfonamides possess an additional carbonyl function compared to their sulfonamide analogues. Due to their unique physico-chemical properties, interest in molecules containing the N-acylsulfonamide moiety and especially
Autor:
Nathan Meyer, Jean-Marc Janot, Mathilde Lepoitevin, Michaël Smietana, Jean-Jacques Vasseur, Joan Torrent, Sébastien Balme
Publikováno v:
Biosensors, Vol 10, Iss 10, p 140 (2020)
Single nanopore is a powerful platform to detect, discriminate and identify biomacromolecules. Among the different devices, the conical nanopores obtained by the track-etched technique on a polymer film are stable and easy to functionalize. However,
Externí odkaz:
https://doaj.org/article/a347359b6329482ea08399c6052e0f40
Autor:
Marcel Hausdorff, Adrien Delpal, Sarah Barelier, Laura Nicollet, Bruno Canard, Franck Touret, Agathe Colmant, Bruno Coutard, Jean-Jacques Vasseur, Etienne Decroly, Françoise Debart
Publikováno v:
European Journal of Medicinal Chemistry
European Journal of Medicinal Chemistry, In press, ⟨10.1016/j.ejmech.2023.115474⟩
European Journal of Medicinal Chemistry, In press, ⟨10.1016/j.ejmech.2023.115474⟩
International audience; The COVID-19 pandemic reveals the urgent need to develop new therapeutics targeting the SARS-CoV-2 replication machinery. The first antiviral drugs were nucleoside analogues targeting RdRp and protease inhibitors active on nsp