Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Jacques Van Gompel"'
Autor:
Amanda Giddings, James Harvey, Michael Kranz, Wolfgang Muster, Franck A. Atienzar, Susanne Glowienke, Krista L. Dobo, Helga Gerets, Lewis Whitehead, Magnus Wilhelm Walter, James Reuberson, Mukesh Patel, Mick D. Fellows, Joerg Wichard, Hans-Peter Spirkl, Michelle O. Kenyon, Steve Swallow, Jordi Munoz-Muriedas, Matt Selby, Alexander Amberg, Robert A. Jolly, Anne-Laure Werner, Andreas Sutter, Frank Bringezu, David J. Yeo, Russell Naven, Jacques Van Gompel
Publikováno v:
Computational Toxicology. 7:27-35
Primary aromatic amines (pAAs) are attractive building blocks in medicinal chemistry programmes yet their potential for mutagenic activity causes real concern owing to the risk of genotoxicity-related drug attrition. In addition, despite the existenc
Autor:
Geert R. Verheyen, Barbara Weyn, Annelieke K. Peters, Gert Van de Wouwer, Philippe Vanparys, Jacques Van Gompel
Publikováno v:
Toxicology in Vitro. 22:1948-1956
The embryonic stem cell test (EST) is an ECVAM-validated assay to detect embryotoxicity. The output of the assay is the effect of test compounds on the differentiation of murine-derived embryonic stem cells (D3 cells), recorded by visual analysis of
Autor:
Matthias D'Hondt, Herwig Jansen, Ilse Koijen, Bart De Spiegeleer, Kirsten Vandercruyssen, Jacques Van Gompel, Elien Vangheluwe
Publikováno v:
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
During the stability evaluation of β-artemether containing finished drug products, a consistent and disproportional increase in the UV-peak areas of β-artemether degradation products, when compared to the peak area decline of β-artemether itself,