Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Jacques Van Cantfort"'
Publikováno v:
Biochemical and Biophysical Research Communications. 99:252-258
The intraperitoneal injection of the well known monooxygenase inducers (phenobarbital, β-naphtoflavone, pregnenolone-16α-carbonitrile, benzo(a)-pyrene, methylcholanthrene) elicits a net decrease in the specific binding of estradiol to its cytosol r
Autor:
Jacques Van Cantfort, Jacques Gielen
Publikováno v:
International Journal of Cancer. 19:538-545
In both the rat kidney and lung, inhalation of cigarette smoke diluted with air (1/15) for a limited period of time (15 min) specifically induces aryl hydrocarbon hydroxylase (AHH)2 in less than 4 h. Up to four successive inhalations administered at
Publikováno v:
European Journal of Biochemistry. 55:23-31
The establishement of the circadian rhythm of cholesterol 7α-hydroxylase activity requires protein and RNA synthesis. The spontaneous decrease of the enzymic activity, at the end of the night, allows us to evaluate a half-life time of about two hour
Autor:
Jacques Gielen, Jacques Van Cantfort
Publikováno v:
European Journal of Biochemistry. 55:33-40
70% of the microsome-bound cholesterol is directly accessible to cholesterol 7alpha-hydroxylase in an assay in vitro. After 5 min of incubation this endogenous cholesterol makes a single pool with the exogenously added substrate and modifies its spec
Publikováno v:
Biochemical Pharmacology. 34:1821-1826
The 7,8-epoxidation of benzo[ a ]pyrene, and the 9,10-epoxidation of benzo[ a ]-pyrene trans -7,8,-dihydrodiol coupled with covalent binding of the highly reactive diol-epoxide, are two key P-450-mediated reactions believed to be important in cancer
Publikováno v:
Archives of Toxicology. 36:255-266
Two microsomal steroid hydroxylase activities (cholesterol-7alpha-hydroxylase and progesterone-16alpha-hydroxylase) were measured in the livers of Sprague-Dawley and Wistar rats and compared to three other monooxygenase activities (aryl hydrocarbon h
Autor:
H. Barbason, Jacques Van Cantfort
Publikováno v:
European Journal of Cancer (1965). 11:531-536
The evolution of the division and specific tissular functions, in the liver, which are mutually exclusive of young and partially hepatectomised adult rats, was studied during hepatic carcinogenesis induced by the chronic administration of diethylnitr
Autor:
Jacques Van Cantfort
Publikováno v:
Life Sciences. 11:773-780
7-keto-cholesterol is a non-physiological compound usually formed in vitro during the incubation of cholesterol. Experimental data indicates that this substance does not derive from 7α-hydroxycholesterol. Therefore, its formation should not be taken
Autor:
Camille Heusghem, Jacques Van Cantfort
Publikováno v:
Biochemical Pharmacology. 22:3120-3122
Publikováno v:
Biochemical and biophysical research communications. 79(2)
By addition of two volumes of a 1M aqueous KOH/dimethylsulfoxide (1585; v/v) mixture to the enzymatic incubation medium, it is possible to selectively extract the unmetabolized benzo(a)pyrene in hexane. Therefore, the radio-activity remaining in the