Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Jacques R. Fresco"'
Autor:
Jacques R. Fresco, Maxwell P. Gold
Publikováno v:
Journal of Molecular Evolution. 85:84-98
The Alu element, the most prevalent SINE (short interspersed element) in the human genome, is one of the many RNA-encoding genes that evolved from the 7SL RNA gene. During analysis of the evolution of 7SL-derived RNAs, two distinct evolutionary inter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05145d5c1d5111f7e4c54e0b5e898a9c
https://doi.org/10.1007/s00239-017-9811-y
https://doi.org/10.1007/s00239-017-9811-y
Autor:
Jacques R. Fresco, Olga Amosova
Publikováno v:
Annual Review of Biochemistry. 86:461-484
Self-catalyzed DNA depurination is a sequence-specific physiological mechanism mediated by spontaneous extrusion of a stem-loop catalytic intermediate. Hydrolysis of the 5′G residue of the 5′GA/TGG loop and of the first 5′A residue of the 5′G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f5f05ff97f429f66fdf5e79a52befa2
https://doi.org/10.1146/annurev-biochem-070611-095951
https://doi.org/10.1146/annurev-biochem-070611-095951
Publikováno v:
Journal of Biological Chemistry. 288:11581-11589
The human β-globin gene contains an 18-nucleotide coding strand sequence centered at codon 6 and capable of forming a stem-loop structure that can self-catalyze depurination of the 5'G residue of that codon. The resultant apurinic lesion is subject
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8c9e1368b2279b6e8794490d2f46735
https://doi.org/10.1074/jbc.m113.454744
https://doi.org/10.1074/jbc.m113.454744
Publikováno v:
Journal of Biological Chemistry. 286:36316-36321
The sequence variation tolerated within the stem-loop-forming genomic consensus sequence for self-catalyzed site-specific depurination of G residues is explored. The variation in self-depurination kinetics with sequence changes in the loop residues a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f731923d50fefed44dc7e425d44a1806
https://doi.org/10.1074/jbc.m111.272047
https://doi.org/10.1074/jbc.m111.272047
Publikováno v:
Mutation research. 778
The human β-globin, δ-globin and ɛ-globin genes contain almost identical coding strand sequences centered about codon 6 having potential to form a stem-loop with a 5′GAGG loop. Provided with a sufficiently stable stem, such a structure can self-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::440a96a5dd2b3ab0198e6856a2e7eac5
https://pubmed.ncbi.nlm.nih.gov/26042536
https://pubmed.ncbi.nlm.nih.gov/26042536
Publikováno v:
Annals of the New York Academy of Sciences. 81:693-708
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83aafbd823f6c14f63a0986834ca93bd
https://doi.org/10.1111/j.1749-6632.1959.tb49351.x
https://doi.org/10.1111/j.1749-6632.1959.tb49351.x
Publikováno v:
Bioinformatics. 20:2251-2257
Motivation: Knowledge of how proteomic amino acid composition has changed over time is important for constructing realistic models of protein evolution and increasing our understanding of molecular evolutionary history. The proteomic amino acid compo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6792be43fff7b312ed9b564ff080febf
https://doi.org/10.1093/bioinformatics/bth235
https://doi.org/10.1093/bioinformatics/bth235
Publikováno v:
Nucleic Acids Research. 31:4673-4681
Three identical deoxyoligonucleotide third strands with a 3'-terminal psoralen moiety attached by linkers that differ in length (N = 16, 6 and 4 atoms) and structure were examined for their ability to form triplex-directed psoralen photoproducts with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2babfb65a9d9723f6c8171370b940e1
https://doi.org/10.1093/nar/gkg659
https://doi.org/10.1093/nar/gkg659
Autor:
Jacques R. Fresco, Dawn J. Brooks
Publikováno v:
Molecular & Cellular Proteomics. 1:125-131
Analysis of extant proteomes has the potential of revealing how amino acid frequencies within proteins have evolved over biological time. Evidence is presented here that cysteine, tyrosine, and phenylalanine residues have substantially increased in f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::751109a03df212a48d37297ebad9ef67
https://doi.org/10.1074/mcp.m100001-mcp200
https://doi.org/10.1074/mcp.m100001-mcp200
Autor:
Olga Amosova, Jacques R. Fresco
Publikováno v:
Nucleic Acids Research. 27:4632-4635
Eight base analogs were tested as third strand residues in otherwise homopyrimidine strands opposite each of the 'direct' (A.T and G.C) and 'inverted' (T.A and C.G) Watson-Crick base pairs, using UV melting profiles to assess triplex stability. The t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4889140226c65d3b0258cdfca558438
https://doi.org/10.1093/nar/27.23.4632
https://doi.org/10.1093/nar/27.23.4632