Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Jacques Pouyseggur"'
Autor:
Till Acker, Karl H. Plate, Jacques Pouyseggur, Ingo Flamme, Julia Wenner, Tanja Diem, Johanna Riedel, Anne-Theres Henze
Supplementary Materials, Table 1, Figure Legends 1-7 from Prolyl Hydroxylases 2 and 3 Act in Gliomas as Protective Negative Feedback Regulators of Hypoxia-Inducible Factors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::577a3e5b55fd7b746b347689adbf10c5
https://doi.org/10.1158/0008-5472.22382079.v1
https://doi.org/10.1158/0008-5472.22382079.v1
Autor:
Karl H. Plate, Julia Wenner, Johanna Riedel, Anne-Theres Henze, Ingo Flamme, Jacques Pouyseggur, Till Acker, Tanja Diem
Publikováno v:
Cancer research. 70(1)
Adaptive responses to hypoxia in tumors are transcriptionally regulated by the hypoxia inducible factors (HIF-1α/HIF-2α), which are tightly controlled by the HIF-prolyl hydroxylases (PHD). Hypoxia induces expression of the PHD2 and PHD3 proteins in