Zobrazeno 1 - 10
of 138 159
pro vyhledávání: '"Jacques P."'
Autor:
Wen Qi, Antoine Robert, Narcisse Singbo, Lucie Ratelle, Paul R. Fortin, Louis Bessette, Jacques P. Brown, Laëtitia Michou
Publikováno v:
Advances in Rheumatology, Vol 64, Iss 1, Pp 1-10 (2024)
Abstract Background In 2021, an EULAR task force published a definition of difficult-to-treat rheumatoid arthritis (D2T RA). Our current knowledge of D2T RA with the EULAR definition is based on European and Asian cohorts, and no North American cohor
Externí odkaz:
https://doaj.org/article/59546b365b1c4b6a8af7a9b00fa838ad
Autor:
Jenna C. Marek, Allison O. Dumitriu Carcoana, William J. West, III, Emily E. Weeden, Ajay Varadhan, Jessica Cobb, Sarah Cool, Gregory Fishberger, Collin B. Chase, Maykel Dolorit, Harrison E. Strang, Carla C. Moodie, Joseph R. Garrett, Jenna R. Tew, Jobelle Joyce-Anne R. Baldonado, Jacques P. Fontaine, Eric M. Toloza
Publikováno v:
Surgery in Practice and Science, Vol 18, Iss , Pp 100250- (2024)
Background: Marital status has been shown to have protective effects for married patients with various cancers. We sought to determine effects of marital status on perioperative outcomes after robotic-assisted pulmonary lobectomy (RAPL). Methods: We
Externí odkaz:
https://doaj.org/article/5292d8902f354b52b22459b99ff512b5
Autor:
Eli BenDavid, Sina Ramezanian, Yaoyao Lu, Joël Rousseau, Avi Schroeder, Marc Lavertu, Jacques P. Tremblay
Publikováno v:
Pharmaceuticals, Vol 17, Iss 6, p 763 (2024)
Prime editing shows potential as a precision genome editing technology, as well as the potential to advance the development of next-generation nanomedicine for addressing neurological disorders. However, turning in prime editors (PEs), which are macr
Externí odkaz:
https://doaj.org/article/09d0d33510234dd399a4bb216167add3
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 34, Iss , Pp 102040- (2023)
Therapeutic genome editing has the potential to cure diseases by directly correcting genetic mutations in tissues and cells. Recent progress in the CRISPR-Cas9 systems has led to breakthroughs in gene editing tools because of its high orthogonality,
Externí odkaz:
https://doaj.org/article/e234a86c012344dfa1a32221c9417299
Autor:
Allison O. Dumitriu Carcoana, Jenna C. Marek, William J. West, III, Cole R. Fiedler, William N. Doyle, Jr., Kristie M. Labib, Lauren C. Ladehoff, Jose A. Malavet, Gregory Fishberger, Carla C. Moodie, Joseph R. Garrett, Jenna R. Tew, Jobelle J.A.R. Baldonado, Jacques P. Fontaine, Eric M. Toloza
Publikováno v:
Surgery in Practice and Science, Vol 15, Iss , Pp 100210- (2023)
ABSTRACT: Background: Outcomes of lung cancer patients traveling greater distances for surgical oncology care are not well-described. We investigated the effects of increased travel burden after robotic-assisted pulmonary lobectomy (RAPL) for lung ca
Externí odkaz:
https://doaj.org/article/3b92b42eba3f44da80cec2e34d03136a
Autor:
Cedric Happi Mbakam, Joel Rousseau, Yaoyao Lu, Anne Bigot, Kamel Mamchaoui, Vincent Mouly, Jacques P. Tremblay
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 30, Iss , Pp 272-285 (2022)
Duchenne muscular dystrophy is a severe debilitating genetic disease caused by different mutations in the DMD gene leading to the absence of dystrophin protein under the sarcolemma. We used CRISPR-Cas9 prime editing technology for correction of the c
Externí odkaz:
https://doaj.org/article/53e3d0650e5c4b7db33a69417ae6c1a1
Changes in Perioperative Outcomes after Robotic-Assisted Pulmonary Lobectomy during the COVID-19 Era
Autor:
William N. Doyle, Jr, Diep Nguyen, William J. West, III, Cole R. Fiedler, Kristie M. Labib, Lauren Ladehoff, Allison O. Dumitriu Carcoana, Jenna C. Marek, Jose A. Malavet, Carla C. Moodie, Joseph R. Garrett, Jenna R. Tew, Jobelle J.A.R. Baldonado, Jacques P. Fontaine, Eric M. Toloza
Publikováno v:
Surgery in Practice and Science, Vol 13, Iss , Pp 100172- (2023)
Background: The COVID-19 pandemic presented patients with barriers to receiving healthcare. We sought to determine whether changes in healthcare access and practice during the pandemic affected perioperative outcomes after robotic-assisted pulmonary
Externí odkaz:
https://doaj.org/article/216daf1c7c574705ba628580e0ecc244
Autor:
Yang You, David Simonyan, Alexandre Bureau, Edith Gagnon, Caroline Albert, Jason R. Guertin, Jean-Eric Tarride, Jacques P. Brown, Laëtitia Michou
Publikováno v:
Bone Reports, Vol 18, Iss , Pp 101670- (2023)
Purpose: Paget's disease of bone (PDB) is a focal metabolic bone disorder characterized by an increased bone remodeling. Fifteen to 40 % of PDB patients have a familial form with an autosomal dominant inheritance. Disease-causing mutations of the SQS
Externí odkaz:
https://doaj.org/article/9395a491a03e49349b06c32f9c82d3e9
Publikováno v:
Cells, Vol 13, Iss 1, p 31 (2023)
We report the first correction from prime editing a mutation in the RYR1 gene, paving the way to gene therapies for RYR1-related myopathies. The RYR1 gene codes for a calcium channel named Ryanodine receptor 1, which is expressed in skeletal muscle f
Externí odkaz:
https://doaj.org/article/91aef639e2f445d0bd1581be4b1b97ad
Autor:
Cedric Happi Mbakam, Jeanne Roustant, Joel Rousseau, Pouire Yameogo, Yaoyao Lu, Anne Bigot, Kamel Mamchaoui, Vincent Mouly, Gabriel Lamothe, Jacques P. Tremblay
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
Duchenne muscular dystrophy is a rare and lethal hereditary disease responsible for progressive muscle wasting due to mutations in the DMD gene. We used the CRISPR-Cas9 Prime editing technology to develop different strategies to correct frameshift mu
Externí odkaz:
https://doaj.org/article/a835f08bd75b4b848f7c08256e27f334