Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Jacques Mizon"'
Publikováno v:
Biochimie. 85:101-107
Bikunin (Bk) is a Künitz-type serine proteinase inhibitor, which occurs in human plasma, mainly as covalent complexes with one or two of the three peptide heavy chains. The leading member of this glycoprotein family is inter-alpha-inhibitor (I alpha
Publikováno v:
European Journal of Biochemistry. 268:2717-2724
Inter-alpha-inhibitor (IalphaI) and pre-alpha-inhibitor (PalphaI) are the main members of a set of multichain serine proteinase inhibitors. Present in human plasma, they may be involved in control of the inflammatory process. They are composed of hom
Publikováno v:
European Journal of Biochemistry. 268:544-553
The inter-alpha-inhibitor (I alpha I) family gathers together several plasma protease inhibitors such as I alpha I and pre-alpha-inhibitor (P alpha I) that are variously assembled from a set of polypeptide chain precursors designated H1P to H3P. In a
Autor:
François Fourrier, Antoine Tournoys, Mercé Jourdain, Malika Balduyck, Jacques Mizon, Charlotte Mizon, Herve Drobecq, Dalila Albani
Publikováno v:
Journal of Laboratory and Clinical Medicine. 135:188-198
Inter-alpha-inhibitor (IalphaI) is a human plasma serine proteinase inhibitor. It contains one light peptide chain called bikunin that exerts antiproteinase activity and other antiinflammatory functions. Bikunin is covalently linked to two heavy chai
Autor:
Mercé Jourdain, Jacques Mizon, François Fourrier, Jenny Goudemand, Antoine Tournoys, Claude Chopin, J. Mangalaboyi, Odile Carrette, Charlotte Mizon
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 156:1825-1833
We investigated the effects of human inter-alpha-inhibitor (I alpha I) on hemodynamics, oxygenation, and coagulation parameters in a porcine model of endotoxic shock. Four groups of six animals were studied: (1) control, (2) I alpha I group receiving
Publikováno v:
Digestive Diseases and Sciences. 42:817-822
Digestive bacterial microflora play a major rolein the pathogenesis of Crohn's disease (CD). Bacterialenzyme activities, especially β-D-galactosidase,are decreased in fecal extracts from CD patients. We hypothesized that an alteration of thecolonic
Publikováno v:
Journal of Microbiological Methods. 27:25-31
Bacterial glycosidase activities, specially β-galactosidase (β-gal), are reduced in faeces from patients with Crohn's disease (CD). In order to test the hypothesis that an alteration of the colonic flora might be responsible for decreased faecal β
Autor:
C Mizon, Antoine Cortot, Jacques Mizon, Christel Neut, O Carrette, Jean-Frederic Colombel, C. Favier
Publikováno v:
Digestive Diseases and Sciences. 40:2641-2646
Enzymes produced by colonic microflora have been proposed for triggering local delivery of antiinflammatory azo-bond drugs and prodrugs to the colon. This approach could be advantageous in steroid treatment of inflammatory bowel diseases, thus sparin
Autor:
Catherine Michalski, Thierry Burnouf, Frank Piva, Jacques Mizon, Charlotte Mizon, Jean-Jacques Huart, Malika Balduyck
Publikováno v:
Vox Sanguinis. 67:329-336
Inter-alpha-trypsin inhibitor (ITI) is a serine protease inhibitor found in human plasma. Its antiprotease activity is due to bikunin which is effective in various types of experimental shock and pancreatitis. Therefore ITI, which releases bikunin by
Autor:
Catherine Michalski, Bernard Fournet, Mostapha Kouach, Willy Morelle, Pierre Sautière, Calliope Capon, Malika Balduyck, Jacques Mizon
Publikováno v:
European Journal of Biochemistry. 221:881-888
Inter-alpha-trypsin inhibitor (ITI) is a tight complex of three different proteins: bikunin and two heavy chains H1 and H2. In order to demonstrate that the three chains are covalently linked by a chondroitin sulphate chain as previously proposed [En