Zobrazeno 1 - 10 of 142 pro vyhledávání: '"Jacques Medioni"'
1
Akademický článek
Retrospective analysis of real-world data to evaluate actionability of a comprehensive molecular profiling panel in solid tumor tissue samples (REALM study).
Autor: Karen Leroy, Clarisse Audigier Valette, Jérôme Alexandre, Lise Boussemart, Jean Chiesa, Clotilde Deldycke, Carlos Gomez-Rocca, Antoine Hollebecque, Jacqueline Lehmann-Che, Antoinette Lemoine, Sandrine Mansard, Jacques Medioni, Isabelle Monnet, Samia Mourah, Thomas Pierret, Dominique Spaëth, Alexandre Civet, Sandrine Galoin, Antoine Italiano
Publikováno v: PLoS ONE, Vol 18, Iss 9, p e0291495 (2023)
IntroductionConsidering the growing interest in matched cancer treatment, our aim was to evaluate the ability of a comprehensive genomic profiling (CGP) assay to propose at least one targeted therapy given an identified genomic alteration or signatur
Externí odkaz: https://doaj.org/article/8bec3a2beb214f7a869dd1f1edcdeb6c
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2
Akademický článek
Association between Olaparib Exposure and Early Toxicity in BRCA-Mutated Ovarian Cancer Patients: Results from a Retrospective Multicenter Study
Autor: Maud Velev, Alicja Puszkiel, Benoit Blanchet, Sixtine de Percin, Nicolas Delanoy, Jacques Medioni, Claire Gervais, David Balakirouchenane, Nihel Khoudour, Patricia Pautier, Alexandra Leary, Zahra Ajgal, Laure Hirsch, François Goldwasser, Jerome Alexandre, Guillaume Beinse
Publikováno v: Pharmaceuticals, Vol 14, Iss 8, p 804 (2021)
Factors associated with olaparib toxicity remain unknown in ovarian cancer patients. The large inter-individual variability in olaparib pharmacokinetics could contribute to the onset of early significant adverse events (SAE). We aimed to retrospectiv
Externí odkaz: https://doaj.org/article/58923e84ca98466e86ca7b10c494bf84
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3
Akademický článek
Innovative design for a phase 1 trial with intra-patient dose escalation: The Crotoxin study
Autor: Jacques Medioni, Mara Brizard, Reza Elaidi, Paul F. Reid, Khadija Benlhassan, Dorothy Bray
Publikováno v: Contemporary Clinical Trials Communications, Vol 7, Iss , Pp 186-188 (2017)
Introduction: Crotoxin has a broad antitumor activity but has shown frequent neurotoxic toxicity. To induce tolerance and limit this toxicity, we propose a new design with intra-patient dose escalation. Methods: A new Dose Limiting Toxicity definitio
Externí odkaz: https://doaj.org/article/11519776c03a48f78a14cdffc55318b0
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4
Benefits of Homeopathic Complementary Treatment in Patients With Breast Cancer: A Retrospective Cohort Study Based on the French Nationwide Healthcare Database
Autor: Jacques Medioni, Daniel Scimeca, Yecenia Lopez Marquez, Emmanuelle Leray, Marie Dalichampt, Nicolas Hoertel, Mohammed Bennani, Pascal Trempat, Naoual Boujedaini
Publikováno v: Clinical Breast Cancer
Clinical Breast Cancer, 2022, ⟨10.1016/j.clbc.2022.10.001⟩
International audience; BackgroundComplementary therapy in oncology aims to help patients better cope with the illness and side effects (SEs) of cancer treatments that affect their quality of life (QOL). This study aimed to assess the benefits of hom
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a476f5d8efa393fc2be0c8c10d9b0266
https://doi.org/10.1016/j.clbc.2022.10.001
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