Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Jacques J Picard"'
Autor:
Nata Y S-G Diman, Sophie Remacle, Nicolas Bertrand, Jacques J Picard, Stéphane Zaffran, René Rezsohazy
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27624 (2011)
A transgenic mouse line harbouring a β-galacdosidase reporter gene controlled by the proximal 2 kb promoter of Hoxa3 was previously generated to investigate the regulatory cues governing Hoxa3 expression in the mouse. Examination of transgenic embry
Externí odkaz:
https://doaj.org/article/90b2d26c803d4161b1e1ee8f6eb924ee
Autor:
Sophie Remacle, Omar Abdel O.A. Samad, Xavier Lampe, Jacques J. Picard, Allan Guiguen, René Rezsohazy, Filippo F.M. Rijli, Christelle Matis
Publikováno v:
Nucleic acids research, 36 (10
Nucleic Acids Research
Nucleic Acids Research, 2008, 36 (10), pp.3214-25. ⟨10.1093/nar/gkn148⟩
Nucleic Acids Research, Oxford University Press, 2008, 36 (10), pp.3214-25. ⟨10.1093/nar/gkn148⟩
Nucleic Acids Research, Vol. 36, no. 10, p. 3214-25 (2008)
Nucleic Acids Research
Nucleic Acids Research, 2008, 36 (10), pp.3214-25. ⟨10.1093/nar/gkn148⟩
Nucleic Acids Research, Oxford University Press, 2008, 36 (10), pp.3214-25. ⟨10.1093/nar/gkn148⟩
Nucleic Acids Research, Vol. 36, no. 10, p. 3214-25 (2008)
The Hoxa2 gene has a fundamental role in vertebrate craniofacial and hindbrain patterning. Segmental control of Hoxa2 expression is crucial to its function and several studies have highlighted transcriptional regulatory elements governing its activit
Autor:
Jacques J. Picard, Mehdi Maleki, René Rezsohazy, Philippe Delahaut, Pierre Henri Deprez, Laurent Massip, Benoît Lengelé, Catherine Behets, F. Ectors
Publikováno v:
Differentiation. 75:256-267
Vertebrate Hox genes act as developmental architects by patterning embryonic structures like axial skeletal elements, limbs, brainstem territories, or neural crest derivatives. While active during the patterning steps of development, these genes turn
Autor:
Jacques J. Picard, Sophie Remacle, René Rezsohazy, Xavier Lampe, Christelle Matis, Filippo F.M. Rijli, Françoise Gofflot, Franck Oury
Publikováno v:
Developmental Dynamics
Developmental Dynamics, Wiley, 2007, 236 (9), pp.2675-84. ⟨10.1002/dvdy.21266⟩
Developmental Dynamics, Wiley, 2007, 236 (9), pp.2675-84. ⟨10.1002/dvdy.21266⟩
The embryonic functions of Hox proteins have been extensively investigated in several animal phyla. These transcription factors act as selectors of developmental programmes, to govern the morphogenesis of multiple structures and organs. However, desp
Publikováno v:
Reproductive Toxicology. 20:39-45
Several embryotoxic agents, which includes sodium salicylate, were reported to induce vertebral variations in the form of supernumerary ribs (SNR) when administered to pregnant rodents. Because the biological significance of SNR in toxicological stud
Publikováno v:
Diabetologia. 46:1245-1251
Aims/hypothesis. Maternal diabetes mellitus increases the risk for fetal malformations. Several of these malformations are found in organs and tissues derived from the neural crest. Previous studies have shown changes in fetal organs of neural crest
Autor:
Jacques J. Picard, Charles Roux, Claude Wolf, Françoise Chevy, Françoise Illien, Carine Hars, Françoise Gofflot
Publikováno v:
Human Molecular Genetics. 12:1187-1198
Human disorders caused by inborn errors of cholesterol biosynthesis are characterized by dysmorphogenesis of multiple organs. This includes limb malformations that are observed at high frequency in some disorders, such as the Smith-Lemli-Opitz syndro
Autor:
Michael G. Narotsky, Jacques J. Picard, Nathalie Pacico, Françoise Gofflot, Nathalie Wéry, Robert J. Kavlock
Publikováno v:
Birth Defects Research Part A: Clinical and Molecular Teratology. 67:59-67
BACKGROUND: Previously, we showed that prenatal exposure to boric acid (BA), an industrial agent with large production, causes alterations of the axial skeleton in rat embryos, reminiscent of homeotic transformations. Indeed, Sprague-Dawley rats expo
Publikováno v:
Developmental Dynamics. 220:99-111
Holoprosencephaly is a common developmental anomaly of the forebrain and midface, that has been associated with mutations in the Sonic Hedgehog gene, and with perturbations of cholesterol synthesis and metabolism in mammalian embryos. The study prese
Publikováno v:
Mammalian Genome. 11:696-699