Endogenous phosphorylation of the GABAA receptor protein is counteracted by a membrane-associated phosphatase

Autor: Frédéric Minier, Michel H. Bureau, Jacques J. Laschet, Bertrand Evrard

Publikováno v: Neurochemistry International. 36:499-506

Incubation of bovine brain membranes with [γ- 33 P]ATP phosphorylated mainly a 51-kDa band. Electrophoretic co-migration was observed for 33 P- and [ 3 H]flunitrazepam-labeled bands in both membrane fractions and in affinity-purified GABA A receptor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5367e89e917261340ef03efdbc0db2f2
https://doi.org/10.1016/s0197-0186(99)00158-8

GluN2C selective inhibition is a target to develop new antiepileptic compounds.

Autor: Gataullina S; Service D'explorations Fonctionnelles Multidisciplinaires, Centre de médecine du sommeil, Antoine Béclère Hospital, APHP, Université Paris Saclay, Clamart, France., Galvani G; AdPueriVitam (APV), Antony, France., Touchet S; L2CM, CNRS UMR 7053, Université de Lorraine, Nancy, France., Nous C; Institut de la Vision, UFR Sciences et Technologies, Paris, France., Lemaire É; AdPueriVitam (APV), Antony, France., Laschet J; LCA, Laschet Consult & Analysis SAS, Angerville, France., Chiron C; INSERM U1141, Paris, France.; Neuropediatrics Department, Necker Hospital, APHP, Paris, France., Dulac O; AdPueriVitam (APV), Antony, France., Dossi E; Center for Interdisciplinary Research in Biology, Collège de France, CNRS UMR 7241, INSERM U1050, Université PSL, Paris, France., Brion JD; CNRS UMR 8076, BioCIS, Université Paris-Saclay, Châtenay-Malabry, France., Messaoudi S; CNRS UMR 8076, BioCIS, Université Paris-Saclay, Châtenay-Malabry, France., Alami M; CNRS UMR 8076, BioCIS, Université Paris-Saclay, Châtenay-Malabry, France., Huberfeld G; Center for Interdisciplinary Research in Biology, Collège de France, CNRS UMR 7241, INSERM U1050, Université PSL, Paris, France.; Neurology Department, Hôpital Fondation Adolphe de Rothschild, Paris, France.

Publikováno v: Epilepsia [Epilepsia] 2022 Nov; Vol. 63 (11), pp. 2911-2924. Date of Electronic Publication: 2022 Sep 11.

Autism spectrum disorder and cognitive profile in children with Dravet syndrome: Delineation of a specific phenotype.

Autor: Ouss L; Reference Centre for Rare Epilepsies Department of Pediatric Neurology Necker Enfants Malades Hospital APHP Paris Descartes University Imagine Institute Paris France.; Child Psychiatry Unit Necker Enfants Malades Hospital Paris France., Leunen D; Reference Centre for Rare Epilepsies Department of Pediatric Neurology Necker Enfants Malades Hospital APHP Paris Descartes University Imagine Institute Paris France.; Child Psychiatry Unit Necker Enfants Malades Hospital Paris France., Laschet J; Reference Centre for Rare Epilepsies Department of Pediatric Neurology Necker Enfants Malades Hospital APHP Paris Descartes University Imagine Institute Paris France., Chemaly N; Reference Centre for Rare Epilepsies Department of Pediatric Neurology Necker Enfants Malades Hospital APHP Paris Descartes University Imagine Institute Paris France., Barcia G; Department of Medical Genetics Necker Enfants Malades Hospital APHP Paris France., Losito EM; Reference Centre for Rare Epilepsies Department of Pediatric Neurology Necker Enfants Malades Hospital APHP Paris Descartes University Imagine Institute Paris France., Aouidad A; Department of Child and Adolescent Psychiatry APHP Pitié-Salpêtrière Hospital Paris France., Barrault Z; Reference Centre for Rare Epilepsies Department of Pediatric Neurology Necker Enfants Malades Hospital APHP Paris Descartes University Imagine Institute Paris France., Desguerre I; Reference Centre for Rare Epilepsies Department of Pediatric Neurology Necker Enfants Malades Hospital APHP Paris Descartes University Imagine Institute Paris France., Breuillard D; Reference Centre for Rare Epilepsies Department of Pediatric Neurology Necker Enfants Malades Hospital APHP Paris Descartes University Imagine Institute Paris France., Nabbout R; Reference Centre for Rare Epilepsies Department of Pediatric Neurology Necker Enfants Malades Hospital APHP Paris Descartes University Imagine Institute Paris France.

Publikováno v: Epilepsia open [Epilepsia Open] 2018 Dec 20; Vol. 4 (1), pp. 40-53. Date of Electronic Publication: 2018 Dec 20 (Print Publication: 2019).

Patients with dravet syndrome in the era of stiripentol: A French cohort cross-sectional study.

Autor: De Liso P; Reference Centre for Rare Epilepsies, Department of Pediatric Neurology, Necker Enfants Malades Hospital, Imagine Institute, 149 Rue de Sevres, 75015 Paris, France; Department of Pediatrics and Child Neuropsychiatry, Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy. Electronic address: paola.deliso@uniroma1.it., Chemaly N; Reference Centre for Rare Epilepsies, Department of Pediatric Neurology, Necker Enfants Malades Hospital, Imagine Institute, 149 Rue de Sevres, 75015 Paris, France; Inserm U1129, Hôpital Necker-Enfants Malades, 149 Rue de Sèvres, 75015 Paris, France; CEA, Gif Sur Yvette, France; Paris Descartes University, Department of Pediatrics, Hôpital Necker-Enfants Malades, 149 Rue de Sèvres, 75015 Paris, France. Electronic address: nicole.chemaly@aphp.fr., Laschet J; Inserm U1129, Hôpital Necker-Enfants Malades, 149 Rue de Sèvres, 75015 Paris, France; CEA, Gif Sur Yvette, France; Paris Descartes University, Department of Pediatrics, Hôpital Necker-Enfants Malades, 149 Rue de Sèvres, 75015 Paris, France. Electronic address: jacques.laschet@inserm.fr., Barnerias C; Reference Centre for Rare Epilepsies, Department of Pediatric Neurology, Necker Enfants Malades Hospital, Imagine Institute, 149 Rue de Sevres, 75015 Paris, France. Electronic address: christine.barnerias@aphp.fr., Hully M; Reference Centre for Rare Epilepsies, Department of Pediatric Neurology, Necker Enfants Malades Hospital, Imagine Institute, 149 Rue de Sevres, 75015 Paris, France; Inserm U1129, Hôpital Necker-Enfants Malades, 149 Rue de Sèvres, 75015 Paris, France; CEA, Gif Sur Yvette, France; Paris Descartes University, Department of Pediatrics, Hôpital Necker-Enfants Malades, 149 Rue de Sèvres, 75015 Paris, France. Electronic address: marie.hully@aphp.fr., Leunen D; Reference Centre for Rare Epilepsies, Department of Pediatric Neurology, Necker Enfants Malades Hospital, Imagine Institute, 149 Rue de Sevres, 75015 Paris, France; Inserm U1129, Hôpital Necker-Enfants Malades, 149 Rue de Sèvres, 75015 Paris, France; CEA, Gif Sur Yvette, France; Paris Descartes University, Department of Pediatrics, Hôpital Necker-Enfants Malades, 149 Rue de Sèvres, 75015 Paris, France. Electronic address: dorothee.leunen@aphp.fr., Desguerre I; Reference Centre for Rare Epilepsies, Department of Pediatric Neurology, Necker Enfants Malades Hospital, Imagine Institute, 149 Rue de Sevres, 75015 Paris, France; Paris Descartes University, Department of Pediatrics, Hôpital Necker-Enfants Malades, 149 Rue de Sèvres, 75015 Paris, France. Electronic address: isabelle.desguerre@aphp.fr., Chiron C; Reference Centre for Rare Epilepsies, Department of Pediatric Neurology, Necker Enfants Malades Hospital, Imagine Institute, 149 Rue de Sevres, 75015 Paris, France; Inserm U1129, Hôpital Necker-Enfants Malades, 149 Rue de Sèvres, 75015 Paris, France; CEA, Gif Sur Yvette, France. Electronic address: catherine.chiron@aphp.fr., Dulac O; Reference Centre for Rare Epilepsies, Department of Pediatric Neurology, Necker Enfants Malades Hospital, Imagine Institute, 149 Rue de Sevres, 75015 Paris, France; Inserm U1129, Hôpital Necker-Enfants Malades, 149 Rue de Sèvres, 75015 Paris, France; CEA, Gif Sur Yvette, France. Electronic address: olivier.dulac@aphp.fr., Nabbout R; Reference Centre for Rare Epilepsies, Department of Pediatric Neurology, Necker Enfants Malades Hospital, Imagine Institute, 149 Rue de Sevres, 75015 Paris, France; Inserm U1129, Hôpital Necker-Enfants Malades, 149 Rue de Sèvres, 75015 Paris, France; CEA, Gif Sur Yvette, France; Paris Descartes University, Department of Pediatrics, Hôpital Necker-Enfants Malades, 149 Rue de Sèvres, 75015 Paris, France. Electronic address: rima.nabbout@aphp.fr.

Publikováno v: Epilepsy research [Epilepsy Res] 2016 Sep; Vol. 125, pp. 42-6. Date of Electronic Publication: 2016 May 28.

Dysembryoplastic neuroepithelial tumors: epileptogenicity related to histologic subtypes.

Autor: Chassoux F; Department of Neurosurgery, Sainte-Anne Hospital, 75014 Paris, France. f.chassoux@ch-sainte-anne.fr, Landré E, Mellerio C, Laschet J, Devaux B, Daumas-Duport C

Publikováno v: Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology [Clin Neurophysiol] 2013 Jun; Vol. 124 (6), pp. 1068-78. Date of Electronic Publication: 2012 Dec 29.