Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Jacques I Wadiche"'
Autor:
Elena W Adlaf, Ryan J Vaden, Anastasia J Niver, Allison F Manuel, Vincent C Onyilo, Matheus T Araujo, Cristina V Dieni, Hai T Vo, Gwendalyn D King, Jacques I Wadiche, Linda Overstreet-Wadiche
Publikováno v:
eLife, Vol 11 (2022)
Externí odkaz:
https://doaj.org/article/48d004974e794fb688597ec2f737a32a
Autor:
Ryan J Vaden, Jose Carlos Gonzalez, Ming-Chi Tsai, Anastasia J Niver, Allison R Fusilier, Chelsea M Griffith, Richard H Kramer, Jacques I Wadiche, Linda Overstreet-Wadiche
Publikováno v:
eLife, Vol 9 (2020)
Parvalbumin-expressing interneurons (PVs) in the dentate gyrus provide activity-dependent regulation of adult neurogenesis as well as maintain inhibitory control of mature neurons. In mature neurons, PVs evoke GABAA postsynaptic currents (GPSCs) with
Externí odkaz:
https://doaj.org/article/325209460c5c45cfac84313a7ec71f89
Autor:
Jada H Vaden, Gokulakrishna Banumurthy, Eugeny S Gusarevich, Linda Overstreet-Wadiche, Jacques I Wadiche
Publikováno v:
eLife, Vol 8 (2019)
The number of neurotransmitter-filled vesicles released into the synaptic cleft with each action potential dictates the reliability of synaptic transmission. Variability of this fundamental property provides diversity of synaptic function across brai
Externí odkaz:
https://doaj.org/article/2f81f514aee84687b2055776f0507be6
Publikováno v:
eLife, Vol 6 (2017)
Golgi cells are the principal inhibitory neurons at the input stage of the cerebellum, providing feedforward and feedback inhibition through mossy fiber and parallel fiber synapses. In vivo studies have shown that Golgi cell activity is regulated by
Externí odkaz:
https://doaj.org/article/5723d950e29949cbb4d7f6843b83a5b4
Autor:
Elena W Adlaf, Ryan J Vaden, Anastasia J Niver, Allison F Manuel, Vincent C Onyilo, Matheus T Araujo, Cristina V Dieni, Hai T Vo, Gwendalyn D King, Jacques I Wadiche, Linda Overstreet-Wadiche
Publikováno v:
eLife, Vol 6 (2017)
Adult-born neurons are continually produced in the dentate gyrus but it is unclear whether synaptic integration of new neurons affects the pre-existing circuit. Here we investigated how manipulating neurogenesis in adult mice alters excitatory synapt
Externí odkaz:
https://doaj.org/article/1742315f915a44d686adaa1ef0fa6d67
Autor:
Phyllis C Pugh, Elena W Adlaf, Chaunsheng eZhao, Sean J Markwardt, Cristin F Gavin, Jacques I Wadiche, Linda eOverstreet-Wadiche
Publikováno v:
Frontiers in Neuroscience, Vol 5 (2011)
The production and integration of adult-generated neurons in the dentate gyrus is dramatically perturbed by a variety of pathological insults, including repetitive seizures and hypoxia/ischemia. Less is known about how insults affect early postnatal
Externí odkaz:
https://doaj.org/article/fb21aaca1e7c4f32aa80c87dd31cb5f4
Autor:
Reagan L. Pennock, Luke T. Coddington, Xiaohui Yan, Linda Overstreet-Wadiche, Jacques I. Wadiche
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Precise alignment of pre- and postsynaptic elements optimizes the activation of glutamate receptors at excitatory synapses. Nonetheless, glutamate that diffuses out of the synaptic cleft can have actions at distant receptors, a mode of trans
Externí odkaz:
https://doaj.org/article/7ae40411316e4b6b8cb2ac22171ce8fa
Autor:
Jose Carlos Gonzalez, Haeun Lee, Angela M. Vincent, Angela L. Hill, Lacy K. Goode, Gwendalyn D. King, Karen L. Gamble, Jacques I. Wadiche, Linda Overstreet-Wadiche
Publikováno v:
Cell Reports, Vol 42, Iss 2, Pp 112039- (2023)
Summary: The central circadian regulator within the suprachiasmatic nucleus transmits time of day information by a diurnal spiking rhythm driven by molecular clock genes controlling membrane excitability. Most brain regions, including the hippocampus
Externí odkaz:
https://doaj.org/article/25eaad8544744f28b4471562f31e713a
Autor:
Cristina V. Dieni, Roberto Panichi, James B. Aimone, Chay T. Kuo, Jacques I. Wadiche, Linda Overstreet-Wadiche
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Immature dentate gyrus neurons are highly excitable and are thought to be more responsive to afferent activity than mature neurons. Here, the authors find stimulation of the entorhinal cortex paradoxically generates spiking in mature rather than imma
Externí odkaz:
https://doaj.org/article/20e517ec89bc4a7fbd349a98671c418c
Autor:
Jose Carlos Gonzalez, Haeun Lee, Angela M Vincent, Lacy K Goode, Gwendalyn D King, Karen L Gamble, Jacques I Wadiche, Linda Overstreet-Wadiche
SummaryThe central circadian regulator within the suprachiasmatic nucleus transmits time of day information by a diurnal spiking rhythm that is driven by intrinsic activity of molecular clock genes controlling membrane excitability. Most brain region
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d5b713b503b8592d7a093534e8aeb0a
https://doi.org/10.1101/2022.06.28.497975
https://doi.org/10.1101/2022.06.28.497975
