Výsledky vyhledávání - "Jacques Hatzfeld"

Comparative proteomic analysis of human mesenchymal and embryonic stem cells: Towards the definition of a mesenchymal stem cell proteomic signature

Autor: Christian Jorgensen, Romain Barbet, Stéphane Roche, Bruno Delorme, Louis Casteilla, Danièle Noël, Pierre Charbord, Helen A. Papadaki, Jacques Hatzfeld, Karim Boumediene, Béatrice Cousin, Carole Crozet, Ollivier Milhavet, Robert A.J. Oostendorp, Sylvain Lehmann, David Caton

Publikováno v: Proteomics
Proteomics, Wiley-VCH Verlag, 2009, 9 (2), pp.223-232. ⟨10.1002/pmic.200800035⟩

International audience; Mesenchymal stem cells (MSC) are adult multipotential progenitors which have a high potential in regenerative medicine. They can be isolated from different tissues throughout the body and their homogeneity in terms of phenotyp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::508109ea55c911de017156f5bb9e5873
https://doi.org/10.1002/pmic.200800035

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Use of Xenofree Matrices and Molecularly-Defined Media to Control Human Embryonic Stem Cell Pluripotency: Effect of Low Physiological TGF-βConcentrations

Autor: Isabelle Peiffer, Jacques Hatzfeld, Yi-Ping Zhou, Ma-Lin Li, Marie-Noëlle Monier, Romain Barbet, Antoinette Hatzfeld

Publikováno v: Stem Cells and Development. 17:519-534

To monitor human embryonic stem cell (hESC) self-renewal without differentiation, we used quantitative RT-PCR to study a selection of hESC genes, including markers for self-renewal, commitment/differentiation, and members of the TGF-beta superfamily

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::424af8604a76b801af57c744cc126fe4
https://doi.org/10.1089/scd.2007.0279

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Simultaneous Differentiation of Endothelial and Trophoblastic Cells Derived from Human Embryonic Stem Cells

Autor: Ma-Lin Li, Romain Barbet, Isabelle Peiffer, Valerie Haydont, Denis Belhomme, Yi-Ping Zhou, Jean-Noël Fabiani, Antoinette Hatzfeld, Nicolas O. Fortunel, Jacques Hatzfeld

Publikováno v: Stem Cells and Development. 16:393-402

Here we present a simple two-step in vitro model of vascularized trophoblastic tissue derived from human embryonic stem (hES) cells. The first step is the formation of cystic embryoid bodies (EBs) in suspension in a semisolid methyl cellulose medium,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da87849531ebda03aeb0794c139c67d9
https://doi.org/10.1089/scd.2006.0013

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Les cellules souches embryonnaires humaines : problèmes pratiques et potentialités scientifiques

Autor: Jacques Hatzfeld, Isabelle Peiffer, Antoinette Hatzfeld

Publikováno v: Pathologie Biologie. 54:94-99

Human embryonic stem cells (hESCs) are derived from pre-implantation embryos given to research with the informed consent of the parents. These cells cannot give rise to a human being: they are not totipotent. They have an unlimited self-renewal capac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::585d40372068f5144d44ae1b14330803
https://doi.org/10.1016/j.patbio.2005.06.003

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p21cip1 mRNA is controlled by endogenous transforming growth factor-?1 in quiescent human hematopoietic stem/progenitor cells

Autor: Jacques Hatzfeld, Marie-Noëlle Monier, Karin Ducos, Antoinette Hatzfeld, Nicolas O. Fortunel, Béatrice Panterne

Publikováno v: Journal of Cellular Physiology. 184:80-85

Transforming growth factor-β1 (TGF-β1) has been described as an efficient growth inhibitor that maintains the CD34+ hematopoietic progenitor cells in quiescence. The concept of high proliferative potential-quiescent cells or HPP-Q cells has been in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bf5eecf8fd9984e39a9e4f79c091b6cc
https://doi.org/10.1002/(sici)1097-4652(200007)184:1<80::aid-jcp8>3.0.co

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Release from Quiescence of Primitive Human Hematopoietic Stem/Progenitor Cells by Blocking Their Cell‐Surface TGF‐β Type II Receptor in a Short‐Term In Vitro Assay

Autor: Karin Ducos, Angelo A. Cardoso, Pascal Batard, Marie-Noëlle Monier, Antoinette Hatzfeld, Sergueï Kisselev, Jacques Hatzfeld, Nicolas O. Fortunel

Publikováno v: STEM CELLS. 18:102-111

Genetic alterations of the signaling cascade of transforming growth factor-beta (TGF-beta) are often associated with neoplastic transformation of primitive cells. This demonstrates the key role for this pleiotropic factor in the control of quiescence

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35d455aa4d37917eaa97b9c2216edd69
https://doi.org/10.1634/stemcells.18-2-102

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TGF-(beta)1 maintains hematopoietic immaturity by a reversible negative control of cell cycle and induces CD34 antigen up-modulation

Autor: Jacques Hatzfeld, T. Phan, Antoinette Hatzfeld, Pascal Batard, Nicolas O. Fortunel, Marie-Noëlle Monier, P. Sansilvestri-Morel, Karin Ducos

Publikováno v: Journal of Cell Science. 113:383-390

Somatic stem cells are largely quiescent in spite of their considerable proliferative potential. Transforming growth factor-(beta)1 (TGF-(beta)1) appears to be a good candidate for controlling this quiescence. Indeed, various mutations in the TGF-bet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03de9362463f811b9c010f88655e22a5
https://doi.org/10.1242/jcs.113.3.383

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Increased Stable Retroviral Gene Transfer in Early Hematopoietic Progenitors Released from Quiescence

Autor: Pascal Batard, Jacques Hatzfeld, Frédéric Taieb, Antoinette Hatzfeld, Béatrice Panterne

Publikováno v: Human Gene Therapy
Human Gene Therapy, 1996, 7 (2), pp.207-213. ⟨10.1089/hum.1996.7.2-207⟩
Human Gene Therapy, Mary Ann Liebert, 1996, 7 (2), pp.207-213. ⟨10.1089/hum.1996.7.2-207⟩
Scopus-Elsevier

It has been previously demonstrated that prestimulation with cytokines could improve gene transfer in hematopoietic progenitors. However, we have shown that no combination of cytokines so far tested is able to release rapidly in vitro the stem cell c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dce40fb94a6d5e3ac5219381e502005
https://doi.org/10.1089/hum.1996.7.2-207

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Comparison of Gene Expression in Human Embryonic Stem Cells, hESC-Derived Mesenchymal Stem Cells and Human Mesenchymal Stem Cells

Autor: Isabelle Peiffer, Jacques Hatzfeld, Pierre Charbord, Romain Barbet, Antoinette Hatzfeld

Publikováno v: Stem Cells International, Vol 2011 (2011)
Stem Cells International

We present a strategy to identify developmental/differentiation and plasma membrane marker genes of the most primitive human Mesenchymal Stem Cells (hMSCs). Using sensitive and quantitative TaqMan Low Density Arrays (TLDA) methodology, we compared th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcc5da470ada77abce5c4363b7a90da0

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Fibrinogen potentiates the effect of interleukin-3 on early human hematopoietic progenitors

Autor: Jacques Hatzfeld, Jean-Pierre Levesque, Antoinette Hatzfeld, Yi-Qing Zhou, Angelo A. Cardoso, P Sansilvestri, Ma-Lin Li

Publikováno v: Blood. 82:800-806

The effect of human fibrinogen on the proliferation of purified SBA- CD34+ human bone marrow progenitors was investigated in clonal cultures. Fibrinogen alone or in combination with erythropoietin had no significant effect. However, in the presence o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::62ad2e1cce9516125e2eadb69bd49e16
https://doi.org/10.1182/blood.v82.3.800.800

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