Rapid Typing of Transmissible Spongiform Encephalopathy Strains with Differential ELISA

Autor: Stéphanie Simon, Jérôme Nugier, Nathalie Morel, Hervé Boutal, Christophe Créminon, Sylvie L. Benestad, Olivier Andréoletti, Frédéric Lantier, Jean-Marc Bilheude, Muriel Feyssaguet, Anne-Gaëlle Biacabe, Thierry Baron, Jacques Grassi

Publikováno v: Emerging Infectious Diseases, Vol 14, Iss 4, Pp 608-616 (2008)

The bovine spongiform encephalopathy (BSE) agent has been transmitted to humans, leading to variant Creutzfeldt-Jakob disease. Sheep and goats can be experimentally infected by BSE and have been potentially exposed to natural BSE; however, whether BS

Externí odkaz: https://doaj.org/article/49b03365c3be4da2a5de46d9d8d7a5c1

Impact of leucocyte depletion and prion reduction filters on TSE blood borne transmission.

Autor: Caroline Lacroux, Daisy Bougard, Claire Litaise, Hugh Simmons, Fabien Corbiere, Dominique Dernis, René Tardivel, Nathalie Morel, Stephanie Simon, Séverine Lugan, Pierrette Costes, Jean Louis Weisbecker, François Schelcher, Jacques Grassi, Joliette Coste, Olivier Andréoletti

Publikováno v: PLoS ONE, Vol 7, Iss 7, p e42019 (2012)

The identification in the UK of 4 v-CJD infected patients thought to be due to the use of transfused Red Blood Cell units prepared from blood of donors incubating v-CJD raised major concerns in transfusion medicine. The demonstration of leucocyte ass

Externí odkaz: https://doaj.org/article/91a99f92206748e18af2781e66be0343

Transmissibility of atypical scrapie in ovine transgenic mice: major effects of host prion protein expression and donor prion genotype.

Autor: Jean-Noël Arsac, Dominique Bétemps, Eric Morignat, Cécile Féraudet, Anna Bencsik, Denise Aubert, Jacques Grassi, Thierry Baron

Publikováno v: PLoS ONE, Vol 4, Iss 10, p e7300 (2009)

Atypical scrapie or Nor98 has been identified as a transmissible spongiform encephalopathy (TSE) that is clearly distinguishable from classical scrapie and BSE, notably regarding the biochemical features of the protease-resistant prion protein PrP(re

Externí odkaz: https://doaj.org/article/5a77a0bafd3d4eba9981fd8150c7fde8

Beyond PrP9res) type 1/type 2 dichotomy in Creutzfeldt-Jakob disease.

Autor: Emmanuelle Uro-Coste, Hervé Cassard, Stéphanie Simon, Séverine Lugan, Jean-Marc Bilheude, Armand Perret-Liaudet, James W Ironside, Stéphane Haik, Christelle Basset-Leobon, Caroline Lacroux, Katell Peoch', Nathalie Streichenberger, Jan Langeveld, Mark W Head, Jacques Grassi, Jean-Jacques Hauw, Francois Schelcher, Marie Bernadette Delisle, Olivier Andréoletti

Publikováno v: PLoS Pathogens, Vol 4, Iss 3, p e1000029 (2008)

Sporadic Creutzfeldt-Jakob disease (sCJD) cases are currently subclassified according to the methionine/valine polymorphism at codon 129 of the PRNP gene and the proteinase K (PK) digested abnormal prion protein (PrP(res)) identified on Western blott

Externí odkaz: https://doaj.org/article/b4b622169ff8416bb3e11fae5b8545c4

Excretion of BSE and scrapie prions in stools from murine models

Autor: Carlos Maluquer de Motes, Stéphanie Simon, Rosina Girones, Maria Eugenia Herva, Juan María Torres, Jacques Grassi, Martí Pumarola

Publikováno v: Repositorio de Resultados de Investigación del INIA
Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria INIA
INIA: Repositorio de Resultados de Investigación del INIA

Faeces from infected animals have been suggested as a potential source of contamination and transmission of prion diseases in the environment. This work describes the development of a procedure for the detection of PrPres in stools which is based on

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64b80a90d94f6ad219a8a819ada81b1d
https://doi.org/10.1016/j.vetmic.2008.02.014