Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Jacques E. Gielen"'
The Friend leukemia virus (FLV)-infected cell line, T-3-Cl-2, undergoes a form of erythroid differentiation in culture when treated with an appropriate inducer, such as dimethylsulfoxide ((CH3)2SO). Thus, whereas untreated cells contain no detectable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2b46476acef3bebe69d67efd9baf3a9
https://doi.org/10.1159/000397535
https://doi.org/10.1159/000397535
Autor:
Marie-Paule Merville, Thérèse Jarry-Guichard, Frédéric Princen, Jacques E. Gielen, Daniel Gros, Vincent Bours, Pierre A. Robe
Publikováno v:
Carcinogenesis. 22:507-513
Connexins, the structural components of gap junctions, control cell growth and differentiation and are believed to belong to a family of tumour suppressor genes. Studies on connexin localization in brain showed that several of these proteins were exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0fdfe5c8c171e94c143eac353110e4c
https://doi.org/10.1093/carcin/22.3.507
https://doi.org/10.1093/carcin/22.3.507
Autor:
Marie-Paule Merville, Valérie Benoit, Vincent Bours, Anne-Cécile Hellin, Jacques E. Gielen, Sandra Huygen
Publikováno v:
Oncogene. 19:4787-4794
The tumor suppressor p53 plays a pivotal role in the cellular response to DNA damage as it controls DNA repair, cell cycle arrest and apoptosis. We studied the autoregulation of human p53 gene transcription in colon cancer cell lines. Wild-type p53 h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d5775b64a2363497a10186ab5bfad71
https://doi.org/10.1038/sj.onc.1203831
https://doi.org/10.1038/sj.onc.1203831
Autor:
Gustave Moonen, Brigitte Malgrange, Marie-Paule Merville, Vincent Bours, Pierre A. Robe, Jacques E. Gielen, Achille Stevenaert, Frédéric Princen, Didier Martin
Publikováno v:
Biochemical Pharmacology. 60:241-249
The herpes simplex virus type 1 thymidine kinase (HSV1-tk) suicide gene/ganciclovir system was first applied to the treatment of glioblastoma tumors, but was hampered by the low gene transfection yield. Fortunately, the gap junction-dependent diffusi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c470bbacf8c15adfaa92a17a7734b5f
https://doi.org/10.1016/s0006-2952(00)00315-4
https://doi.org/10.1016/s0006-2952(00)00315-4
Publikováno v:
Biochemical Pharmacology. 34:1821-1826
The 7,8-epoxidation of benzo[ a ]pyrene, and the 9,10-epoxidation of benzo[ a ]-pyrene trans -7,8,-dihydrodiol coupled with covalent binding of the highly reactive diol-epoxide, are two key P-450-mediated reactions believed to be important in cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ac1dec532899741055810425a7798c6
https://doi.org/10.1016/0006-2952(85)90655-0
https://doi.org/10.1016/0006-2952(85)90655-0
Publikováno v:
Nature New Biology. 236:107-110
MANY mixed function1 oxygenases are membrane-bound multicomponent enzyme systems which require NADPH and molecular oxygen for the oxidative metabolism of polycyclic hydrocarbons, drugs and insecticides, as well as numerous lipophilic endogenous subst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d63f36c95fd438fb8f82bb709779ab94
https://doi.org/10.1038/newbio236107a0
https://doi.org/10.1038/newbio236107a0
Publikováno v:
Journal of Biological Chemistry. 247:1125-1137
In the inbred C57BL/6N mouse, aryl hydrocarbon hydroxylase induction by polycyclic hydrocarbons increases rapidly in the neonatal period; this response to these pharmacological, exogenous compounds does not appear in the DBA/2N, NZW/BLN, or NZB/BLN s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4d98e4626196e754041ef6251a8ead5
https://doi.org/10.1016/s0021-9258(19)45624-x
https://doi.org/10.1016/s0021-9258(19)45624-x
Publikováno v:
Cold Spring Harbor symposia on quantitative biology. 38
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c327b2ca442e185f39b1edf3e2f4cc56
https://pubmed.ncbi.nlm.nih.gov/4133990
https://pubmed.ncbi.nlm.nih.gov/4133990
Publikováno v:
Control of Gene Expression ISBN: 9781468432480
During the development of an embryo, various processes occur which induce the formation of differentiated tissues. Some of these processes can be observed at a molecular level, for example, myosin is synthesized in muscle cells, crystaline in lens ti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b65f20c55d9839c787cbe58bb1d9ceba
https://doi.org/10.1007/978-1-4684-3246-6_11
https://doi.org/10.1007/978-1-4684-3246-6_11
Publikováno v:
Journal of molecular biology. 87(4)
A cultured, murine erythroleukemic cell line, which initially contains no detectable hemoglobin, can be induced to synthesize hemoglobin in quantities comparable to those found in normal red blood cells. In order to distinguish between several molecu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c8f13d6786bef79e57b4ee308533f07
https://pubmed.ncbi.nlm.nih.gov/4530120
https://pubmed.ncbi.nlm.nih.gov/4530120